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Our two main research axes are high speed atomic force microscopy and the combination of different microscopy techniques.
![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/12/FeaturedImage_Microfab.jpg)
We focus mainly on the fabrication of various AFM cantilevers. Our approach is to optimise the performance through material engineering.
News
Publications
A biphasic growth model for cell pole elongation in mycobacteria
Nature Communications. 2020-01-23. Vol. 11, p. 452. DOI : 10.1038/s41467-019-14088-z.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2020/02/2216x1244-1024x575.jpg)
Integration of sharp silicon nitride tips into high-speed SU8 cantilevers in a batch fabrication process
Beilstein Journal of Nanotechnology. 2019-11-29. Vol. 10, p. 2357–2363. DOI : 10.3762/bjnano.10.226.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/12/2190-4286-10-226-1.png)
Overlapping and essential roles for molecular and mechanical mechanisms in mycobacterial cell division
Nature Physics. 2020. Vol. 16, p. 57–62. DOI : 10.1038/s41567-019-0679-1.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/41567_2019_679_MOESM3_ESM-1.gif)
Batch Fabrication of Multilayer Polymer Cantilevers with Integrated Hard Tips for High-Speed Atomic Force Microscopy
2019-08-22. Transducers & Eurosensors XXXIII, Berlin, Germany, June 23-27, 2019. DOI : 10.1109/TRANSDUCERS.2019.8808606.Large‐Range HS‐AFM Imaging of DNA Self‐Assembly through In Situ Data‐Driven Control
Small Methods. 2019. Vol. 3, p. 1900031. DOI : 10.1002/smtd.201900031.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/smtd201900031-sup-0001-s1.gif)
Single-molecule kinetics of pore assembly by the membrane attack complex
Nature Communications. 2019-05-06. Vol. 10, p. 2066. DOI : 10.1038/s41467-019-10058-7.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/41467_2019_10058_Fig1_HTML-1024x523.jpg)
Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG
Molecular Microbiology. 2019-05-01. Vol. 111, num. 5, p. 1263-1282. DOI : 10.1111/mmi.14220.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/mmi14220-fig-0006-m-1024x689.jpg)
Detecting topological variations of DNA at single-molecule level
Nature Communications. 2019. Vol. 10, p. 3. DOI : 10.1038/s41467-018-07924-1.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/41467_2018_7924_Fig1_HTML-1024x546.png)
An analog high-speed single-cycle lock-in amplifier for next generation AFM experiments
2018-01-01. 17th IEEE SENSORS Conference, New Delhi, INDIA, Oct 28-31, 2018. p. 168-171. DOI : 10.1109/ICSENS.2018.8589857.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/1747-fig-5-source-large.gif)
Air and Water-Stable n-Type Doping and Encapsulation of Flexible MoS2 Devices with SU8
Advanced Electronic Materials. 2018-11-09. p. 1800492. DOI : 10.1002/aelm.201800492.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/aelm201800492-fig-0001-m-1024x317.jpg)
Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape
Elife. 2018-10-16. Vol. 7, p. e37516. DOI : 10.7554/eLife.37516.Photothermal Off-Resonance Tapping for Rapid and Gentle Atomic Force Imaging of Live Cells
International Journal of Molecular Sciences. 2018-09-30. Vol. 19, num. 10, p. 2984. DOI : 10.3390/ijms19102984.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/supplementary_video_2.gif)
Reducing uncertainties in energy dissipation measurements in atomic force spectroscopy of molecular networks and cell-adhesion studies
Scientific Reports. 2018-06-20. Vol. 8, num. 1, p. 9390. DOI : 10.1038/s41598-018-26979-0.High-speed photothermal off-resonance atomic force microscopy reveals assembly routes of centriolar scaffold protein SAS-6
Nature Nanotechnology. 2018-08-13. Vol. 13, num. 8, p. 696-701. DOI : 10.1038/s41565-018-0149-4.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/10/sas6.gif)
Digitally controlled analog proportional-integral-derivative (PID) controller for high-speed scanning probe microscopy
Review of Scientific Instruments. 2017. Vol. 88, num. 12, p. 123712. DOI : 10.1063/1.5010181.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/11/1.5010181.figures.online.f5-1024x671.png)
Components for high-speed atomic force microscopy optimized for low phase-lag
2017. 2017 IEEE International Conference on Advanced Intelligent Mechatronics (AIM), Munich, Germany, 3-7 July 2017. p. 731-736. DOI : 10.1109/AIM.2017.8014104.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/11/8014104-fig-1-source-large.gif)
Microfluidic bacterial traps for simultaneous fluorescence and atomic force microscopy
Nano Research. 2017. Vol. 10, num. 11, p. 3896-3908. DOI : 10.1007/s12274-017-1604-5.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2019/11/image.png)
Probing the Morphology and Evolving Dynamics of 3D Printed Nanostructures Using High-Speed Atomic Force Microscopy
Acs Applied Materials & Interfaces. 2017. Vol. 9, num. 29, p. 24456-24461. DOI : 10.1021/acsami.7b07762.![](https://www.epfl.ch/labs/lbni/wp-content/uploads/2018/08/20_img.jpg)