Just as epigenetic mechanisms contribute to cognitive decline, they also contribute to engrave memories from the past. In the case of traumatic memories this is a problem, and anxiety disorders such as PTSD can be the consequence. Using an animal model of PTSD in combination with cognitive behavioral therapy-like approaches, engram techniques, pharmacological interventions and epigenetic investigations, we are aiming at elucidating the molecular basis for resilient traumatic memories and their attenuation. Please refer to the publications below for further reading.
