Publications

Google Scholar profile of Anne-Florence Bitbol

2024

Evolution of cooperation in deme-structured populations on graphs

A. Moawad; A. Abbara; A-F. Bitbol 

Physical Review E. 2024. Vol. 109, num. 2, p. 024307. DOI : 10.1103/PhysRevE.109.024307.

Universal Casimir attraction between filaments at the cell scale

B. Spreng; H. Berthoumieux; A. Lambrecht; A-F. Bitbol; P. Maia Neto et al. 

New Journal Of Physics. 2024. Vol. 26, num. 1, p. 013009. DOI : 10.1088/1367-2630/ad1846.

Impact of phylogeny on inference from protein sequences: from models to natural data

N. Dietler / A-F. Bitbol (Dir.)  

Lausanne, EPFL, 2024. 

Impact of spatial structure and finite size on the evolution and ecology of asexual microbial populations

R. M. Servajean / A-F. Bitbol (Dir.)  

Lausanne, EPFL, 2024. 

Interactions between pili affect the outcome of bacterial competition driven by the type VI secretion system

S. B. Otto; R. M. Servajean; A. Lemopoulos; A-F. Bitbol; M. Blokesch 

Current Biology. 2024. Vol. 34, p. https://doi.org/10.1016/j.cub.2024.04.041. DOI : 10.1016/j.cub.2024.04.041.

2023

Frequent asymmetric migrations suppress natural selection in spatially structured populations

A. Abbara; A-F. Bitbol 

Pnas Nexus. 2023. Vol. 2, num. 11, p. pgad392. DOI : 10.1093/pnasnexus/pgad392.

Impact of population size on early adaptation in rugged fitness landscapes

R. Servajean; A-F. Bitbol 

Philosophical Transactions Of The Royal Society B-Biological Sciences. 2023. Vol. 378, num. 1877, p. 20220045. DOI : 10.1098/rstb.2022.0045.

Combining phylogeny and coevolution improves the inference of interaction partners among paralogous proteins

C. Gandarilla-Perez; S. Pinilla; A-F. Bitbol; M. Weigt 

Plos Computational Biology. 2023. Vol. 19, num. 3, p. e1011010. DOI : 10.1371/journal.pcbi.1011010.

Impact of phylogeny on structural contact inference from protein sequence data

N. Dietler; U. Lupo; A-F. Bitbol 

Journal Of The Royal Society Interface. 2023. Vol. 20, num. 199, p. 20220707. DOI : 10.1098/rsif.2022.0707.

Generative power of a protein language model trained on multiple sequence alignments

D. Sgarbossa; U. Lupo; A-F. Bitbol 

Elife. 2023. Vol. 12, p. e79854. DOI : 10.7554/eLife.79854.

Interactions between pili affect the outcome of bacterial competition driven by the type VI secretion system

S. B. Otto; R. M. Servajean; A. Lemopoulos; A-F. Bitbol; M. Blokesch 

2023

2022

Protein language models trained on multiple sequence alignments learn phylogenetic relationships

U. Lupo; D. Sgarbossa; A-F. Bitbol 

Nature Communications. 2022. Vol. 13, num. 1, p. 6298. DOI : 10.1038/s41467-022-34032-y.

Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences

A. Gerardos; N. Dietler; A-F. Bitbol 

Plos Computational Biology. 2022. Vol. 18, num. 5, p. e1010147. DOI : 10.1371/journal.pcbi.1010147.

Extracting phylogenetic dimensions of coevolution reveals hidden functional signals

A. Colavin; E. Atolia; A-F. Bitbol; K. C. Huang 

Scientific Reports. 2022. Vol. 12, num. 1, p. 820. DOI : 10.1038/s41598-021-04260-1.

Hydrodynamic flow and concentration gradients in the gut enhance neutral bacterial diversity

D. Labavić; C. Loverdo; A-F. Bitbol 

Proceedings of the National Academy of Sciences. 2022. Vol. 119, num. 1, p. e2108671119. DOI : 10.1073/pnas.2108671119.

2021

Toward a Universal Model for Spatially Structured Populations

L. Marrec; I. Lamberti; A-F. Bitbol 

Physical Review Letters. 2021. Vol. 127, num. 21, p. 218102. DOI : 10.1103/PhysRevLett.127.218102.

Evolutionary history expands the range of signaling interactions in hybrid multikinase networks

P. Ortet; S. Fochesato; A-F. Bitbol; D. E. Whitworth; D. Lalaouna et al. 

Scientific Reports. 2021. Vol. 11, num. 1, p. 11763. DOI : 10.1038/s41598-021-91260-w.

2020

A convolutional neural network segments yeast microscopy images with high accuracy

N. Dietler; M. Minder; V. Gligorovski; A. M. Economou; D. A. H. L. Joly et al. 

Nature Communications. 2020. Vol. 11, num. 1, p. 5723. DOI : 10.1038/s41467-020-19557-4.

Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

L. Marrec; A-F. Bitbol 

Genetics. 2020. Vol. 216, num. 2, p. 573 – 583. DOI : 10.1534/genetics.120.303624.

Resist or perish: Fate of a microbial population subjected to a periodic presence of antimicrobial

L. Marrec; A-F. Bitbol 

PLOS Computational Biology. 2020. Vol. 16, num. 4, p. e1007798. DOI : 10.1371/journal.pcbi.1007798.

Statistical physics of interacting proteins: Impact of dataset size and quality assessed in synthetic sequences

C. A. Gandarilla-Pérez; P. Mergny; M. Weigt; A-F. Bitbol 

Physical Review E. 2020. Vol. 101, num. 3, p. 032413. DOI : 10.1103/PhysRevE.101.032413.

Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance

P. Thomen; J. D. P. Valentin; A-F. Bitbol; N. Henry 

Soft Matter. 2020. Vol. 16, num. 2, p. 494 – 504. DOI : 10.1039/C9SM01375J.

2019

Phylogenetic correlations can suffice to infer protein partners from sequences

G. Marmier; M. Weigt; A-F. Bitbol 

PLOS Computational Biology. 2019. Vol. 15, num. 10, p. e1007179. DOI : 10.1371/journal.pcbi.1007179.

Antibody‐mediated crosslinking of gut bacteria hinders the spread of antibiotic resistance

F. Bansept; L. Marrec; A-F. Bitbol; C. Loverdo 

Evolution. 2019. Vol. 73, num. 6, p. 1077 – 1088. DOI : 10.1111/evo.13730.

Revealing evolutionary constraints on proteins through sequence analysis

S-W. Wang; A-F. Bitbol; N. S. Wingreen 

PLOS Computational Biology. 2019. Vol. 15, num. 4, p. e1007010. DOI : 10.1371/journal.pcbi.1007010.

2018

Inferring interaction partners from protein sequences using mutual information

A-F. Bitbol 

PLOS Computational Biology. 2018. Vol. 14, num. 11, p. e1006401. DOI : 10.1371/journal.pcbi.1006401.

Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in a homogeneous microbial population of fixed size

L. Marrec; A-F. Bitbol 

Journal of Theoretical Biology. 2018. Vol. 457, p. 190 – 198. DOI : 10.1016/j.jtbi.2018.08.040.

pH sensing by lipids in membranes: The fundamentals of pH-driven migration, polarization and deformations of lipid bilayer assemblies

M. I. Angelova; A-F. Bitbol; M. Seigneuret; G. Staneva; A. Kodama et al. 

Biochimica et Biophysica Acta (BBA) – Biomembranes. 2018. Vol. 1860, num. 10, p. 2042 – 2063. DOI : 10.1016/j.bbamem.2018.02.026.

Membrane-Mediated Interactions

P. Bassereau; P. Sens; A-F. Bitbol; D. Constantin; J-B. Fournier 

Physics of Biological Membranes; Springer International Publishing, 2018. p. 311 – 350.

2017

Bacterial biofilm under flow: First a physical struggle to stay, then a matter of breathing

P. Thomen; J. Robert; A. Monmeyran; A-F. Bitbol; C. Douarche et al. 

PLOS ONE. 2017. Vol. 12, num. 4, p. e0175197. DOI : 10.1371/journal.pone.0175197.

2016

Inferring interaction partners from protein sequences

A-F. Bitbol; R. S. Dwyer; L. J. Colwell; N. S. Wingreen 

Proceedings of the National Academy of Sciences. 2016. Vol. 113, num. 43, p. 12180 – 12185. DOI : 10.1073/pnas.1606762113.

Characterizing the Statistical Properties of Protein Surfaces

J. H. Bak; A-F. Bitbol; W. Bialek 

2016. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, February 27-March 02, 2016. p. 535a – 536a. DOI : 10.1016/j.bpj.2015.11.2868.

2015

Fundamental Constraints on the Abundances of Chemotaxis Proteins

A-F. Bitbol; N. Wingreen 

Biophysical Journal. 2015. Vol. 108, num. 5, p. 1293 – 1305. DOI : 10.1016/j.bpj.2015.01.024.

Fundamental Constraints on the Abundances of Chemotaxis Proteins

A-F. Bitbol; N. S. Wingreen 

2015. 59th Annual Meeting of the Biophysical-Society, Baltimore, MD, February 07-11, 2015. DOI : 10.1016/j.bpj.2014.11.2000.

Direct Monolayer Packing Imbalance and Phospholipid Flip-Flop: Two Mechanisms of Local Bilayer Deformation. Application to Mitochondrial Cristae of Wild-Type and Cardiolipin-Deficient Mutant

N. Khalifat; M. Rahimi; A-F. Bitbol; M. Seigneuret; J-B. Fournier et al. 

2015. 59th Annual Meeting of the Biophysical-Society, Baltimore, MD, February 07-11, 2015. DOI : 10.1016/j.bpj.2014.11.024.

2014

Quantifying the Role of Population Subdivision in Evolution on Rugged Fitness Landscapes

A-F. Bitbol; D. J. Schwab 

PLoS Computational Biology. 2014. Vol. 10, num. 8, p. e1003778. DOI : 10.1371/journal.pcbi.1003778.

Interplay of Packing and Flip-flop in Local Bilayer Deformation. How Phosphatidylglycerol Could Rescue Mitochondrial Function in a Cardiolipin-deficient Yeast Mutant

N. Khalifat; M. Rahimi; A-F. Bitbol; M. Seigneuret; J-B. Fournier et al. 

Biophysical Journal. 2014. Vol. 107, num. 4, p. 879 – 890. DOI : 10.1016/j.bpj.2014.07.015.

Large-scale filament formation inhibits the activity of CTP synthetase

R. M. Barry; A-F. Bitbol; A. Lorestani; E. J. Charles; C. H. Habrian et al. 

eLife. 2014. Vol. 3, p. e03638. DOI : 10.7554/eLife.03638.

2013

Pairwise summation approximation for Casimir potentials and its limitations

A-F. Bitbol; A. Canaguier-Durand; A. Lambrecht; S. Reynaud 

Physical Review B. 2013. Vol. 87, num. 4, p. 045413. DOI : 10.1103/PhysRevB.87.045413.

Elasticity of Lipid Bilayer Membranes at the Nanoscale: The Need for New Terms

A-F. Bitbol; D. Constantin; J-B. Fournier 

2013. 57th Annual Meeting of the Biophysical-Society, Philadelphia, PA, February 02-06, 2013. DOI : 10.1016/j.bpj.2012.11.1374.

Membrane properties revealed by spatiotemporal response to a local inhomogeneity

A-F. Bitbol; J-B. Fournier 

Biochimica et Biophysica Acta (BBA) – Biomembranes. 2013. Vol. 1828, num. 4, p. 1241 – 1249. DOI : 10.1016/j.bbamem.2012.11.024.

2012

Bilayer Elasticity at the Nanoscale: The Need for New Terms

A-F. Bitbol; D. Constantin; J-B. Fournier 

PLoS ONE. 2012. Vol. 7, num. 11, p. e48306. DOI : 10.1371/journal.pone.0048306.

Lipid Membrane Deformation in Response to a Local pH Modification

A-F. Bitbol; N. Puff; Y. Sakuma; M. Imai; J-B. Fournier et al. 

2012. 56th Annual Meeting of the Biophysical-Society, San Diego, CA, February 25-29, 2012. DOI : 10.1016/j.bpj.2011.11.209.

Lipid membrane deformation in response to a local pH modification: theory and experiments

A-F. Bitbol; N. Puff; Y. Sakuma; M. Imai; J-B. Fournier et al. 

Soft Matter. 2012. Vol. 8, num. 22, p. 6073. DOI : 10.1039/c2sm25519g.

Fluctuations of the Casimir-like force between two inclusions in a biological membrane

A-F. Bitbol; J-B. Fournier 

2012. 176th Course of the International School of Physics Enrico Fermi on Complex Materials in Physics and Biology, Varenna, ITALY, JUN 29-JUL 09, 2010. p. 387 – 391. DOI : 10.3254/978-1-61499-071-0-387.

2011

Universal amplitudes of the Casimir-like interactions between four types of rods in fluid membranes

A-F. Bitbol; K. Sin Ronia; J-B. Fournier 

EPL (Europhysics Letters). 2011. Vol. 96, num. 4, p. 40013. DOI : 10.1209/0295-5075/96/40013.

Dynamical membrane curvature instability controlled by intermonolayer friction

A-F. Bitbol; J-B. Fournier; M. I. Angelova; N. Puff 

Journal of Physics: Condensed Matter. 2011. Vol. 23, num. 28, p. 284102. DOI : 10.1088/0953-8984/23/28/284102.

Forces exerted by a correlated fluid on embedded inclusions

A-F. Bitbol; J-B. Fournier 

Physical Review E. 2011. Vol. 83, num. 6, p. 061107. DOI : 10.1103/PhysRevE.83.061107.

Membrane stress tensor in the presence of lipid density and composition inhomogeneities

A-F. Bitbol; L. Peliti; J. -B. Fournier 

The European Physical Journal E. 2011. Vol. 34, num. 5, p. 53. DOI : 10.1140/epje/i2011-11053-4.

2010

Fluctuations of the Casimir-like force between two membrane inclusions

A-F. Bitbol; P. G. Dommersnes; J-B. Fournier 

Physical Review E. 2010. Vol. 81, num. 5, p. 050903. DOI : 10.1103/PhysRevE.81.050903.

2009

Scaling and dynamics of washboard roads

A-F. Bitbol; N. Taberlet; S. W. Morris; J. N. McElwaine 

Physical Review E. 2009. Vol. 79, num. 6, p. 061308. DOI : 10.1103/PhysRevE.79.061308.