Publications

2024

Swelling and Degrafting of Poly(3-sulfopropyl methacrylate) Brushes

S. Sant; K. Kaur; H-A. Klok 

Langmuir. 2024. Vol. 40, num. 41, p. 21656 – 21662. DOI : https://doi.org/10.1021/acs.langmuir.4c02714.

Synthesis of Amino Acid-Based Aromatic Poly(Ester Urea)s Using 4-Hydroxycinnamic Acid-Derived Diols

G. Tekleab; H-A. Klok 

Macromolecular Rapid Communications. 2024. DOI : https://doi.org/10.1002/marc.202400507.

The Structural Dispersity of Oligoethylene Glycol-Containing Polymer Brushes Determines Their Interfacial Properties

C. Pavon; A. Ongaro; I. Filipucci; S. N. Ramakrishna; A. Mattarei et al. 

Journal Of The American Chemical Society. 2024. DOI : 10.1021/jacs.4c05565.

Disulfide-Cross-Linked Tetra-PEG Gels

Z. Meng; L. Loeser; K. Saalwaechter; U. Gasser; H-A. Klok 

Macromolecules. 2024. Vol. 57, num. 7, p. 3058 – 3065. DOI : 10.1021/acs.macromol.3c02514.

Linear, Y- and Ψ-shaped poly(2-(dimethylamino)ethyl methacrylate) and poly(methyl methacrylate) brushes prepared by surface-initiated polymerization from a homologous series of ATRP initiators

S. Sant; H-A. Klok 

European Polymer Journal. 2024. Vol. 205, p. 112706. DOI : 10.1016/j.eurpolymj.2023.112706.

Pyroelectric Polyelectrolyte Brushes

J. Wang; F. Hu; S. Sant; K. Chu; L. Riemer et al. 

Advanced Materials. 2024. DOI : 10.1002/adma.202307038.

New Polymers from Biomass-Derived Hydroxycinnamic Acid Derivatives

G. Tekleab / H-A. Klok (Dir.)  

Lausanne, EPFL, 2024. 

Soft Mechanochemistry of Disulfide-Crosslinked Polymer Networks

Z. Meng / H-A. Klok (Dir.)  

Lausanne, EPFL, 2024. 

2023

Ductile, High-Lignin-Content Thermoset Films and Coatings

A. Boarino; J. Charmillot; M. B. Figueiredo; T. T. H. Le; N. Carrara et al. 

Acs Sustainable Chemistry & Engineering. 2023. Vol. 11, num. 46, p. 16442 – 16452. DOI : 10.1021/acssuschemeng.3c03030.

Supramolecular Polymer Brushes Grown by Surface-Initiated Atom Transfer Radical Polymerization from Cucurbit[7]uril-based Non-Covalent Initiators

F. K. Metze; I. Filipucci; H-A. Klok 

Angewandte Chemie-International Edition. 2023. Vol. 62, num. 34, p. e202305930. DOI : 10.1002/anie.202305930.

Fluorinated Poly(aryl piperidinium) Membranes for Anion Exchange Membrane Fuel Cells

X. Wu; N. Chen; C. Hu; H-A. Klok; Y. M. Lee et al. 

Advanced Materials. 2023. Vol. 35, num. 26, p. 2210432. DOI : 10.1002/adma.202210432.

Swelling-Activated, Soft Mechanochemistry in Polymer Materials

F. K. Metze; S. Sant; Z. Meng; H-A. Klok; K. Kaur 

Langmuir. 2023. DOI : 10.1021/acs.langmuir.2c02801.

Supramolecular Polymer Brushes

F. K. Metze; H. -A. Klok 

Acs Polymers Au. 2023. DOI : 10.1021/acspolymersau.2c00067.

Opportunities and Challenges for Lignin Valorization in Food Packaging, Antimicrobial, and Agricultural Applications

A. Boarino; H-A. Klok 

Biomacromolecules. 2023. DOI : 10.1021/acs.biomac.2c01385.

Supramolecular Polymer Brushes

F. K. Metze / H-A. Klok (Dir.)  

Lausanne, EPFL, 2023. 

Chemical Approaches for the Preparation of Bacteria – Nano/Microparticle Hybrid Systems

L. P. E. Bader; H-A. Klok 

Macromolecular Bioscience. 2023. Vol. 23, num. 8, p. 2200440. DOI : 10.1002/mabi.202200440.

Architecturally Diverse Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization

S. Sant / H-A. Klok (Dir.)  

Lausanne, EPFL, 2023. 

Lignin, from biomass waste to sustainable materials for food packaging, antiviral coatings and agriculture

A. Boarino / H-A. Klok (Dir.)  

Lausanne, EPFL, 2023. 

2022

Mechanical Acceleration of Ester Bond Hydrolysis in Polymers

J. Wang; X. Gao; A. Boarino; F. Celerse; C. Corminboeuf et al. 

Macromolecules. 2022. Vol. 55, num. 22, p. 10145 – 10152. DOI : 10.1021/acs.macromol.2c01789.

Lignin: A Sustainable Antiviral Coating Material

A. Boarino; H. Wang; F. Olgiati; F. Artusio; M. Ozkan et al. 

Acs Sustainable Chemistry & Engineering. 2022. DOI : 10.1021/acssuschemeng.2c04284.

Sustainable polyesters via direct functionalization of lignocellulosic sugars

L. P. Manker; G. R. Dick; A. Demongeot; M. A. Hedou; C. Rayroud et al. 

Nature Chemistry. 2022. Vol. 14, p. 976 – 984. DOI : 10.1038/s41557-022-00974-5.

Specific Counterion Effects on the Swelling Behavior of Strong Polyelectrolyte Brushes

K. Ehtiati; S. Z. Moghaddam; H-A. Klok; A. E. Daugaard; E. Thormann 

Macromolecules. 2022. Vol. 55, num. 12, p. 5123 – 5130. DOI : 10.1021/acs.macromol.2c00411.

Uniformly Dispersed Poly(lactic acid)-Grafted Lignin Nanoparticles Enhance Antioxidant Activity and UV-Barrier Properties of Poly(lactic acid) Packaging Films

A. Boarino; A. Schreier; Y. Leterrier; H-A. Klok 

Acs Applied Polymer Materials. 2022. DOI : 10.1021/acsapm.2c00420.

Macromolecular engineering via polyhomologation

F. Li; H-A. Klok 

European Polymer Journal. 2022. Vol. 171, p. 111195. DOI : 10.1016/j.eurpolymj.2022.111195.

Biodegradation of water-soluble and water-dispersible polymers for agricultural, consumer, and industrial applications-Challenges and opportunities for sustainable materials solutions

G. W. M. Vandermeulen; A. Boarino; H-A. Klok 

Journal Of Polymer Science. 2022. Vol. 60, num. 12, p. 1797 – 1813. DOI : 10.1002/pol.20210922.

Preparation and Analysis of Bacteria Surface-Modified with Polymer Nanoparticles

L. P. E. Bader / H-A. Klok (Dir.)  

Lausanne, EPFL, 2022. 

Branched Poly(Aryl Piperidinium) Membranes for Anion-Exchange Membrane Fuel Cells

X. Wu; N. Chen; H-A. Klok; Y. M. Lee; X. Hu 

Angewandte Chemie-International Edition. 2022.  p. e202114892. DOI : 10.1002/anie.202114892.

2021

Reduction-Sensitive Protein Nanogels Enhance Uptake of Model and Tumor Lysate Antigens In Vitro by Mouse- and Human-Derived Dendritic Cells

C. Berti; A. Boarino; M. Graciotti; L. P. E. Bader; L. E. Kandalaft et al. 

Acs Applied Bio Materials. 2021. Vol. 4, num. 12, p. 8291 – 8300. DOI : 10.1021/acsabm.1c00828.

Polymer Nanoparticle-Mediated Delivery of Oxidized Tumor Lysate-Based Cancer Vaccines

C. Berti; M. Graciotti; A. Boarino; C. Yakkala; L. E. Kandalaft et al. 

Macromolecular Bioscience. 2021.  p. 2100356. DOI : 10.1002/mabi.202100356.

Polymethylene Brushes via Surface-Initiated C1 Polyhomologation

F. Li; S. Thiele; H-A. Klok 

Journal Of The American Chemical Society. 2021. Vol. 143, num. 47, p. 19873 – 19880. DOI : 10.1021/jacs.1c09187.

Covalent and Noncovalent Conjugation of Degradable Polymer Nanoparticles to T Lymphocytes

T. Thomsen; R. Reissmann; E. Kaba; B. Engelhardt; H-A. Klok 

Biomacromolecules. 2021. Vol. 22, num. 8, p. 3416 – 3430. DOI : 10.1021/acs.biomac.1c00488.

Succinimidyl Carbonate-Based Amine-Reactive Polymer Brushes: Facile Fabrication of Functional Interfaces

T. N. Gevrek; A. Degirmenci; R. Sanyal; H-A. Klok; A. Sanyal 

Acs Applied Polymer Materials. 2021. Vol. 3, num. 5, p. 2507 – 2517. DOI : 10.1021/acsapm.1c00107.

Self-assembly of protein-polymer conjugates for drug delivery

C. A. Stevens; K. Kaur; H-A. Klok 

Advanced Drug Delivery Reviews. 2021. Vol. 174, p. 447 – 460. DOI : 10.1016/j.addr.2021.05.002.

A minimalistic cyclic ice-binding peptide from phage display

C. A. Stevens; F. Bachtiger; X. Kong; L. A. Abriata; G. C. Sosso et al. 

Nature Communications. 2021. Vol. 12, num. 1, p. 2675. DOI : 10.1038/s41467-021-22883-w.

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

S. Guo; T. D. R. Vance; H. Zahiri; R. Eves; C. A. Stevens et al. 

Mbio. 2021. Vol. 12, num. 2, p. e00130 – 21. DOI : 10.1128/mBio.00130-21.

Biotin-NeutrAvidin Mediated Immobilization of Polymer Micro- and Nanoparticles on T Lymphocytes

M. Ayer; O. Burri; R. Guiet; A. Seitz; E. Kaba et al. 

Bioconjugate Chemistry. 2021. Vol. 32, num. 3, p. 541 – 552. DOI : 10.1021/acs.bioconjchem.1c00026.

Chemical Cell Surface Modification and Analysis of Nanoparticle-Modified Living Cells

T. Thomsen; H-A. Klok 

Acs Applied Bio Materials. 2021. Vol. 4, num. 3, p. 2293 – 2306. DOI : 10.1021/acsabm.0c01619.

Enhancing T-cell response in cancer immunotherapy using nanoparticles

C. Berti / H-A. Klok (Dir.)  

Lausanne, EPFL, 2021. 

Mechanical Activation of Chemical Bonds at Polymer Interfaces

J. N. Bleich / H-A. Klok (Dir.)  

Lausanne, EPFL, 2021. 

Fluorescence-Based and Fluorescent Label-Free Characterization of Polymer Nanoparticle Decorated T Cells

T. Thomsen; A. B. Ayoub; D. Psaltis; H-A. Klok 

Biomacromolecules. 2021. Vol. 22, num. 1, p. 190 – 200. DOI : 10.1021/acs.biomac.0c00969.

2020

T Cell-Mediated Transport of Polymer Nanoparticles across the Blood-Brain Barrier

M. Ayer; M. Schuster; I. Gruber; C. Blatti; E. Kaba et al. 

Advanced Healthcare Materials. 2020.  p. 2001375. DOI : 10.1002/adhm.202001375.

Reversibly Cross-Linking Polymer Brushes Using Interchain Disulfide Bonds

P. Mocny; H-A. Klok 

Macromolecules. 2020. Vol. 53, num. 231, p. 731 – 740. DOI : 10.1021/acs.macromol.9b02199.

Light-Activated, Bioadhesive, Poly(2-hydroxyethyl methacrylate) Brush Coatings

J. Wang; P. Karami; N. C. Ataman; D. P. Pioletti; T. W. J. Steele et al. 

Biomacromolecules. 2020. Vol. 21, num. 1, p. 240 – 249. DOI : 10.1021/acs.biomac.9b01196.

Chemistry and Analysis of Nanoparticle-Modified Living Cells

T. Thomsen / H-A. Klok (Dir.)  

Lausanne, EPFL, 2020. 

Surface engineering of T cells with polymer nanoparticles to enhance drug delivery to the brain

M. Schuster / H-A. Klok (Dir.)  

Lausanne, EPFL, 2020. 

Functional and Responsive Polymers via Controlled Radical Polymerization

J. Wang / H-A. Klok (Dir.)  

Lausanne, EPFL, 2020. 

Complex polymer topologies and polymer-nanoparticle hybrid films prepared via surface-initiated controlled radical polymerization

P. Mocny; H-A. Klok 

Progress In Polymer Science. 2020. Vol. 100, p. 101185. DOI : 10.1016/j.progpolymsci.2019.101185.

2019

Synthesis of Loop Poly(Methyl Methacrylate) Brushes via Chain-End Postpolymerization Modification

P. Mocny; M. Menetrey; H-A. Klok 

Macromolecules. 2019. Vol. 52, num. 21, p. 8394 – 8403. DOI : 10.1021/acs.macromol.9b01527.

Mechanoresponsive Micro- and Nanoparticles

F. K. Metze; H-A. Klok 

Chimia. 2019. Vol. 73, num. 1, p. 35 – 38. DOI : 10.2533/chimia.2019.35.

Controlling topology, dynamics and function of polymer brushes via post-polymerization modification

P. Mocny / H-A. Klok (Dir.)  

Lausanne, EPFL, 2019. 

Polymer brush interfaces for protein biosensing prepared by surface-initiated controlled radical polymerization

M. Badoux; M. Billing; H-A. Klok 

Polymer Chemistry. 2019. Vol. 10, num. 23, p. 2925 – 2951. DOI : 10.1039/C9PY00163H.

Swelling-Induced Chain Stretching Enhances Hydrolytic Degrafting of Hydrophobic Polymer Brushes in Organic Media

J. Wang; H-A. Klok 

Angewandte Chemie International Edition. 2019. Vol. 58, p. 1 – 6. DOI : 10.1002/anie.201904436.

Future Directions at the Frontier of Polymer Science and Biology

S. Lecommandoux; H-A. Klok; Z. Zhong; T. J. Deming 

Biomacromolecules. 2019. Vol. 20, num. 1, p. 1 – 3. DOI : 10.1021/acs.biomac.8b01785.

Cellular Uptake and Intracellular Trafficking of Poly(N-(2-Hydroxypropyl) Methacrylamide)

C. Battistella; R. Guiet; O. Burri; A. Seitz; S. Escrig et al. 

Biomacromolecules. 2019. Vol. 20, num. 1, p. 231 – 242. DOI : 10.1021/acs.biomac.8b01372.

2018

Polymers at Interfaces

H. Klok 

2018. 256th National Meeting and Exposition of the American-Chemical-Society (ACS) – Nanoscience, Nanotechnology and Beyond, Boston, MA, Aug 19-23, 2018.

Trace element and isotope labels to study uptake and intracellular trafficking of polymer conjugates

H. Klok 

2018. 256th National Meeting and Exposition of the American-Chemical-Society (ACS) – Nanoscience, Nanotechnology and Beyond, Boston, MA, Aug 19-23, 2018.

Structure and functionality of polyelectrolyte brushes, a surface force perspective

X. Xu; M. Billing; M. Ruths; H-A. Klok; J. Yu 

Chemistry – An Asian Journal. 2018. Vol. 13, num. 22, p. 3411 – 3436. DOI : 10.1002/asia.201800920.

An Acid Test: Facile SI-ARGET-ATRP of Methacrylic Acid

T. D. Michl; D. Jung; A. Pertoldi; A. Schulte; P. Mocny et al. 

Macromolecular Chemistry and Physics. 2018. Vol. 219, num. 15, p. 1800182. DOI : 10.1002/macp.201800182.

Synthesis and Postpolymerization Modification of Fluorine-End-Labeled Poly(Pentafluorophenyl Methacrylate) Obtained via RAFT Polymerization

C. Battistella; Y. Yang; J. Chen; H-A. Klok 

Acs Omega. 2018. Vol. 3, num. 8, p. 9710 – 9721. DOI : 10.1021/acsomega.8b01654.

Polymers from Nature and for Nature

H. Sun; H-A. Klok; Z. Zhong 

Biomacromolecules. 2018. Vol. 19, num. 6, p. 1697 – 1700. DOI : 10.1021/acs.biomac.8b00830.

Stimuli-Sensitive and -Responsive Polymer Biomaterials

T. W. J. Steele; H-A. Klok 

Biomacromolecules. 2018. Vol. 19, num. 5, p. 1375 – 1377. DOI : 10.1021/acs.biomac.8b00145.

pH-Sensitive Coiled-Coil Peptide-Cross-Linked Hyaluronic Acid Nanogels: Synthesis and Targeted Intracellular Protein Delivery to CD44 Positive Cancer Cells

L. Ding; Y. Jiang; J. Zhang; H-A. Klok; Z. Zhong 

Biomacromolecules. 2018. Vol. 19, num. 2, p. 555 – 562. DOI : 10.1021/acs.biomac.7b01664.

Surface modification of living cells with synthetic polymer nano- and microparticles

H. Klok 

2018. 

Polymers at the Interface with Biology

T. Deming; H-A. Klok; S. Armes; M. Becker; J. Champion et al. 

Biomacromolecules. 2018. Vol. 19, num. 8, p. 3151 – 3162. DOI : 10.1021/acs.biomac.8b01029.

Polymer-Brush-Templated Three-Dimensional Molybdenum Sulfide Catalyst for Hydrogen Evolution

L-A. Stern; P. Mocny; H. Vrubel; T. Bilgic; H-A. Klok et al. 

ACS Applied Materials & Interfaces. 2018. Vol. 10, num. 7, p. 6253 – 6261. DOI : 10.1021/acsami.7b16679.

2017

Cell-mediated delivery of synthetic nano- and microparticles funding

M. Ayer; H-A. Klok 

Journal of Controlled Release. 2017. Vol. 259, p. 92 – 104. DOI : 10.1016/j.jconrel.2017.01.048.

T-cell surface modification with synthetic nanomaterials for cell-mediated delivery to the central nervous system

M. Ayer / H-A. Klok (Dir.)  

Lausanne, EPFL, 2017. 

Controlling and Monitoring Intracellular Drug Delivery Using PHPMA-Based Polymer Nanomedicines

C. Battistella / H-A. Klok (Dir.)  

Lausanne, EPFL, 2017. 

Controlling and Monitoring Intracellular Delivery of Anticancer Polymer Nanomedicines

C. Battistella; H-A. Klok 

Macromolecular Bioscience. 2017. Vol. 17, num. 10, p. 1700022. DOI : 10.1002/mabi.201700022.

The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

M. Graciotti; C. Berti; H-A. Klok; L. Kandalaft 

Journal Of Translational Medicine. 2017. Vol. 15, p. 142. DOI : 10.1186/s12967-017-1244-2.

Microcomputed Tomography Technique for In Vivo Three-Dimensional Fat Tissue Volume Evaluation After Polymer Injection

S. Berndt; I. Konz; D. Colin; S. Germain; B. Pittet-Cuenod et al. 

Tissue Engineering Part C-Methods. 2017. Vol. 23, num. 12, p. 964 – 970. DOI : 10.1089/ten.tec.2017.0207.

Surface-Initiated Controlled Radical Polymerization: State-of-the-Art, Opportunities, and Challenges in Surface and Interface Engineering with Polymer Brushes

J. O. Zoppe; N. C. Ataman; P. Mocny; J. Wang; J. Moraes et al. 

Chemical Reviews. 2017. Vol. 117, num. 3, p. 1105 – 1318. DOI : 10.1021/acs.chemrev.6b00314.

Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

C. Battistella; H-A. Klok 

Biomacromolecules. 2017. Vol. 18, num. 6, p. 1855 – 1865. DOI : 10.1021/acs.biomac.7b00291.

Site-Specific Polymer Attachment to HR2 Peptide Fusion Inhibitors against HIV-1 Decreases Binding Association Rates and Dissociation Rates Rather Than Binding Affinity

M. Danial; A. N. Stauffer; F. R. Wurm; M. J. Root; H-A. Klok 

Bioconjugate Chemistry. 2017. Vol. 28, num. 3, p. 701 – 712. DOI : 10.1021/acs.bioconjchem.6b00540.

Peptide-Enhanced Selective Surface Deposition of Polymer-Based Fragrance Delivery Systems

K. A. Guenay; D. Benczedi; A. Herrmann; H-A. Klok 

Advanced Functional Materials. 2017. Vol. 27, num. 2, p. 1603843. DOI : 10.1002/adfm.201603843.

Cellulose Nanocrystals with Tethered Polymer Chains: Chemically Patchy versus Uniform Decoration

J. O. Zoppe; A. V. M. Dupire; T. G. G. Lachat; P. Lemal; L. Rodriguez-Lorenzo et al. 

ACS Macro Letters. 2017. Vol. 6, num. 9, p. 892 – 897. DOI : 10.1021/acsmacrolett.7b00383.

Selective Peptide-Mediated Enhanced Deposition of Polymer Fragrance Delivery Systems on Human Hair

K. A. Gunay; D. L. Berthier; H. K. Jerri; D. Benczedi; H-A. Klok et al. 

ACS Applied Materials & Interfaces. 2017. Vol. 9, num. 28, p. 24238 – 24249. DOI : 10.1021/acsami.7b06569.

Caspofungin on ARGET-ATRP grafted PHEMA polymers: Enhancement and selectivity of prevention of attachment of Candida albicans

T. D. Michl; C. Giles; P. Mocny; K. Futrega; M. R. Doran et al. 

Biointerphases. 2017. Vol. 12, num. 5, p. 05G602. DOI : 10.1116/1.4986054.

2016

Tribology of surface-grafted polymer brushes

P. Mocny; H-A. Klok 

Molecular Systems Design & Engineering. 2016. Vol. 1, num. 2, p. 141 – 154. DOI : 10.1039/c5me00010f.

Swelling Behavior and Nanomechanical Properties of (Peptide-Modified) Poly(2-hydroxyethyl methacrylate) and Poly(poly(ethylene glycol) methacrylate) Brushes

S. Desseaux; J. P. Hinestrosa; N. Schuwer; B. S. Lokitz; J. F. Ankner et al. 

Macromolecules. 2016. Vol. 49, num. 12, p. 4609 – 4618. DOI : 10.1021/acs.macromol.6b00881.

Effect of Surface Charge on Surface-Initiated Atom Transfer Radical Polymerization from Cellulose Nanocrystals in Aqueous Media

J. O. Zoppe; X. Xu; C. Kaenel; P. Orsolini; G. Siqueira et al. 

Biomacromolecules. 2016. Vol. 17, num. 4, p. 1404 – 1413. DOI : 10.1021/acs.biomac.6b00011.

Effects of Grafting Density and Film Thickness on the Adhesion of Staphylococcus epidermidis to Poly(2-hydroxy ethyl methacrylate) and Poly(poly(ethylene glycol)methacrylate) Brushes

S-A. Ibanescu; J. Nowakowska; N. Khanna; R. Landmann; H-A. Klok 

Macromolecular Bioscience. 2016. Vol. 16, num. 5, p. 676 – 685. DOI : 10.1002/mabi.201500335.

Click Chemistry in Biomaterials, Nanomedicine, and Drug Delivery

K. S. Anseth; H-A. Klok 

Biomacromolecules. 2016. Vol. 17, num. 1, p. 1 – 3. DOI : 10.1021/acs.biomac.5b01660.

Impact of polymer-modified gold nanoparticles on brain endothelial cells: exclusion of endoplasmic reticulum stress as a potential risk factor

L. Anspach; R. E. Unger; C. Brochhausen; M. I. Gibson; H-A. Klok et al. 

Nanotoxicology. 2016. Vol. 10, num. 9, p. 1341 – 1350. DOI : 10.1080/17435390.2016.1214761.

Bioinspired Selective Surface Deposition of Fragrance Delivery Systems

K. A. Günay / H-A. Klok (Dir.)  

Lausanne, EPFL, 2016. 

Mechanochemically Responsive Surfaces and Soft Tissue Adhesive Interfaces Generated via Controlled Radical Polymerization

N. Çavuşoǧlu Ataman / H-A. Klok (Dir.)  

Lausanne, EPFL, 2016. 

Synthesis of cyclic peptide disulfide-PHPMA conjugates via sequential active ester aminolysis and CuAAC coupling

K. A. Guenay; H-A. Klok 

Polymer Chemistry. 2016. Vol. 7, num. 4, p. 970 – 978. DOI : 10.1039/c5py01817j.

Degrafting of Poly(poly(ethylene glycol) methacrylate) Brushes from Planar and Spherical Silicon Substrates

N. C. Ataman; H-A. Klok 

Macromolecules. 2016. Vol. 49, num. 23, p. 9035 – 9047. DOI : 10.1021/acs.macromol.6b01445.

Influence of Block versus Random Monomer Distribution on the Cellular Uptake of Hydrophilic Copolymers

J. Moraes; R. Peltier; G. Gody; M. Blum; S. Recalcati et al. 

ACS Macro Letters. 2016. Vol. 5, num. 12, p. 1416 – 1420. DOI : 10.1021/acsmacrolett.6b00652.

2015

Peptide-Polymer Conjugates for Therapeutic Applications

A. M. Răduţă / H-A. Klok (Dir.)  

Lausanne, EPFL, 2015. 

Polymer Brushes – Engineered Model Interfaces and Functional Surface Coatings for DNA Biosensing and Electrocatalysis

T. Bilgiç Tune / H-A. Klok (Dir.)  

Lausanne, EPFL, 2015. 

Shape-Persistent, Thermoresponsive Polypeptide Brushes Prepared by Vapor Deposition Surface-Initiated Ring-Opening Polymerization of alpha-Amino Acid N-Carboxyanhydrides

Y. Shen; S. Desseaux; B. Aden; B. S. Lokitz; Z. Li et al. 

Macromolecules. 2015. Vol. 48, num. 8, p. 2399 – 2406. DOI : 10.1021/acs.macromol.5b00017.

Polypeptide brushes grown via surface-initiated ring-opening polymerization of alpha-amino acid N-carboxyanhydrides

Y. Shen; Z. Li; H-A. Klok 

Chinese Journal Of Polymer Science. 2015. Vol. 33, num. 7, p. 931 – 946. DOI : 10.1007/s10118-015-1654-7.

Identification of Soft Matter Binding Peptide Ligands Using Phage Display

K. A. Guenay; H-A. Klok 

Bioconjugate Chemistry. 2015. Vol. 26, num. 10, p. 2002 – 2015. DOI : 10.1021/acs.bioconjchem.5b00377.

Polymer Brush Guided Formation of Conformal, Plasmonic Nanoparticle-Based Electrodes for Microwire Solar Cells

C. Sugnaux; A. D. Mallorqui; J. Herriman; H-A. Klok; A. Fontcuberta I Morral 

Advanced Functional Materials. 2015. Vol. 25, num. 25, p. 3958 – 3965. DOI : 10.1002/adfm.201404235.

Expanding the Polymer Mechanochemistry Toolbox through Surface-Initiated Polymerization

H-A. Klok; J. Genzer 

ACS Macro Letters. 2015. Vol. 4, num. 6, p. 636 – 639. DOI : 10.1021/acsmacrolett.5b00295.

Avoiding compositional drift during the RAFT copolymerization of N-(2-hydroxypropyl)-methacrylamide and N-acryloxysuccinimide: towards uniform platforms for post-polymerization modification (vol 6, pg 3245, 2015)

J. Moraes; I-M. Simionca; H. Ketari; H-A. Klok 

Polymer Chemistry. 2015. Vol. 6, num. 42, p. 7480 – 7483. DOI : 10.1039/c5py90156a.

Polymeric Anti-HIV Therapeutics

M. Danial; H-A. Klok 

Macromolecular Bioscience. 2015. Vol. 15, num. 1, p. 9 – 35. DOI : 10.1002/mabi.201400298.

Oligonucleotide Immobilization and Hybridization on Aldehyde-Functionalized Poly(2-hydroxyethyl methacrylate) Brushes

T. Bilgic; H-A. Klok 

Biomacromolecules. 2015. Vol. 16, num. 11, p. 3657 – 3665. DOI : 10.1021/acs.biomac.5b01116.

Glucose Monitoring Using a Polymer Brush Modified Polypropylene Hollow Fiber-based Hydraulic Flow Sensor

N. Fortin; H-A. Klok 

Acs Applied Materials & Interfaces. 2015. Vol. 7, num. 8, p. 4631 – 4640. DOI : 10.1021/am507927w.

Surface-initiated controlled radical polymerization enhanced DNA biosensing

T. Bilgic; H-A. Klok 

European Polymer Journal. 2015. Vol. 62, p. 281 – 293. DOI : 10.1016/j.eurpolymj.2014.07.037.

Fibroblast adhesion on ECM-derived peptide modified poly(2-hydroxyethyl methacrylate) brushes: Ligand co-presentation and 3D-localization

S. Desseaux; H-A. Klok 

Biomaterials. 2015. Vol. 44, p. 24 – 35. DOI : 10.1016/j.biomaterials.2014.12.011.

Surface Grafted Polymer Brushes : A Versatile Platform for Antibacterial Applications

S. A. Ibanescu / H-A. Klok (Dir.)  

Lausanne, EPFL, 2015. 

Avoiding compositional drift during the RAFT copolymerization of N-(2-hydroxypropyl)methacrylamide and N-acryloxysuccinimide: towards uniform platforms for post-polymerization modification

J. Moraes; I-M. Simionca; H. Ketari; H-A. Klok 

Polymer Chemistry. 2015. Vol. 6, num. 17, p. 3245 – 3251. DOI : 10.1039/c5py00253b.

2014

Gating, sensing and templating with polymer brushes

C. Sugnaux / H-A. Klok (Dir.)  

Lausanne, EPFL, 2014. 

Temperature-Controlled Masking/Unmasking of Cell-Adhesive Cues with Poly(ethylene glycol) Methacrylate Based Brushes

S. Desseaux; H-A. Klok 

Biomacromolecules. 2014. Vol. 15, num. 10, p. 3859 – 3865. DOI : 10.1021/bm501233h.

Copolymerization of 2,2,3,3,4,4,4-heptafluorobutyl acrylate with butyl acrylate via RAFT polymerization

B. P. Koiry; H-A. Klok; N. K. Singha 

Journal Of Fluorine Chemistry. 2014. Vol. 165, p. 109 – 115. DOI : 10.1016/j.jfluchem.2014.06.016.

Controlled release from a mechanically-stimulated thermosensitive self-heating composite hydrogel

M. Nassajian Moghadam; V. Kolesov; H-A. Klok; D. Pioletti 

Biomaterials. 2014. Vol. 35, p. 450 – 455. DOI : 10.1016/j.biomaterials.2013.09.065.

Maleimide-Functionalized Thiol Reactive Copolymer Brushes: Fabrication and Post-Polymerization Modification

T. N. Gevrek; T. Bilgic; H-A. Klok; A. Sanyal 

Macromolecules. 2014. Vol. 47, num. 22, p. 7842 – 7851. DOI : 10.1021/ma5015098.

Squaric acid mediated bioconjugation expanded to polymers prepared by ATRP

T. Steinbach; F. Wurm; H-A. Klok 

Polymer Chemistry. 2014. Vol. 5, num. 13, p. 4039 – 4047. DOI : 10.1039/c4py00168k.

Modulating Cell-Surface Interactions with Polymer Brushes

S. Desseaux / H-A. Klok; K. Voitchovsky (Dir.)  

Lausanne, EPFL, 2014. 

Functional polypeptide and hybrid materials: Precision synthesis via alpha-amino acid N-carboxyanhydride polymerization and emerging biomedical applications

C. Deng; J. Wu; R. Cheng; F. Meng; H-A. Klok et al. 

Progress In Polymer Science. 2014. Vol. 39, num. 2, p. 330 – 364. DOI : 10.1016/j.progpolymsci.2013.10.008.

Polymer Brush Gradients Grafted from Plasma-Polymerized Surfaces

B. R. Coad; T. Bilgic; H-A. Klok 

Langmuir. 2014. Vol. 30, num. 28, p. 8357 – 8365. DOI : 10.1021/la501380m.

Responsive polymer and peptide-polymer hybrid microgels

V. Kolesov / H-A. Klok (Dir.)  

Lausanne, EPFL, 2014. 

Poly[N-(2-hydroxypropyl)methacrylamide] nanogels by RAFT polymerization in inverse emulsion

H. Wutzel; F. H. Richter; Y. Li; S. S. Sheiko; H-A. Klok 

Polymer Chemistry. 2014. Vol. 5, num. 5, p. 1711 – 1719. DOI : 10.1039/c3py01280h.

Glucose-Sensitive QCM-Sensors Via Direct Surface RAFT Polymerization

C. Sugnaux; H-A. Klok 

Macromolecular Rapid Communications. 2014. Vol. 35, num. 16, p. 1402 – 1407. DOI : 10.1002/marc.201400217.

2013

Postpolymerization Modification of Poly(glycidyl methacrylate) Brushes: An XPS Depth-Profiling Study

R. Barbey; V. Laporte; S. Alnabulsi; H-A. Klok 

Macromolecules. 2013. Vol. 46, num. 15, p. 6151 – 6158. DOI : 10.1021/ma400819a.

Aqueous Fabrication of pH-Gated, Polymer-Brush-Modified Alumina Hybrid Membranes

C. Sugnaux; L. Lavanant; H-A. Klok 

Langmuir. 2013. Vol. 29, num. 24, p. 7325 – 7333. DOI : 10.1021/la304949h.

Be squared: expanding the horizon of squaric acid-mediated conjugations

F. R. Wurm; H-A. Klok 

Chemical Society Reviews. 2013. Vol. 42, num. 21, p. 8220 – 8236. DOI : 10.1039/c3cs60153f.

Standing on the shoulders of hermann staudinger: Post-polymerization modification from past to present

K. A. Guenay; P. Theato; H-A. Klok 

Journal Of Polymer Science Part A-Polymer Chemistry. 2013. Vol. 51, num. 1, p. 1 – 28. DOI : 10.1002/pola.26333.

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

R. Cheng; F. Meng; C. Deng; H-A. Klok; Z. Zhong 

Biomaterials. 2013. Vol. 34, num. 14, p. 3647 – 3657. DOI : 10.1016/j.biomaterials.2013.01.084.

One-pot squaric acid diester mediated aqueous protein conjugation

F. Wurm; T. Steinbach; H-A. Klok 

Chemical Communications. 2013. Vol. 49, num. 71, p. 7815 – 7817. DOI : 10.1039/c3cc44039g.

Multifaceted polymer coated, gold nanoparticles

L. Chen; H-A. Klok 

Soft Matter. 2013. Vol. 9, num. 45, p. 10678 – 10688. DOI : 10.1039/c3sm51789f.

Towards the Synthesis of Uniform Polymers by Template Polymerization

G. G. Sahin Kurtuldu / H-A. Klok (Dir.)  

Lausanne, EPFL, 2013. 

2012

Osteoconductive surfaces generated from peptide functionalized poly(2-hydroxyethyl methacrylate-co-2-(methacryloyloxy)ethyl phosphate) brushes

D. Paripovic; H. Hall-Bozic; H-A. Klok 

Journal Of Materials Chemistry. 2012. Vol. 22, num. 37, p. 19570 – 19578. DOI : 10.1039/c2jm31568h.

Squaric Acid Mediated Synthesis and Biological Activity of a Library of Linear and Hyperbranched Poly(Glycerol)-Protein Conjugates

F. Wurm; C. Dingels; H. Frey; H-A. Klok 

Biomacromolecules. 2012. Vol. 13, p. 1161 – 1171. DOI : 10.1021/bm300103u.

Size- and Coating-Dependent Uptake of Polymer-Coated Gold Nanoparticles in Primary Human Dermal Microvascular Endothelial Cells

C. Freese; M. I. Gibson; H-A. Klok; R. E. Unger; C. J. Kirkpatrick 

Biomacromolecules. 2012. Vol. 13, p. 1533 – 1543. DOI : 10.1021/bm300248u.

Poly(ethyleneimine)-Mediated Large-Scale Transient Gene Expression: Influence of Molecular Weight, Polydispersity and N-Propionyl Groups

Z. Kadlecova; S. Nallet; D. L. Hacker; L. Baldi; H-A. Klok et al. 

Macromolecular Bioscience. 2012. Vol. 12, p. 628 – 636. DOI : 10.1002/mabi.201100404.

Comparative Study on the In Vitro Cytotoxicity of Linear, Dendritic, and Hyperbranched Polylysine Analogues

Z. Kadlecova; L. Baldi; D. Hacker; F. M. Wurm; H-A. Klok 

Biomacromolecules. 2012. Vol. 13, num. 10, p. 3127 – 3137. DOI : 10.1021/bm300930j.

Squaric Acid Mediated Chemoselective PEGylation of Proteins: Reactivity of Single-Step-Activated alpha-Amino Poly(ethylene glycol)s

C. Dingels; F. Wurm; M. Wagner; H-A. Klok; H. Frey 

Chemistry-A European Journal. 2012. Vol. 18, num. 52, p. 16828 – 16835. DOI : 10.1002/chem.201200182.

Synthesis and post-polymerization modification of poly(pentafluorophenyl methacrylate) brushes

K. A. Guenay; N. Schuewer; H-A. Klok 

Polymer Chemistry. 2012. Vol. 3, p. 2186 – 2192. DOI : 10.1039/c2py20162c.

Polyvalent Side Chain Peptide-Synthetic Polymer Conjugates as HIV-1 Entry Inhibitors

M. Danial; M. J. Root; H-A. Klok 

Biomacromolecules. 2012. Vol. 13, p. 1438 – 1447. DOI : 10.1021/bm300150q.

Voltammetric Detection of Hg2+ Using Peptide-Functionalized Polymer Brushes

N. Schuewer; M-L. Tercier-Waeber; M. Danial; H-A. Klok 

Australian Journal Of Chemistry. 2012. Vol. 65, num. 8, p. 1104 – 1109. DOI : 10.1071/Ch12177.

Site-Specific PEGylation of HR2 Peptides: Effects of PEG Conjugation Position and Chain Length on HIV-1 Membrane Fusion Inhibition and Proteolytic Degradation

M. Danial; V. Dulmen; H. H. Tim; J. Aleksandrowicz; A. J. G. Poetgens et al. 

Bioconjugate Chemistry. 2012. Vol. 23, num. 8, p. 1648 – 1660. DOI : 10.1021/bc3002248.

Hyperbranched Polylysine: A Versatile, Biodegradable Transfection Agent for the Production of Recombinant Proteins by Transient Gene Expression and the Transfection of Primary Cells

Z. Kadlecova; Y. Rajendra; M. Matasci; D. Hacker; L. Baldi et al. 

Macromolecular Bioscience. 2012. Vol. 12, p. 794 – 804. DOI : 10.1002/mabi.201100519.

Assessment of transferrin recycling by Triplet Lifetime Imaging in living cells

M. Geissbuehler; Z. Kadlecova; H-A. Klok; T. Lasser 

Biomedical Optics Express. 2012. Vol. 3, num. 10, p. 2526 – 2536. DOI : 10.1364/BOE.3.002526.

Functional, Hyperbranched Polyesters Via Baylis-Hillman Polymerization

S. Ji; B. Bruchmann; F. Wurm; H-A. Klok 

Journal Of Polymer Science Part A-Polymer Chemistry. 2012. Vol. 50, p. 25 – 34. DOI : 10.1002/pola.24954.

2011

Aqueous solution self-assembly of polystyrene-b-poly(L-lysine) diblock oligomers

H. Nuhn; H-A. Klok 

European Polymer Journal. 2011. Vol. 47, p. 782 – 791. DOI : 10.1016/j.eurpolymj.2010.09.026.

Side-Chain Peptide-Synthetic Polymer Conjugates via Tandem “Ester-Amide/Thiol-Ene” Post-Polymerization Modification of Poly(pentafluorophenyl methacrylate) Obtained Using ATRP

N. K. Singha; M. I. Gibson; B. P. Koiry; M. Danial; H-A. Klok 

Biomacromolecules. 2011. Vol. 12, p. 2908 – 2913. DOI : 10.1021/bm200469a.

Tuning the pH Sensitivity of Poly(methacrylic acid) Brushes

N. Schuewer; H-A. Klok 

Langmuir. 2011. Vol. 27, p. 4789 – 4796. DOI : 10.1021/la200347u.

Synthesis of Responsive Polymer Brushes for Sensing Applications

N. B. Schüwer / H-A. Klok (Dir.)  

Lausanne, EPFL, 2011. 

Combating HIV Type 1 with Peptide – Synthetic Polymer Conjugates

M. Danial / H-A. Klok (Dir.)  

Lausanne, EPFL, 2011. 

Arginine-specific protein modification using alpha-oxo-aldehyde functional polymers prepared by atom transfer radical polymerization

M. A. Gauthier; M. Ayer; J. Kowal; F. R. Wurm; H-A. Klok 

Polymer Chemistry. 2011. Vol. 2, p. 1490 – 1498. DOI : 10.1039/c0py00422g.

Synthesis of Functional Polyesters via Baylis-Hillman Polymerization

S. Ji / H-A. Klok (Dir.)  

Lausanne, EPFL, 2011. 

Synthesis of Side-Chain Functional Polyesters via Baylis-Hillman Polymerization

S. Ji; B. Bruchmann; H-A. Klok 

Macromolecules. 2011. Vol. 44, p. 5218 – 5226. DOI : 10.1021/ma2006238.

Improving the Stability in Aqueous Media of Polymer Brushes Grafted from Silicon Oxide Substrates by Surface-Initiated Atom Transfer Radical Polymerization

D. Paripovic; H-A. Klok 

Macromolecular Chemistry And Physics. 2011. Vol. 212, p. 950 – 958. DOI : 10.1002/macp.201000729.

Neutron Reflectivity Study on the Postpolymerization Modification of Poly(2-hydroxyethyl methacrylate) Brushes

N. Schuewer; T. Geue; J. P. Hinestrosa; H-A. Klok 

Macromolecules. 2011. Vol. 44, p. 6868 – 6874. DOI : 10.1021/ma201069d.

Exploring the Scope of the Baylis-Hillman Reaction for the Synthesis of Side-Chain Functional Polyesters

S. Ji; B. Bruchmann; H-A. Klok 

Macromolecular Chemistry And Physics. 2011. Vol. 212, p. 2612 – 2618. DOI : 10.1002/macp.201100482.

Arginine-Specific Modification of Proteins with Polyethylene Glycol

M. A. Gauthier; H-A. Klok 

Biomacromolecules. 2011. Vol. 12, num. 2, p. 482 – 493. DOI : 10.1021/bm101272g.

Polymer Coiled-Coil Conjugates: Potential for Development as a New Class of Therapeutic “Molecular Switch”

S. P. E. Deacon; B. Apostolovic; R. J. Carbajo; A-K. Schott; K. Beck et al. 

Biomacromolecules. 2011. Vol. 12, num. 1, p. 19 – 27. DOI : 10.1021/bm100843e.

Assessing the cellular uptake pathway for poly-Lysine analogues using triplet lifetime imaging

M. Geissbuehler; Z. Kadlecova; I. Märki; M. Matasci; D. Van De Ville et al. 

Biophysical Society 55th Annual Meeting, Baltimore, Maryland, USA, March 5-9, 2011.

Interactive Surfaces Based on Polymer Brushes

D. Paripovic / H-A. Klok (Dir.)  

Lausanne, EPFL, 2011. 

Polymers Interfacing with Biology

F. Wurm; H-A. Klok 

Chimia. 2011. Vol. 65, p. 659 – 662. DOI : 10.2533/chimia.2011.659.

Conformational consequences of cooperative binding of a coiled-coil peptide motif to poly(N-(2-hydroxypropyl) methacrylamide) HPMA copolymers

P. C. Griffiths; A. Paul; B. Apostolovic; H-A. Klok; E. de Luca et al. 

Journal Of Controlled Release. 2011. Vol. 153, p. 173 – 179. DOI : 10.1016/j.jconrel.2011.03.030.

Diagnostic and Sensory Polymer Brushes

N. Schuewer; R. Barbey; H-A. Klok 

Chimia. 2011. Vol. 65, p. 276 – 276. DOI : 10.2533/chimia.2011.276.

Gene Delivery with Hyperbranched Polylysine

Z. Kadlecova / H-A. Klok (Dir.)  

Lausanne, EPFL, 2011. 

Sequentially Modified, Polymer-Stabilized Gold Nanoparticle Libraries: Convergent Synthesis and Aggregation Behavior

M. I. Gibson; M. Danial; H-A. Klok 

Acs Combinatorial Science. 2011. Vol. 13, p. 286 – 297. DOI : 10.1021/co100099r.

Cell Uptake and Trafficking Behavior of Non-covalent, Coiled-coil Based Polymer-Drug Conjugates

B. Apostolovic; S. P. E. Deacon; R. Duncan; H-A. Klok 

Macromolecular Rapid Communications. 2011. Vol. 32, num. 1, p. 11 – 18. DOI : 10.1002/marc.201000434.

2010

Coiled coils: attractive protein folding motifs for the fabrication of self-assembled, responsive and bioactive materials

B. Apostolovic; M. Danial; H-A. Klok 

Chemical Society Reviews. 2010. Vol. 39, num. 9, p. 3541. DOI : 10.1039/b914339b.

Synthesis of Functional Polydepsipeptides via Direct Ring-Opening Polymerization and Post-Polymerization Modification

N. Franz; H-A. Klok 

Macromolecular Chemistry and Physics. 2010. Vol. 211, num. 7, p. 809 – 820. DOI : 10.1002/macp.200900521.

A Potassium-Selective Quartz Crystal Microbalance Sensor Based on Crown-Ether Functionalized Polymer Brushes

N. Schüwer; H-A. Klok 

Advanced Materials. 2010. Vol. 22, num. 30, p. 3251 – 3255. DOI : 10.1002/adma.201000377.

Copolymerization Behavior of N-(2-Hydroxypropyl)methacrylamide and methacrylated coiled-coil peptide derivative

B. Apostolovic; H-A. Klok 

Biomacromolecules. 2010. Vol. 11, num. 7, p. 1891 – 1895. DOI : 10.1021/bm100533g.

Polymer Brushes as Substrates for Microarray Applications

R. Barbey / H-A. Klok (Dir.)  

Lausanne, EPFL, 2010. 

Hybrid Polymer Therapeutics Incorporating Bioresponsive, Coiled Coil Peptide Linkers

B. Apostolovic; S. P. E. Deacon; R. Duncan; H-A. Klok 

Biomacromolecules. 2010. Vol. 11, num. 5, p. 1187 – 1195. DOI : 10.1021/bm901313c.

Polymer Conjugates

H-A. Klok 

Macromolecular Rapid Communications. 2010. Vol. 31, num. 14, p. 1230 – 1230. DOI : 10.1002/marc.201000182.

Polymer–protein conjugates: an enzymatic activity perspective

M. A. Gauthier; H-A. Klok 

Polymer Chemistry. 2010. Vol. 1, num. 9, p. 1352 – 1373. DOI : 10.1039/c0py90001j.

Size-Dependent LCST Transitions of Polymer-Coated Gold Nanoparticles: Cooperative Aggregation and Surface Assembly

M. I. Gibson; D. Paripovic; H-A. Klok 

Advanced Materials. 2010. Vol. 22, num. 42, p. 4721 – 4725. DOI : 10.1002/adma.201001382.

Hybrid Polymer Therapeutics Incorporating Bioresponsive, Coiled Coil Peptide Linkers

B. Apostolovic / H-A. Klok (Dir.)  

Lausanne, EPFL, 2010. 

Room Temperature, Aqueous Post-Polymerization Modification of Glycidyl Methacrylate-Containing Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization

R. Barbey; H-A. Klok 

Langmuir. 2010. Vol. 26, num. 23, p. 18219 – 18230. DOI : 10.1021/la102400z.

A facile strategy for the modification of polyethylene substrates with non-fouling, bioactive poly(poly(ethylene glycol) methacrylate) brushes

L. Lavanant; B. Pullin; J. A. Hubbell; H-A. Klok 

Macromolecular bioscience. 2010. Vol. 10, num. 1, p. 101 – 8. DOI : 10.1002/mabi.200900205.

Protein Microarrays Based on Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization

R. Barbey; E. Kauffmann; M. Ehrat; H-A. Klok 

Biomacromolecules. 2010. Vol. 11, num. 12, p. 3467 – 3479. DOI : 10.1021/bm101297w.

2009

Synthesis of functional polymers by post-polymerization modification

M. A. Gauthier; M. I. Gibson; H-A. Klok 

Angewandte Chemie International Edition. 2009. Vol. 48, p. 48 – 58. DOI : 10.1002/anie.200801951.

Surface Modification of Polydimethylsiloxane Substrates with Nonfouling Poly(Poly(ethylene glycol)methacrylate) Brushes

S. Tugulu; H-A. Klok 

Macromolecular Symposia. 2009. Vol. 279, num. 1, p. 103 – 109. DOI : 10.1002/masy.200950516.

Polymer Brushes via Surface-Initiated Controlled Radical Polymerization: Synthesis, Characterization, Properties, and Applications

R. Barbey; L. Lavanant; D. Paripovic; N. Schüwer; C. Sugnaux et al. 

Chemical Reviews. 2009. Vol. 109, num. 11, p. 5437 – 5527. DOI : 10.1021/cr900045a.

Dendritic and hyperbranched polyamides

M. Scholl; Z. Kadlecova; H-A. Klok 

Progr. Polym. Sci. 2009. Vol. 34, p. 24 – 61. DOI : 10.1016/j.progpolymsci.2008.09.001.

Peptide/Protein−Synthetic Polymer Conjugates: Quo vadis

H-A. Klok 

Macromolecules. 2009. Vol. 42, num. 21, p. 7990 – 8000. DOI : 10.1021/ma901561t.

Synthesis of functional polymers by post-polymerization modification

M. A. Gauthier; M. I. Gibson; H-A. Klok 

Angewandte Chemie. 2009. Vol. 121, num. 1, p. 50 – 60. DOI : 10.1002/ange.200801951.

A post-modification approach to peptide foldamers

N. Franz; L. Menin; H-A. Klok 

Organic & Biomolecular Chemistry. 2009. Vol. 7, num. 24, p. 5207 – 5218. DOI : 10.1039/b912313j.

Nonfouling Polypeptide Brushes via Surface-initiated Polymerization of N-epsilon-oligo(ethylene glycol)succinate-L-lysine N-carboxyanhydride

J. Wang; M. I. Gibson; R. Barbey; S-J. Xiao; H-A. Klok 

Macromolecular Rapid Communications. 2009. Vol. 30, num. 9-10, p. 845 – 850. DOI : 10.1002/marc.200800744.

A Post-Modification Strategy for the Synthesis of Uniform, Hydrophilic/Hydrophobic Patterned α-Hydroxy Acid Oligomers

N. Franz; L. Menin; H-A. Klok 

European Journal of Organic Chemistry. 2009. num. 31, p. 5390 – 5405. DOI : 10.1002/ejoc.200900663.

Degradable Polymer Brushes Prepared via Surface-Initiated Controlled Radical Polymerization

C. Riachi; N. Schüwer; H-A. Klok 

Macromolecules. 2009. Vol. 42, num. 21, p. 8076 – 8081. DOI : 10.1021/ma901537x.

Synthesis of sequence-defined oligomers and polymers

N. Franz / H-A. Klok (Dir.)  

Lausanne, EPFL, 2009. 

Potential novel drug carriers for inner ear treatment: hyperbranched polylysine and lipid nanocapsules

V. Scheper; M. Wolf; M. Scholl; Z. Kadlecova; T. Perrier et al. 

Nanomedicine. 2009. Vol. 4, num. 6, p. 623 – 635. DOI : 10.2217/nnm.09.41.

Postpolymerization modification of poly(pentafluorophenyl methacrylate): Synthesis of a diverse water-soluble polymer library

M. I. Gibson; E. Fröhlich; H-A. Klok 

Journal of Polymer Science Part A: Polymer Chemistry. 2009. Vol. 47, num. 17, p. 4332 – 4345. DOI : 10.1002/pola.23486.

2008

Solution behavior of peptide and peptide-hybrid materials

H. Nuhn / H-A. Klok (Dir.)  

Lausanne, EPFL, 2008. 

pH-Sensitivity of the E3/K3 heterodimeric coiled coil

B. Apostolovic; H-A. Klok 

Biomacromolecules. 2008. Vol. 9, p. 3173 – 3180. DOI : 10.1021/bm800746e.

Investigation of the Release of Bioactive Volatiles from Amphiphilic Multiarm Star-Block Copolymers by Thermogravimetry and Dynamic Headspace Analysis

C. Ternat; L. Ouali; H. Sommer; W. Fieber; M. I. Velazco et al. 

Macromolecules. 2008. Vol. 41, p. 7079 – 7089. DOI : 10.1021/ma801366m.

Secondary structure formation and LCST behaviour of short, elastin-like peptides

H. Nuhn; H-A. Klok 

Biomacromolecules. 2008. Vol. 9, p. 2755 – 2763. DOI : 10.1021/bm800784y.

Peptide/protein – polymer conjugates: synthetic strategies and design concepts

M. A. Gauthier; H-A. Klok 

Chemical Communications. 2008. num. 23, p. 2591 – 2611. DOI : 10.1039/b719689j.

Stability and nonfouling properties of poly(poly(ethylene glycol) methacrylate) brushes under cell culture conditions

S. Tugulu; H-A. Klok 

Biomacromolecules. 2008. Vol. 9, p. 906 – 912. DOI : 10.1021/bm701293g.

Biofunctional and biomimetic polymer brushes prepared via surface-initiated atom transfer radical polymerization

L. Lavanant; H-A. Klok 

Chimia. 2008. Vol. 62, num. 10, p. 793 – 798. DOI : 10.2533/chimia.2008.793.

Self-organization on multiple length scales in “hairy rod”- coil block copolymer supramolecular complexes

M. R. Hammond; H-A. Klok; R. Mezzenga 

Macromol. Rapid. Commun. 2008. Vol. 29, p. 299 – 303. DOI : 10.1002/marc.200700666.

2007

Functional polymer brushes via surface-initiated controlled radical polymerizations

S. Tugulu / H-A. Klok (Dir.)  

Lausanne, EPFL, 2007. 

Complex coacervate core micelles with a lysozyme-modified corona

M. Danial; H-A. Klok; W. Norde; M. A. C. Stuart 

Langmuir. 2007. Vol. 23, num. 15, p. 8003 – 8009. DOI : 10.1021/la700573j.

Synthesis, structural characterization and applications of hyperbranched polymers based on L-lysine

M. T. Scholl / H-A. Klok (Dir.)  

Lausanne, EPFL, 2007. 

Synthesis of poly(methacrylic acid) brushes via surface-initiated atom transfer radical polymerization of sodium methacrylate and their use as substrates for the mineralization of calcium carbonate

S. Tugulu; R. Barbey; M. Harms; M. Fricke; D. Volkmer et al. 

Macromolecules. 2007. Vol. 40, num. 2, p. 168 – 177. DOI : 10.1021/ma060739e.

Macromolecular engineering of polypeptides using the ring-opening polymerization of alpha-amino acid N-carboxyanhydrides

H-A. Klok; T. Deming 

Macromolecular Engineering. Precise Synthesis, Materials Properties, Applications; Wiley-VCH Verlag, 2007. p. 519 – 540.

Controlling polymer architecture in the thermal hyperbranched polymerization of L-lysine

M. Scholl; T. Q. Nguyen; B. Bruchmann; H-A. Klok 

Macromolecules. 2007. Vol. 40, num. 16, p. 5726 – 5734. DOI : 10.1021/ma070494l.

Amphiphilic multi-arm star-block copolymers for encapsulation of fragrance molecules

C. Ternat; G. Kreutzer; C. J. Plummer; T. Q. Nguyen; A. Herrmann et al. 

Macromolecular Chemistry and Physics. 2007. Vol. 208, num. 2, p. 131 – 145. DOI : 10.1002/macp.200600449.

NMR diffusion and relaxation studies of the encapsulation of fragrances by amphiphilic multiarm star block copolymers

W. Fieber; A. Herrmann; L. Ouali; M. I. Velazco; G. Kreutzer et al. 

Macromolecules. 2007. Vol. 40, num. 15, p. 5372 – 5378. DOI : 10.1021/ma070222i.

Dark curing kinetics of UV printing inks by real-time ATR-FTIR spectroscopy

E. Nouzille / T. Q. Nguyen (Dir.)  

Lausanne, EPFL, 2007. 

RGD-Functionalized polymer brushes as substrates for the integrin specific adhesion of human umbilical vein endothelial cells

S. Tugulu; P. Silacci; N. Stergiopulos; H-A. Klok 

Biomaterials. 2007. Vol. 28, num. 16, p. 2536 – 2546. DOI : 10.1016/j.biomaterials.2007.02.006.

The thermal polymerization of amino acids revisited; Synthesis and structural characterization of hyperbranched polymers from L-lysine

M. Scholl; T. Nguyen; B. Bruchmann; H-A. Klok 

Journal of Polymer Science Part A: Polymer Chemistry. 2007. Vol. 45, p. 5494 – 5508. DOI : 10.1002/pola.22295.

Thermotropic ionic liquid crystals via self-assembly of cationic hyperbranched polypeptides and anionic surfactants

N. Canilho; M. Scholl; H-A. Klok; R. Mezzenga 

Macromolecules. 2007. Vol. 40, num. 23, p. 8374 – 8383. DOI : 10.1021/ma071558v.

2006

Polymer brushes as ionotropic matrices for the directed fabrication of microstructured calcite thin films

S. Tugulu; M. Harms; M. Fricke; D. Volkmer; H-A. Klok 

Angewandte Chemie – International Edition. 2006. Vol. 45, num. 44, p. 7458 – 7461. DOI : 10.1002/anie.200602382.

Protein function microarrays based on self-immobilizing and self-labeling fusion proteins

I. Sielaff; A. Arnold; G. Godin; S. Tugulu; H-A. Klok et al. 

ChemBioChem. 2006. Vol. 7, num. 1, p. 194 – 202. DOI : 10.1002/cbic.200500278.

Self-assembly of linear polypeptide-based block copolymers

S. Lecommandoux; H-A. Klok; H. Schlaad 

Block Copolymers in Nanoscience; Wiley-VCH Verlag, 2006.

Solid-state structure, organization and properties of peptide-synthetic hybrid block copolymers

H-A. Klok; S. Lecommandoux 

Advances in Polymer Science. 2006. Vol. 202, p. 75 – 111. DOI : 10.1007/12_083.

Thermodynamic confinement and α-helix persistence length in poly(γ-benzyl-L-glutamate)-b-poly(dimethyl siloxane)-b-poly(γ-benzyl-L-glutamate) triblock copolymers

P. Papadopoulos; G. Floudas; I. Schnell; I. Lieberwirth; T. Q. Nguyen et al. 

Biomacromolecules. 2006. Vol. 7, num. 2, p. 618 – 626. DOI : 10.1021/bm050772t.

Water-soluble, unimolecular containers based on amphiphilic multiarm star block copolymers

G. Kreutzer; C. Ternat; T. Q. Nguyen; C. J. G. Plummer; J. A. E. Manson et al. 

Macromolecules. 2006. Vol. 39, num. 13, p. 4507 – 4516. DOI : 10.1021/ma060548b.

Spontaneous condensation in DNA-polystyrene-b-poly(L-lysine) polyelectrolyte block copolymer mixtures

V. Castelletto; I. W. Hamley; S. L. H. Kerstens; S. Deacon; C. D. Thomas et al. 

European Physical Journal E. 2006. Vol. 20, num. 1, p. 1 – 6. DOI : 10.1140/epje/i2005-10074-x.

Synthesis of uniform, non-natural oligomers

N. Franz; G. Kreutzer; H-A. Klok 

Synlett. 2006. num. 12, p. 1793 – 1815. DOI : 10.1055/s-2006-944221.

2005

Biological-synthetic hybrid block copolymers: Combining the best from two worlds

H-A. Klok 

Journal of Polymer Science, Part A: Polymer Chemistry. 2005. Vol. 43, num. 1, p. 1 – 17. DOI : 10.1002/pola.20527.

“Glass transition” in peptides: Temperature and pressure effects

P. Papadopoulos; G. Floudas; I. Schnell; H-A. Klok; T. Aliferis et al. 

Journal of Chemical Physics. 2005. Vol. 122, num. 22, p. 1 – 4. DOI : 10.1063/1.1931657.

Protein-Functionalized Polymer Brushes

S. Tugulu; A. Arnold; I. Sielaff; K. Johnsson; H-A. Klok et al. 

Biomacromolecules. 2005. Vol. 6, num. 3, p. 1602 – 1607. DOI : 10.1021/bm050016n.

Polyphenylene dendrimers as scaffolds for shape-persistent multiple peptide conjugates

G. Mihov; D. Grebel-Koehler; A. Lübbert; G. Vandermeulen; A. Herrmann et al. 

Bioconjugate Chemistry. 2005. Vol. 16, num. 2, p. 283 – 293. DOI : 10.1021/bc049839k.

Solution self-assembly of hybrid block copolymers containing poly(ethylene glycol) and amphiphilic peptide sequences

I. Hamley; I. Ansari; V. Castelletto; H. Nuhn; A. Rösler et al. 

Biomacromolecules. 2005. Vol. 6, num. 3, p. 1310 – 1315. DOI : 10.1021/bm049286g.

Nanostructure formation in poly(γ-benzyl-L-glutamate)-poly(ethylene glycol)-poly(γ-benzyl-L-glutamate) triblock copolymers in the solid state

P. Parras; V. Castelletto; I. W. Hamley; H-A. Klok 

Soft Matter. 2005. Vol. 1, num. 4, p. 284 – 291. DOI : 10.1039/b508772b.

A novel star PEG-derived surface coating for specific cell adhesion

J. Groll; J. Fiedler; E. Engelhard; T. Ameringer; S. Tugulu et al. 

Journal of Biomedical Materials Research – Part A. 2005. Vol. 74, num. 4, p. 607 – 617. DOI : 10.1002/jbm.a.30335.

L-lysine dendronized polystyrene

A. Lübbert; T. Nguyen; H-A. Klok; F. Sun; S. Sheiko 

Macromolecules. 2005. Vol. 38, num. 6, p. 2064 – 2071. DOI : 10.1021/ma047621n.

Peptide mediated formation of hierarchically organized solution and solid state polymer nanostructures

H-A. Klok; H. Nuhn; G. Vandermeulen; A. Rösler; I. Hamley et al. 

Faraday Discussions. 2005. Vol. 128, p. 29 – 41. DOI : 10.1039/b402273d.

PEG-based hybrid block copolymers containing α-helical coiled coil peptide sequences: Control of self-assembly and preliminary biological evaluation

G. Vandermeulen; C. Tziatzios; R. Duncan; H-A. Klok 

Macromolecules. 2005. Vol. 38, num. 3, p. 761 – 769. DOI : 10.1021/ma0485538.

Nonspherical assemblies generated from polystyrene-b-poly(L-lysine) polyelectrolyte block copolymers

A. Lübbert; V. Castelletto; I. W. Hamley; H. Nuhn; M. Scholl et al. 

Langmuir. 2005. Vol. 21, num. 14, p. 6582 – 6589. DOI : 10.1021/la0502600.

Self-assembled nanostructures from peptide-synthetic hybrid block copolymers: Complex, stimuli-responsive rod-coil architectures

J. Babin; J. Rodriguez-Hernandez; S. Lecommandoux; H-A. Klok; M-F. Achard 

Faraday Discussions. 2005. Vol. 128, p. 179 – 192. DOI : 10.1039/b403203a.

2004

Synthesis and Optical Properties of Water-Soluble NIR Absorbing Star Polypeptides based on Functional Rylene Dyes

J. Rodríguez-Hernádez; J. Qu; E. Reuther; H-A. Klok; K. Müllen 

Polymer Bulletin. 2004. Vol. 52, num. 1, p. 57 – 64. DOI : 10.1007/s00289-004-0245-5.

Structure and dynamics of self-assembled poly(ethylene glycol) based coiled-coil nano-objects

G. Vandermeulen; D. Hinderberger; G. Jeschke; H-A. Klok; H. Xu et al. 

ChemPhysChem. 2004. Vol. 5, num. 4, p. 488 – 494. DOI : 10.1002/cphc.200301079.

Synthesis of a silk-inspired peptide-oligothiophene conjugate

H-A. Klok; A. Rösler; G. Götz; E. Mena-Osteritz; P. Bäuerle 

Organic and Biomolecular Chemistry. 2004. Vol. 2, num. 24, p. 3541 – 3544. DOI : 10.1039/b415454a.

Self-assembly and dynamics of poly(γ-benzyl-L-glutamate) peptides

P. Papadopoulos; G. Floudas; H-A. Klok; I. Schnell; T. Pakula 

Biomacromolecules. 2004. Vol. 5, num. 1, p. 81 – 91. DOI : 10.1021/bm034291q.

Peptide/protein hybrid materials: Enhanced control of structure and improved performance through conjugation of biological and synthetic polymers

G. Vandermeulen; H-A. Klok 

Macromolecular Bioscience. 2004. Vol. 4, num. 4, p. 383 – 398. DOI : 10.1002/mabi.200300079.

Chemical approaches for the preparation of biologically-inspired supramolecular architectures and advanced polymeric materials

H-A. Klok 

Highlights in Bioorganic Chemistry: Methods and Applications; Wiley-VCH Verlag, 2004.

Ring-opening polymerization of alpha-amino acid N-carboxyanhydrides

H-A. Klok 

Encyclopledia of Polymer Science and Technology; John Wiley and Sons, 2004.

Metal ion assisted folding and supramolecular organization of a De Novo designed metalloprotein

G. Vandermeulen; C. Tziatzios; D. Schubert; P. Andres; A. Alexeev et al. 

Australian Journal of Chemistry. 2004. Vol. 57, num. 1, p. 33 – 39. DOI : 10.1071/CH03260.

Materials Research Society Symposium Proceedings: Preface

J. Y. Wong; A. L. Plant; C. E. Schmidt; L. Shea; A. J. Coury et al. 

Materials Research Society Symposium Proceedings. 2004. Vol. EXS, num. 1.

2003

Nanoscale structure of poly(ethylene glycol) hybrid block copolymers containing amphiphilic β-strand peptide sequences sequences

A. Rösler; H-A. Klok; I. Hamley; V. Castelletto; O. Mykhaylyk 

Biomacromolecules. 2003. Vol. 4, num. 4, p. 859 – 863. DOI : 10.1021/bm034058s.

Reversible self-organization of poly(ethylene glycol)-based hybrid block copolymers mediated by a de novo four-stranded α-helical coiled coil motif

G. Vandermeulen; H-A. Klok; C. Tziatzios 

Macromolecules. 2003. Vol. 36, num. 11, p. 4107 – 4114. DOI : 10.1021/ma034124i.

Peptide-functionalized polyphenylene dendrimers

A. Herrmann; G. Mihov; G. Vandermeulen; H-A. Klok; K. Müllen 

Tetrahedron. 2003. Vol. 59, num. 22, p. 3925 – 3935. DOI : 10.1016/S0040-4020(03)00461-7.

Small-angle neutron scattering from diblock copolymer poly(styrene-d8)-b-poly(γ-benzyl L-glutamate) solutions: Rod-coil to coil-coil transition

J. Crespo; S. Lecommandoux; R. Borsali; H-A. Klok; J. Crespo et al. 

Macromolecules. 2003. Vol. 36, num. 4, p. 1253 – 1256. DOI : 10.1021/ma021176j.

From supramolecular polymersomes to stimuli-responsive nano-capsules based on poly(diene-b-peptide) diblock copolymers

F. Chécot; S. Lecommandoux; Y. Gnanou; H-A. Klok 

European Physical Journal E. 2003. Vol. 10, num. 1, p. 25 – 35. DOI : 10.1140/epje/e2003-00006-1.

Synthesis and Self-Organization of Rod-Dendron and Dendron-Rod-Dendron Molecules

S. Lecommandoux; H-A. Klok; M. Sayar; S. Stupp; S. Lecommandoux 

Journal of Polymer Science, Part A: Polymer Chemistry. 2003. Vol. 41, num. 22, p. 3501 – 3518. DOI : 10.1002/pola.10855.

Highly branched poly(L-lysine)

J. Rodríguez-Hernández; M. Gatti; H-A. Klok 

Biomacromolecules. 2003. Vol. 4, num. 2, p. 249 – 258. DOI : 10.1021/bm020096k.