ApatTIs

Treating apathy by non-invasive transcranial temporal interference stimulation (tTIS) of the striatum

Apathy is a transdiagnostic syndrome of impaired motivation which has a large impact on quality of life and is extremely prevalent in a variety of neuropsychiatric disorders including traumatic brain injury (61%), Alzheimer’s disease (49%), Parkinson’s disease (40%) and stroke (36%).

The apatTIS project aims at obtaining a comprehensive understanding of striatal neuromodulation effects on motivated behavior in healthy participants and patients suffering from apathy, testing the effectiveness of this approach toward clinical translation.

Researchers

Pierre Vassilliadis

Simona Losacco

Michele Di Ponzio