LCBM
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Positions:
There are open positions for PhD students and Postdocs!
We have been awarded a SNSF Advanced Grant, which will start in 2024! We are thus assembling a high-powered team of PhD students and postdocs for the challenging and exciting project “Site-specific Access of Regulatory Chromatin in Cells – siteSEARCH“. If you are interested to join, contact directly: beat.fierz@epfl.ch.
PRODIGY
The LCBM is a member of the PRODIGY consortium – Protein-based molecular design for next generation Therapy. Check out details here:
New paper!
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New paper!
Structural basis of Sirt7 regulation
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New preprint!
Single-molecule chromatin ubiquitylation by PRC1
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New collaborative paper!
What happens during chromatin aging? A great collaboration with the Müller lab at King’s College London.
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H1 ubiquitylation controls RNF168.
Chemically di-ubiquitylated H1 variants reveal position-dependent stimulation of the DNA repair protein RNF168
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Dynamics of centrochromatin.
CENP-A and CENP-B collaborate to create an open centromeric chromatin state
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Tubulin engineering.
Tubulin engineering by semisynthesis reveals that polyglutamylation directs detyrosination