Boosting CAR T-cell therapy through G-protein signal rewiring

Lat-based nk cars and their use

M. Girardin; A. Madurga Alonso; J. Huelsken 

Metabolic dependencies of metastasis-initiating cells in female breast cancer

C. M. Young; L. N. K. Beziaud; P. V. Dessen; A. M. Alonso; A. Santamaria-Martinez et al. 

IFNγ-induced stem-like state of cancer cells as a driver of metastatic progression following immunotherapy

L. Beziaud; C. M. Young; A. R. Minafra; M. Norkin; A. Madurga Alonso et al. 

Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma

G. M. Ramzy; M. Norkin; T. Koessler; L. Voirol; M. Tihy et al. 

Metabolic dependencies of metastasis-initiating cells in breast cancer

Countering T cell exhaustion and senescence for enhanced adoptive T cell therapies against solid tumors

Unlocking Hidden Potential: Exploring the Complexities of Signaling in Immune Cell Activation to Optimize CAR Therapy

Development of a novel Chimeric Antigen Receptor (CAR) for its use in Natural Killer (NK) cells for cancer treatment and beyond

Mechanism of KRAS-driven T cell infiltration in colorectal cancer

Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function

I. M. Roy; P. V. Anu; S. Zaunz; S. Reddi; A. M. Giri et al. 

Role Of Outside-In Integrin Signaling In Hematopoietic Development Of Mouse Embryo

A. Biswas; I. Roy; J. Huelsken; A. Lacy-Hulbert; C. Verfaillie et al. 

The role of eosinophils in breast cancer

High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

M. Norkin; P. Ordóñez-Morán; J. Huelsken 

Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes

V. S. Dionellis; M. Norkin; A. Karamichali; G. G. Rossetti; J. Huelsken et al. 

Niche-Mediated Integrin Signaling Supports Steady-State Hematopoiesis in the Spleen

S. H. Mehatre; I. M. Roy; A. Biswas; D. Prit; S. Schouteden et al. 

Intestinal stem cells differentiation and its application in cancer therapy

TGFBI modulates tumour hypoxia and promotes breast cancer metastasis

F. Fico; A. Santamaria-Martinez 

The Periostin/Integrin-alpha v Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver

A. Biswas; I. M. Roy; P. C. Babu; J. Manesia; S. Schouteden et al. 

Quantitative approaches to unravel bone marrow adipocyte site-specificity and its implication in hematopoiesis