Antanasijevic Lab – Virology and Structural Immunology
Anti-HIV antibody uses its HCDR3 loop (light green) to engage the HIV Env antigen (light gray). CryoEM density map is shown as a transparent gray surface.
The evolution of technology in recent years has accelerated the development of vaccine and therapeutic solutions against various diseases and enabled us to study them with unprecedented detail. Our lab uses state-of-the-art structural and computational biology tools to obtain molecular-level understanding of how different viral pathogens are assembled and how they interact with the host immune system. As our primary goal, we seek to define the rules for efficient engagement of antibody-mediated response and apply that information to develop novel vaccines and antibody therapeutics.
