Chemoselective Pd-Based Dyotropic Rearrangement: Fluorocyclization and Regioselective Wacker Reaction of Homoallylic Amides

C. Liu; Q. Wang; J. Zhu 

[4+1] Heteroannulation to Form 1‐Pyrrolines through Alder‐Ene Reaction of in situ Generated Ynimines: Development and Application in Total Synthesis of Borrecapine

R. Lavernhe; Q. Wang; J. Zhu 

Quaternary Carbon Editing Enabled by Sequential Palladium Migration

H. Wu; T. Fujii; Q. Wang; J. Zhu 

Inherently chiral nor-heteracalixarenes: design and synthesis via enantioselective intramolecular Suzuki-Miyaura reaction

Y-F. Jiang; S. Tong; J. Zhu; M-X. Wang 

Arylative Ring Expansion of 3-Vinylazetidin-3-Ols and 3-Vinyloxetan-3-Ols to Dihydrofurans by Dual Palladium and Acid Catalysis

T. Fujii; Q. Wang; J. Zhu 

Benzylic C(sp3)-H Azidation: Copper vs Iron Catalysis

A. Renteria-Gomez; R. O. Torres-Ochoa; P. Palamini; R. Simonet-Davin; Q. Wang et al. 

Chalcogen bonding catalysis

G. Sekar; V. V. Nair; J. Zhu 

Editing Tetrasubstituted Carbon: Dual C–O Bond Functionalization of Tertiary Alcohols Enabled by Palladium-Based Dyotropic Rearrangement

T. C. P. Delcaillau; B. Yang; Q. Wang; J. Zhu 

Palladium‐Based Dyotropic Rearrangement Enables A Triple Functionalization of Gem‐Disubstituted Alkenes: An Unusual Fluorolactonization Reaction

Q. Feng; C. Liu; Q. Wang; J. Zhu 

Design and Synthesis of C4‐Symmetric Axially Chiral β‐Aryl Porphyrins and Application for Supporting Ir(III)‐Catalyzed Enantioselective C−H Alkylation

S. Yuan; J. Sun; X. Zhao; J. Zhu; S. Zheng 

Catalytic Enantioselective Synthesis of Inherently Chiral Macrocycles by Dynamic Kinetic Resolution

Q-L. Lu; X-D. Wang; S. Tong; J. Zhu; M-X. Wang 

Investigation of palladium(IV) species in organic synthesis and synthetic studies towards meloyunnanine A

Access to lignan families from biomass-derived starting material

Asymmetric Construction of α,α‐Disubstituted Piperazinones Enabled by Benzilic Amide Rearrangement

Y. He; R. Quan; X. Li; J. Zhu; H. Wu 

Terminal Alkynes as One-Carbon Donors in [5+1] Heteroannulation: Synthesis of Pyridines via Ynimine Intermediates and Application in the Total Synthesis of Anibamine B

R. Lavernhe; Q. Wang; J. Zhu 

Divergent Asymmetric Total Synthesis of (−)‐Voacafricines A and B

R. Andres; Q. Wang; J. Zhu 

Highly Strained Oxygen‐Doped Chiral Molecular Belts of the Zigzag‐Type with Strong Circularly Polarized Luminescence

J. Chen; Z. Jiang; H. Xiao; S. Tong; T. Shi et al. 

Oxidative rearrangement of 1,1-disubstituted alkenes to ketones

Q. Feng; Q. Wang; J. Zhu 

Enantioselective Total Synthesis of (+)-Stephadiamine

B. Yang; G. Li; Q. Wang; J. Zhu 

Inherently chiral calixarenes by a catalytic enantioselective desymmetrizing cross-dehydrogenative coupling

X. Zhang; S. Tong; J. Zhu; M-X. Wang 

Organocatalytic Enantioselective Pictet–Spengler Reaction of α‐Ketoesters: Development and Application to the Total Synthesis of (+)‐Alstratine A

R. Andres; F. Sun; Q. Wang; J. Zhu 

Synthesis and Applications of Ynimines and Enantioselective Total Synthesis of Artatrovirenol A

Diverting the 5-exo-Trig Oxypalladation to Formally 6-endo-Trig Fluorocycloetherification Product through 1,2-O/Pd(IV) Dyotropic Rearrangement

J. Gong; Q. Wang; J. Zhu 

Asymmetric Synthesis of Enantioenriched Zigzag-Type Molecular Belts by Kinetic Resolution and Subsequent Transformations

Y-Q. Mao; Y. Zhang; S. Tong; J. Zhu; M-X. Wang 

TiCl3-Mediated Reductive Cyclization of Tetrasubstituted Alkenes and Enol Esters Bearing a 2-Nitrophenyl Substituent

Dual Photoredox and Copper Catalysis: Enantioselective 1,2-Amidocyanation of 1,3-Dienes

D. Forster; W. Guo; Q. Wang; J. Zhu 

Organocatalytic Enantioselective Diels-Alder Reaction of 2-Trifluoroacetamido-1,3-dienes with alpha,beta-Unsaturated Ketones

X-Q. Zhu; Q. Wang; J. Zhu 

Apparent 6-endo-trig Carbofluorination of Alkenes Enabled by Palladium-Based Dyotropic Rearrangement

J. Gong; Q. Wang; J. Zhu 

Synthesis of 3-Acyloxyindolenines by TiCl3-Mediated Reductive Cyclization of 2-(ortho-Nitroaryl)-Substituted Enol Esters

D. V. Boyarskaya; A. Ongaro; C. Piemontesi; Q. Wang; J. Zhu 

Migrative Carbofluorination of Saturated Amides Enabled by Pd-Based Dyotropic Rearrangement

G. Yang; H. Wu; S. Gallarati; C. Corminboeuf; Q. Wang et al. 

Wind-tunnel experimental studies of the spatial snow distribution over grass and bush surfaces

G. Li; J-m. Qin; H-x. Yu; N. Huang 

Two-Carbon Ring Expansion of Cyclobutanols to Cyclohexenones Enabled by Indole Radical Cation Intermediate: Development and Application to a Total Synthesis of Uleine

A. Leclair; Q. Wang; J. Zhu 

Asymmetric Total Synthesis of Indole Alkaloids (+)-Condyfoline, (-)-Tubifoline, (+)-Dasycarpidone and (+)-Uleine

Application of superstatistical analysis on fluctuant surface shear in particle-laden turbulence boundary layer

G. Li; W. He; B. Yang; H. Yu; N. Huang et al. 

Catalytic Enantioselective Pictet–Spengler Reaction of α‐Ketoamides Catalyzed by a Single H‐Bond Donor Organocatalyst

R. Andres; Q. Wang; J. Zhu 

Taming the radical cation intermediate enabled one-step access to structurally diverse lignans

J-C. Xiang; C. Fung; Q. Wang; J. Zhu 

Catalytic enantioselective Pictet-Spengler reaction of carbonyl compounds: Development and application to the asymmetric total synthesis of indole alkaloids

Photoredox Catalytic Three-Component Amidoazidation of 1,3-Dienes

D. Forster; W. Guo; Q. Wang; J. Zhu 

Copper‐Catalyzed Aza‐Sonogashira Cross‐Coupling to Ynimines: Development and Application to the Synthesis of Heterocycles

R. Lavernhe; R. O. Torres-Ochoa; Q. Wang; J. Zhu 

Enantioselective Total Synthesis of (+)-Nordasycarpidone, (+)-Dasycarpidone, and (+)-Uleine

B. Delayre; C. Fung; Q. Wang; J. Zhu 

C-C bond activation enabled by dyotropic rearrangement of Pd(iv) species

J. Cao; H. Wu; Q. Wang; J. Zhu 

Visible light photoredox-catalysed remote C-H functionalisation enabled by 1,5-hydrogen atom transfer (1,5-HAT)

W. Guo; Q. Wang; J. Zhu 

Enantioselective Total Synthesis of (+)-Alstilobanine C, (+)-Undulifoline, and (-)-Alpneumine H

G. Li; N. Gaeng; C. Piemontesi; Q. Wang; J. Zhu 

Selective 1,2-Aminoisothiocyanation of 1,3-Dienes Under Visible-Light Photoredox Catalysis

W. Guo; Q. Wang; J. Zhu 

Catalytic Enantioselective Synthesis of Morpholinones Enabled by Aza-Benzilic Ester Rearrangement

Y-P. He; H. Wu; Q. Wang; J. Zhu 

Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids

G. Li; Q. Wang; J. Zhu 

Development of remote C-H bond functionalization of redox-active alcohol derivatives and oxidative transformations under photoredox catalysis

Catalytic Enantioselective Aminopalladation–Heck Cascade

Y. He; J. Cao; H. Wu; Q. Wang; J. Zhu 

Iron-Catalysed Remote C(sp3)-H Azidation of O-Acyl Oximes and N -Acyloxy Imidates

A. Leclair; R. O. Torres-Ochoa; Q. Wang; J. Zhu 

Natural Product Synthesis Enabled by Domino Processes Incorporating a 1,2-Rearrangement Step

B. Delayre; Q. Wang; J. Zhu 

Macrocyclization of omega-Isocyanoaldehydes and Towards the Total Synthesis of Jamaicensamide A

Conceptual design of 1000 m scale steel-UHPFRC composite truss arch bridge

X. Shao; G. He; X. Shen; P. Zhu; Y. Chen 

Radical-Cation Cascade to Aryltetralin Cyclic Ether Lignans Under Visible-Light Photoredox Catalysis

J-C. Xiang; Q. Wang; J. Zhu 

Palladium-Catalyzed Multicomponent Synthesis of Fully Substituted Alkylidene Furanones

A. Renteria-Gomez; R. O. Torres-Ochoa; R. Gamez-Montano; Q. Wang; J. Zhu 

Asymmetric Total Synthesis of (-)-Arborisidine and (-)-19-epi-Arborisidine Enabled by a Catalytic Enantioselective Pictet-Spengler Reaction

R. Andres; Q. Wang; J. Zhu 

Synthesis of Benzo[a]carbazoles through Visible Light-Induced Cycloaromatization

B. Yao; Q. Wang; J. Zhu 

TiCl3-Mediated Synthesis of 2,3,3-Trisubstituted Indolenines: Total Synthesis of (+)-1,2-Dehydroaspidospermidine, (+)-Condyfoline, and (-)-Tubifoline

B. Delayre; C. Piemontesi; Q. Wang; J. Zhu 

Copper-Catalyzed Cyanoalkylative Aziridination of N-Sulfonyl Allylamines

T. M. Ha; W. Guo; Q. Wang; J. Zhu 

Catalytic Enantioselective Benzilic Ester Rearrangement

H. Wu; Q. Wang; J. Zhu 

Towards the Sarpagine-Ajmaline-Macroline Family of Indole Alkaloids: Enantioselective Synthesis of an N-Demethyl Alstolactone Diastereomer

D. Dagoneau; Q. Wang; J. Zhu 

Fused N‐Heterocycles with Contiguous Stereogenic Centers Accessed by an Asymmetric Catalytic Cascade Reaction of Tertiary Enamides

L. Zhen; S. Tong; J. Zhu; M. Wang 

Palladium-Catalyzed Enantioselective Cacchi Reaction: Asymmetric Synthesis of Axially Chiral 2,3-Disubstituted Indoles

Y-P. He; H. Wu; Q. Wang; J. Zhu 

Catalytic Enantioselective Synthesis and Switchable Chiroptical Property of Inherently Chiral Macrocycles

S. Tong; J-T. Li; D-D. Liang; Y-Zhang; Q-Y. Feng et al. 

Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes

Z. Li; R. O. Torres-Ochoa; Q. Wang; J. Zhu 

Copper-Catalyzed 1,2-Methoxy Methoxycarbonylation of Alkenes with Methyl Formate and Synthetic Studies Towards the Total Synthesis of Koumine, Voacafricine A and Voacafricine B

Construction of the Erythrinane Core Skeleton via Asymmetric Catalytic Cascade Reaction of Tertiary Enamides

L. Zhen; S. Tong; J. Zhu; M-X. Wang 

Organocatalytic Double Ugi Reaction with Statistical Amplification of Product Enantiopurity: A Linker Cleavage Approach To Access Highly Enantiopure Ugi Products

Q-Y. Feng; J. Zhu; M-X. Wang; S. Tong 

Desymmetrization of Prochiral Cyclopentenes Enabled by Enantioselective Palladium-Catalyzed Oxidative Heck Reaction

G. Chen; J. Cao; Q. Wang; J. Zhu 

Multifunctional hybrid alginate-based hydrogels for cell immobilization

Remote C(sp(3))-H Arylation and Vinylation of N-Alkoxypyridinium Salts to delta-Aryl and delta-Vinyl Alcohols

X. Bao; Q. Wang; J. Zhu 

Investigating cortactin as a genetic driver of disease progression in invasive lobular carcinoma

N. Tasdemir; M. J. Sikora; L. Zhu; K. M. Levine; J. Scott et al. 

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

S-C. Zheng; Q. Wang; J. Zhu 

Copper-Catalyzed 1,2-Methoxy Methoxycarbonylation of Alkenes with Methyl Formate

B. Budai; A. Leclair; Q. Wang; J. Zhu 

Dual Photoredox/Copper Catalysis for the Remote C(sp3 )−H Functionalization of Alcohols and Alkyl Halides by N -Alkoxypyridinium Salts

X. Bao; Q. Wang; J. Zhu 

Iron‐Catalysed Remote C(sp 3 )−H Azidation of O ‐Acyl Oximes and N ‐Acyloxy Imidates Enabled by 1,5‐Hydrogen Atom Transfer of Iminyl and Imidate Radicals: Synthesis of γ‐Azido Ketones and β‐Azido Alcohols

R. O. Torres‐Ochoa; A. Leclair; Q. Wang; J. Zhu 

Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement

G. Li; C. Piemontesi; Q. Wang; J. Zhu 

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

S-C. Zheng; Q. Wang; J. Zhu 

Intramolecular Arylation of Tertiary Enamides through Pd(OAc)2-Catalyzed Dehydrogenative Cross-Coupling Reaction: Construction of Fused N-Heterocyclic Scaffolds and Synthesis of Isoindolobenzazepine Alkaloids

W. Zhu; S. Tong; J. Zhu; M-X. Wang 

Palladium-Catalyzed Synthesis of Ketenimines from Isocyanides and Synthetic Studies Towards the Total Synthesis of Mersilongine

Catalytic Enantioselective Pinacol and Meinwald Rearrangements for the Construction of Quaternary Stereocenters

H. Wu; Q. Wang; J. Zhu 

Construction of Quaternary Stereocenters by Palladium-Catalyzed Carbopalladation-Initiated Cascade Reactions

Y. Ping; Y. Li; J. Zhu; W. Kong 

Copper-catalyzed remote C(sp3)–H azidation and oxidative trifluoromethylation of benzohydrazides

X. Bao; Q. Wang; J. Zhu 

Catalytic Enantioselective α-Ketol Rearrangement

H. Wu; R. Andres; Q. Wang; J. Zhu 

Recent Advances in Catalytic Enantioselective Rearrangement

H. Wu; Q. Wang; J. Zhu 

Formal [4+1] Cycloaddition of o ‐Aminobenzyl Chlorides with Isocyanides: Synthesis of 2‐Amino‐3‐Substituted Indoles

J. A. W. Jong; X. Bao; Q. Wang; J. Zhu 

Total Synthesis of Alstolactine A & Synthetic Studies Towards Members of Akuammiline Alkaloids

From isonitrile to nitrile via ketenimine intermediate: Palladium-catalyzed 1,1-carbocyanation of ally carbonate by alpha-isocyanoacetate

G. Qiu; C. Sornay; D. Savary; S-C. Zheng; Q. Wang et al. 

Lewis acid catalyst-steered divergent synthesis of functionalized vicinal amino alcohols and pyrroles from tertiary enamides

X-M. Xu; C-H. Lei; S. Tong; J. Zhu; M-X. Wang 

Enantioselective total synthesis of (+)-Peganumine A

C. Piemontesi; Q. Wang; J. Zhu 

Development of functionalized alginate-based hydrogels to reduce fibrosis in the transplantation of microencapsulated cells

Cooperative Pd/Cu Catalysis: Multicomponent Synthesis of Tetrasubstituted Imidazolones from Methyl α-Isocyanoacetates, Primary Amines, and Aryl(vinyl) Iodides

A. Clemenceau; Q. Wang; J. Zhu 

Metamorphosis of cycloalkenes for the divergent total synthesis of polycyclic indole alkaloids

Z. Xu; Q. Wang; J. Zhu 

Copper-Catalyzed Arylation of Remote C(sp3 )−H Bonds in Carboxamides and Sulfonamides

Z. Li; Q. Wang; J. Zhu 

Copper-Catalyzed Enantioselective Arylative Desymmetrization of Prochiral Cyclopentenes with Diaryliodonium Salts

H. Wu; Q. Wang; J. Zhu 

Still Unconquered: Enantioselective Passerini and Ugi Multicomponent Reactions

Q. Wang; D-X. Wang; M-X. Wang; J. Zhu 

Indole Alkaloids, Macrocycles and Heterocycles : Interplay between Methodological Development and Total Synthesis

Total Synthesis of Alstilobanine C, Undulifoline and Alstilobanine B

Copper-catalyzed methylative difunctionalization of alkenes

X. Bao; T. Yokoe; T. M. Ha; Q. Wang; J. Zhu 

Palladium-Catalyzed Enantioselective Desymmetrizing Aza-Wacker Reaction: Development and Application to the Total Synthesis of (−)-Mesembrane and (+)-Crinane

X. Bao; Q. Wang; J. Zhu 

Heteroannulation of Arynes with α-Amino Imides: Synthesis of 2,2-Disubstituted Indolin-3-ones and Application to the Enantioselective Total Synthesis of (+)-Hinckdentine A

R. O. Torres-Ochoa; T. Buyck; Q. Wang; J. Zhu 

Chiral phosphoric acid-catalyzed enantioselective three-component Mannich reaction of acyclic ketones, aldehydes and anilines

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Hydrogels based on functionalized polysaccharides

S. Gerber; S. Passemard; C. Wandrey; L. Buhler; P. Morel 

Water as a Hydride Source in Palladium-Catalyzed Enantioselective Reductive Heck Reactions

W. Kong; Q. Wang; J. Zhu 

Palladium-Catalyzed Three-Component Reaction of Propargyl Carbonates, Isocyanides, and Alcohols or Water: Switchable Synthesis of Pyrroles and Its Bicyclic Analogues

G. Qiu; Q. Wang; J. Zhu 

Copper-Catalyzed Enantioselective Domino Arylation/Semipinacol Rearrangement of Allylic Alcohols with Diaryliodonium Salts

H. Wu; Q. Wang; J. Zhu 

“Palladium-Catalyzed Diamination of Alkynes in Synthesis of Tetracycles” and “Copper-Catalyzed Cyanoalkylation of Unactivated Alkenes”

Organocatalytic Nucleophilic Addition of Hydrazones to Imines: Synthesis of Enantioenriched Vicinal Diamines

Y. Wang; Q. Wang; J. Zhu 

Palladium-Catalyzed Enantioselective Narasaka-Heck Reaction/Direct C−H Alkylation of Arenes: Iminoarylation of Alkenes

X. Bao; Q. Wang; J. Zhu 

“Divergent Total Synthesis of (-)-Rhazinilam, (-)-Leucomidine B and (+)-Leuconodine F” and “Synthetic Studies Towards Sarpagine-Related Indoles”

To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis

M. Giustiniano; A. Basso; V. Mercalli; A. Massarotti; E. Novellino et al. 

Silver-Catalyzed Three-Component 1,1-Aminoacylation of Homopropargylamines: α-Additions for Both Terminal Alkynes and Isocyanides

S. Tong; C. Piemontesi; Q. Wang; M-X. Wang; J. Zhu 

α-Oxo-Ketenimines from Isocyanides and α-Haloketones: Synthesis and Divergent Reactivity

M. Mamboury; Q. Wang; J. Zhu 

Catalytic Enantioselective Double Carbopalladation/C−H Functionalization with Statistical Amplification of Product Enantiopurity: A Convertible Linker Approach

S. Tong; A. Limouni; Q. Wang; M-X. Wang; J. Zhu 

Around isocyanide reactivity : development of enantioselective transformations and syntheses of heterocycles and natural products

Fluorophores for Excited-State Intramolecular Proton Transfer by an Yttrium Triflate Catalyzed Reaction of Isocyanides with Thiocarboxylic Acids

S. Tong; S. Zhao; Q. He; Q. Wang; M-X. Wang et al. 

Copper-Catalyzed Three-Component Carboazidation of Alkenes with Acetonitrile and Sodium Azide

A. Bunescu; T. M. Ha; Q. Wang; J. Zhu 

Silver Nitrate-Catalyzed Isocyanide Insertion/Lactamization Sequence to Imidazolones and Quinazolin-4-ones: Development and Application in Natural Product Synthesis

A. Clemenceau; Q. Wang; J. Zhu 

Organocatalytic Enantioselective Acyloin Rearrangement of α-Hydroxy Acetals to α-Alkoxy Ketones

H. Wu; Q. Wang; J. Zhu 

Microencapsulation of hepatocytes and mesenchymal stem cells for therapeutic applications

Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-Cadherin interaction and prolong function of transplanted encapsulated islets in mice

E. Montanari; R. P. H. Meier; R. Mahou; J. D. Seebach; C. Wandrey et al. 

Multi-harmonic imaging in the second near-infrared window of nanoparticle-labeled stem cells as effective monitoring tool in tissue depth

L. Dubreil; I. Leroux; M. Ledevin; C. Schleder; L. Lagalice et al. 

Synthesis strategies to extend the variety of alginate-based hybrid hydrogels for cell microencapsulation

S. Passemard; L. Szabó; F. R. P. Noverraz; E. Montanari; C. Gonelle-Gispert et al. 

The Swiss Summer School in Chemical Biology 2016 in brief

J. Saarbach; R. De Matos; P. Gonschorek 

Enantioselective Synthesis of Quaternary α-Amino Acids Enabled by the Versatility of the Phenylselenonyl Group

A. Clemenceau; Q. Wang; J. Zhu 

Copper-catalysed cyanoalkylative cycloetherification of alkenes to 1,3-dihydroisobenzofurans: development and application to the synthesis of citalopram

T. M. Ha; Q. Wang; J. Zhu 

Enantioselective Total Syntheses of (−)-Rhazinilam, (−)-Leucomidine B, and (+)-Leuconodine F

D. Dagoneau; Z. Xu; Q. Wang; J. Zhu 

Synthesis of Vinyl Isocyanides and Development of a Convertible Isonitrile

M. Spallarossa; Q. Wang; R. Riva; J. Zhu 

Enantioselective Synthesis of (+)-Peganumine A

C. Piemontesi; Q. Wang; J. Zhu 

Organocatalytic Enantioselective Vinylogous Pinacol Rearrangement Enabled by Chiral Ion Pairing

H. Wu; Q. Wang; J. Zhu 

Chiral Phosphoric Acid-Catalyzed Enantioselective Formal [3+2] Cycloaddition of Azomethine Imines with Enecarbamates

Y. Wang; Q. Wang; J. Zhu 

Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct

Y. Zhang; Y-F. Ao; Z-T. Huang; D-X. Wang; M-X. Wang et al. 

Copper-Catalyzed Formal [2+2+1] Heteroannulation of Alkenes, Alkylnitriles, and Water: Method Development and Application to a Total Synthesis of (±)-Sacidumlignan D

T. M. Ha; C. Chatalova-Sazepin; Q. Wang; J. Zhu 

Synthesis of Diversely Functionalized Oxindoles Enabled by Migratory Insertion of Isocyanide to a Transient σ-Alkylpalladium(II) Complex

W. Kong; Q. Wang; J. Zhu 

Enantioselective Total Synthesis of (−)-Terengganensine A

C. Piemontesi; Q. Wang; J. Zhu 

Catalytic Asymmetric Tandem Reaction of Tertiary Enamides: Expeditious Synthesis of Pyrrolo[2,1-a]isoquinoline Alkaloid Derivatives

X-M. Xu; L. Zhao; J. Zhu; M-X. Wang 

Switchable [3+2] and [4+2] Heteroannulation of Primary Propargylamines with Isonitriles to Imidazoles and 1,6-Dihydropyrimidines: Catalyst Loading Enabled Reaction Divergence

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Synthesis of Oxazolidin-2-ones by Oxidative Coupling of Isonitriles, Phenyl Vinyl Selenone, and Water

T. Buyck; D. Pasche; Q. Wang; J. Zhu 

Ketenimines from Isocyanides and Allyl Carbonates: Palladium-Catalyzed Synthesis of β,γ-Unsaturated Amides and Tetrazoles

G. Qiu; M. Mamboury; Q. Wang; J. Zhu 

Total Synthesis of (±)-Strictamine

W. Ren; Q. Wang; J. Zhu 

Pancreatic islet cells isolation and transplantation into the bone marrow

R. P. H. Meier; P. Sun; S. Gerber-Lemaire; T. Berney; Y. D. Muller 

Contribution of polymeric materials to progress in xenotransplantation of microencapsulated cells – A review

R. Mahou; S. Passemard; M. Carvello; A. Petrelli; F. Noverraz et al. 

Laureates: Junior Prizes of the SCS Fall Meeting 2015

S. Gerber 

Hydrogels based on functionalized polysaccharides

S. Gerber; S. Passemard; C. Wandrey; L. H. Bühler; P. Morel 

Copper-Catalyzed Cyanomethylation of Allylic Alcohols with Concomitant 1,2-Aryl Migration: Efficient Synthesis of Functionalized Ketones Containing an α-Quaternary Center

A. Bunescu; Q. Wang; J. Zhu 

Pd/C-Catalyzed Cyclizative Cross-Coupling of Two ortho-Alkynylanilines under Aerobic Conditions: Synthesis of 2,3’-Bisindoles

B. Yao; Q. Wang; J. Zhu 

Total Synthesis of Aspidosperma Family Indole Alkaloids through the iORC Domino Process

Integrated One-Pot Synthesis of 1,3-Oxazinan-2-ones from Isocyanoacetates and Phenyl Vinyl Selenones

T. Buyck; Q. Wang; J. Zhu 

Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

D. Staedler; S. M. F. M. Passemard; T. Magouroux; A. Rogov; C. M. Maguire et al. 

Human Mesenchymal Stromal Cells Improve Survival And Function Of Pancreatic Islets By Cell-To-Cell Contact

E. Montanari; R. Mahou; S. Passemard; F. Noyerraz; P. Morel et al. 

Copper-Catalyzed Intermolecular Carboetherification of Unactivated Alkenes by Alkyl Nitriles and Alcohols

C. Chatalova-Sazepin; Q. Wang; G. M. Sammis; J. Zhu 

Palladium-Catalyzed Enantioselective Domino Heck/Intermolecular C–H Bond Functionalization: Development and Application to the Synthesis of (+)-Esermethole

W. Kong; Q. Wang; J. Zhu 

Sulfonamide and Tertiary Amine as Nucleophiles in Pd(II)-Catalyzed Diamination of Alkynes: Synthesis of Tetracyclic Indolobenzothiazine S,S‑Dioxides

T. M. Ha; B. Yao; Q. Wang; J. Zhu 

Tuning the Reactivity of Isocyano Group: Synthesis of Imidazoles and Imidazoliums from Propargylamines and Isonitriles in the Presence of Multiple Catalysts

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Synthesis of diverse di- to penta-substituted 1,2-dihydropyridine derivatives from gold(I)-catalyzed intramolecular addition of tertiary enamides to alkynes

X. Zhang; X-M. Xu; L. Zhao; J. You; J. Zhu et al. 

2-(Methoxycarbonyl)ethyl as a Removable N-Protecting Group: Synthesis of Indoloisoquinolinones by Pd(II)-Catalyzed Intramolecular Diamination of Alkynes

T. M. Ha; B. Yao; Q. Wang; J. Zhu 

Enantioselective Synthesis of Putative Lipiarmycin Aglycon Related to Fidaxomicin/Tiacumicin B

W. Erb; J-M. Grassot; D. Linder; L. Neuville; J. Zhu 

Total Syntheses of (−)-Mersicarpine, (−)-Scholarisine G, (+)-Melodinine E, (−)-Leuconoxine, (−)-Leuconolam, (−)-Leuconodine A, (+)-Leuconodine F, and (−)-Leuconodine C: Self-Induced Diastereomeric Anisochronism (SIDA) Phenomenon for Scholarisine G and Leuconodines A and C

Z. Xu; Q. Wang; J. Zhu 

Chiral Calcium–BINOL Phosphate Catalyzed Diastereo- and Enantioselective Synthesis of syn-1,2-Disubstituted 1,2-Diamines: Scope and Mechanistic Studies

C. Lalli; A. Dumoulin; C. Lebée; F. Drouet; V. Guérineau et al. 

Aqueous Titanium Trichloride Promoted Reductive Cyclization of o-Nitrostyrenes to Indoles: Development and Application to the Synthesis of Rizatriptan and Aspidospermidine

S. Tong; Z. Xu; M. Mamboury; Q. Wang; J. Zhu 

Multicomponent Reactions in Organic Synthesis

Pd-Catalyzed Dehydrogenative Aryl−Aryl Bond Formation via Double C(sp2)−H Bond Activation: Efficient Synthesis of [3,4]-Fused Oxindoles

A. Bunescu; T. Piou; Q. Wang; J. Zhu 

An Enantioselective Total Synthesis of (−)-Isoschizogamine

Z. Xu; X. Bao; Q. Wang; J. Zhu 

Synthesis of Functionalized Epoxides by Copper-Catalyzed Alkylative Epoxidation of Allylic Alcohols with Alkyl Nitriles

A. Bunescu; Q. Wang; J. Zhu 

Tuning the Properties of Hydrogel Microspheres by Adding Chemical Cross-linking Functionality to Sodium Alginate

R. Mahou; F. Borcard; V. Crivelli; E. Montanari; S. Passemard et al. 

Functionalized bismuth ferrite harmonic nanoparticles for cancer cells labelling and imaging

S. M. F. M. Passemard; D. Staedler; G. Sonego; T. Magouroux; G. S. Schneiter et al. 

Simultaneous Multi-Harmonic Imaging of Nanoparticles in Tissues for Increased Selectivity

A. Rogov; M. Irondelle; F. Ramos-Gomez; J. Bode; D. Staedler et al. 

Three-Component Povarov Reaction–Heteroannulation with Arynes: Synthesis of 5,6-Dihydroindolo[1,2‑a]quinolines

A. Bunescu; Q. Wang; J. Zhu 

Copper-catalyzed three-component synthesis of 5-acetamidoimidazoles from carbodiimides, acyl chlorides and isocyanides

G. Sapuppo; Q. Wang; D. Swinnen; J. Zhu 

Chiral Phosphoric Acid-Catalyzed Enantioselective Three- Component Aza-Diels-Alder Reactions of Aminopyrroles and Aminopyrazoles

J. Brioche; T. Courant; L. Alcaraz; M. Stocks; M. Furber et al. 

Total Synthesis of (±)-Aspidophylline A

W. Ren; Q. Wang; J. Zhu 

Phosphoric Acid Catalyzed Desymmetrization of Bicyclic Bislactones Bearing an All-Carbon Stereogenic Center: Total Syntheses of (−)-Rhazinilam and (−)-Leucomidine B

J-B. Gualtierotti; D. Pasche; Q. Wang; J. Zhu 

NIS-Assisted Aza-Friedel-Crafts Reaction with α-Carbamoysulfides as Precursors of

N. George; M. Bekkaye; A. Alix; J. Zhu; G. Masson 

From Racemic to Enantioselective Total Synthesis of Trigonoliimines via Development of an Organocatalytic Enantioselective Michael Addition of α-Aryl-α-isocyanoacetate to Vinyl Phenyl Selenone

T. Buyck; Q. Wang; J. Zhu 

Phosphoric Acid Catalyzed Diastereo- and Enantioselective Synthesis of Substituted 1,3-Diaminotetralins

G. Dagousset; W. Erb; J. Zhu; G. Masson 

Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples

D. Staedler; T. Magouroux; S. Passemard; S. Schwung; M. Dubled et al. 

Plastidic type I signal peptidase 1 is a redox-dependent thylakoidal processing peptidase

T. Midorikawa; J. K. Endow; J. Dufour; J. Zhu; K. Inoue 

Triple Role of Phenylselenonyl Group Enabled a One-Pot Synthesis of 1,3-Oxazinan-2-ones From α-Isocyanoacetates, Phenyl Vinyl Selenones, and Water

T. Buyck; Q. Wang; J. Zhu 

On the Formation and Transformation of alpha-Iminonitriles, the Desymmetrization of Bicyclic Bislactones and Total Synthesis of (-)-Leucomidine B and (-)-Rhazinilam

Isocyanoacetates as Synthetic Platform Towards Natural Products and Biologically Relevant Scaffolds

Mechanistic Study on the Palladium(II)-Catalyzed Synthesis of 2,3-Disubstituted Indoles Under Aerobic Conditions: Anion Effects and the Development of a Low-Catalyst-Loading Process

B. Yao; Q. Wang; J. Zhu 

Functionalized imidazoliniums from the three-component domino reaction of N-formylmethylcarboxamides with amines and isocyanides

C-H. Lei; L. Zhao; D-X. Wang; J. Zhu; M-X. Wang 

“New methods for indoles and [3,4]-fused oxindoles syntheses” and “Copper-catalyzed/mediated difunctionalization of alkenes with alkylnitriles”

Multicomponent Domino Process: Rational Design and Serendipity

Copper-Mediated/Catalyzed Oxyalkylation of Alkenes with Alkylnitriles

A. Bunescu; Q. Wang; J. Zhu 

Unified Strategy to Monoterpene Indole Alkaloids: Total Syntheses of (±)-Goniomitine, (±)-1,2-Dehydroaspidospermidine, (±)-Aspidospermidine, (±)-Vincadifformine, and (±)-Kopsihainanine A

O. Wagnières; Z. Xu; Q. Wang; J. Zhu 

New models and techniques to simulate realistic biological membranes

Functionalization of Nanoparticles for Targeted Cancer Imaging and Diagnosis

Development and evaluation of new nanoprobes for cancer cell targeting and imaging

Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR

R. Buratto; A. Bornet; J. Milani; D. Mammoli; B. Vuichoud et al. 

Compounds for functionalizing biomaterials

S. Gerber; F. Borcard; L. Juillerat; U. Gonzenbach; F. Krauss Juillerat 

Nonlinear optical and magnetic properties of BiFeO3 harmonic nanoparticles

S. Schwung; A. Rogov; G. Clarke; C. Joulaud; T. Magouroux et al. 

Enzyme and Acid Deconjugation of Plasma Sulfated Metanephrines

M. Glauser; M. Metrailler; S. Gerber-Lemaire; C. Centeno; C. Seghezzi et al. 

Palladium-Catalyzed Through-Space C(sp3)-H and C(sp2)-H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]- Fused Oxindoles

T. Piou; A. Bunescu; Q. Wang; L. Neuville; J. Zhu 

Pd(II)-catalyzed intramolecular aminopalladation/direct C–H arylation under aerobic conditions: synthesis of pyrrolo[1,2-a]indoles

T. Piou; L. Neuville; J. Zhu 

Catalytic Enantioselective Michael Addition of α-Aryl-α-Isocyanoacetates to Vinyl Selenone: Synthesis of α,α-Disubstituted α-Amino Acids and (+)- and (−)-Trigonoliimine A

T. Buyck; Q. Wang; J. Zhu 

Synthetic Study towards Strictamine: The Oxidative Coupling Approach

W. Ren; N. Tappin; Q. Wang; J. Zhu 

Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

J. Zhu 

Synthesis of 3,3-disubstituted oxindoles by one-pot integrated Brønsted base-catalyzed trichloroacetimidation of 3-hydroxyoxindoles and Brønsted acid-catalyzed nucleophilic substitution reaction

C. Piemontesi; Q. Wang; J. Zhu 

Heteroannulation of arynes with N-aryl-α-aminoketones for the synthesis of unsymmetrical N-aryl-2,3-disubstituted indoles: an aryne twist of Bischler–Möhlau indole synthesis

A. Bunescu; C. Piemontesi; Q. Wang; J. Zhu 

Synthesis of Substituted Pyridines from Cascade [1 + 5] Cycloaddition of Isonitriles to

C-H. Lei; D-X. Wang; L. Zhao; J. Zhu; M-X. Wang 

Synthesis of Multifunctionalized 1,2,3,4-Tetrahydropyridines, 2,3-Dihydropyridin-4(1H)-ones, and Pyridines from Tandem Reactions Initiated by [5+1] Cycloaddition of N-Formylmethyl-Substituted Enamides to Isocyanides: Mechanistic Insight and Synthetic Application

C-H. Lei; D-X. Wang; L. Zhao; J. Zhu; M-X. Wang 

Zinc Bromide Promoted Coupling of Isonitriles with Carboxylic Acids To Form 2,4,5-Trisubstituted Oxazoles

Y. Odabachian; S. Tong; Q. Wang; M-X. Wang; J. Zhu 

From natural product to marketed drug: the tiacumicin odyssey

W. Erb; J. Zhu 

Iron Chloride-Catalyzed Three-Component Domino Sequences: Syntheses of Functionalized α-Oxy-N-acylhemiaminals and α-Oxyimides

F. Drouet; J. Zhu; G. Masson 

Palladium-Catalyzed Decarboxylative Vinylation of Potassium Nitrophenyl Acetate: Application to the Total Synthesis of (±)-Goniomitine

Z. Xu; Q. Wang; J. Zhu 

Synthesis of Iminonitriles by Oxone/TBAB-Mediated One-Pot Oxidative Three-Component Strecker Reaction

J-B. Gualtierotti; X. Schumacher; Q. Wang; J. Zhu 

Palladium(II)-Catalyzed Cyclizative Cross-Coupling of ortho-Alkynylanilines with ortho-Alkynylbenzamides under Aerobic Conditions

B. Yao; Q. Wang; J. Zhu 

Ugi Four-Component Reaction of Alcohols: Stoichiometric and Catalytic Oxidation/MCR Sequences

F. Drouet; G. Masson; J. Zhu 

Tertiary Amines as Synthetic Equivalents of Vinyl Cations: Zinc Bromide Promoted Coupling of Propargylamines with α-Isocyanoacetamides To Give 2,4,5-Trisubstituted Oxazoles Initiated by an Internal Redox Process

Y. Odabachian; Q. Wang; J. Zhu 

Enantioselective Total Syntheses of Leuconolam–Leuconoxine–Mersicarpine Group Monoterpene Indole Alkaloids

Z. Xu; Q. Wang; J. Zhu 

Chemical Functionalization of Bioceramics for the Development of Bone Implants

Surface Modification of Biomaterials for Conjugation with Human Fetal Osteoblasts

F. Borcard; P. Kong; C. Journot; D. Staedler; P. N. Sturzenegger et al. 

Convenient synthesis of heterobifunctional poly(ethylene glycol) suitable for the functionalization of iron oxide nanoparticles for biomedical applications

S. Passemard; D. Städler; L. Ucnova; G. S. Schneiter; P. Kong et al. 

Lack of Enantioselectivity in the SULT1A3-catalyzed Sulfoconjugation of Normetanephrine Enantiomers: An In Vitro and Computational Study

E. Grouzmann; J-B. Gualtierotti; S. Gerber-Lemaire; K. Abid; N. Brakch et al. 

Synthesis of bone-like structured foams

F. Krauss Juillerat; R. Engeli; I. Jerjen; P. N. Sturzenegger; F. Borcard et al. 

Total Synthesis and Biological Evaluation of Jerantinine E

R. Frei; D. Städler; A. Raja; R. Franke; F. Sasse et al. 

Enantioselctive Passerini Reaction

Total Synthesis of Natural Products and the Synergy with Synthetic Methodology

Enantioselective Synthesis of 4-Hydroxytetrahydropyridine Derivatives by Intramolecular Addition of Tertiary Enamides to Aldehydes

S. Tong; D-X. Wang; L. Zhao; J. Zhu; M-X. Wang 

Amidation of Aldehydes and Alcohols through α-Iminonitriles and a Sequential Oxidative Three-Component Strecker Reaction/Thio-Michael Addition/Alumina-Promoted Hydrolysis Process to Access β-Mercaptoamides from Aldehydes, Amines, and Thiols

J-B. Gualtierotti; X. Schumacher; P. Fontaine; G. Masson; Q. Wang et al. 

Exploiting the Divergent Reactivity of Isocyanoacetates: One-Pot Three-Component Synthesis of Functionalized Angular Furoquinolines

M. J. Bouma; G. Masson; J. Zhu 

Copper Catalyzed N-Arylation of Amidines with Aryl Boronic Acids and One-Pot Synthesis of Benzimidazoles by a Chan–Lam–Evans N-Arylation and C–H Activation/C–N Bond Forming Process

J. Li; S. Bénard; L. Neuville; J. Zhu 

Synergistic Effect of Palladium and Copper Catalysts: Catalytic Cyclizative Dimerization of ortho-(1-Alkynyl)benzamides Leading to Axially Chiral 1,3-Butadienes

B. Yao; C. Jaccoud; Q. Wang; J. Zhu 

Synthesis, Biological Evaluation, and Molecular Modeling of Natural and Unnatural Flavonoidal Alkaloids, Inhibitors of Kinases

T. B. Nguyen; O. Lozach; G. Surpateanu; Q. Wang; P. Retailleau et al. 

Palladium(II)-Catalyzed Intramolecular Diamination of Alkynes under Aerobic Oxidative Conditions: Catalytic Turnover of an Iodide Ion

B. Yao; Q. Wang; J. Zhu 

A Concise Total Synthesis of (±)-Trigonoliimine B

T. Buyck; Q. Wang; J. Zhu 

PRACTICAL SYNTHESIS OF N-ARYL-o-HYDROXYARYL KETIMINES

T. B. Nguyen; Q. Wang; F. Gueritte 

Synthesis of 4-amino-1,2,3,4-tetrahydropyridine derivatives by intramolecular nucleophilic addition of tertiary enamides to in-situ generated imines

S. Tong; X. Yang; D-X. Wang; L. Zhao; J. Zhu et al. 

Chiral Phosphoric Acid-Catalyzed Enantioselective Three-Component Povarov Reaction Using Cyclic Enethioureas as Dienophiles: Stereocontrolled Access to Enantioenriched Hexahydropyrroloquinolines

G. Dagousset; P. Retailleau; G. Masson; J. Zhu 

Organocatalytic Enantioselective One-Pot Four-Component Ugi-Type Multicomponent Reaction for the Synthesis of Epoxy-tetrahydropyrrolo[3,4-

Y. Su; M. J. Bouma; L. Alcaraz; M. Stocks; M. Furber et al. 

Palladium-Catalyzed Coupling of ortho-Alkynylanilines with Terminal Alkynes Under Aerobic Conditions: Efficient Synthesis of 2,3-Disubstituted 3-Alkynylindoles

B. Yao; Q. Wang; J. Zhu 

Un nouveau venu dans la lutte contre le Clostridium difficile: Les antibiotiques accueillent un nouveau membre

W. Erb; J. Zhu 

Spirocyclization by Palladium-Catalyzed Domino Heck–Direct C–H Arylation Reactions: Synthesis of Spirodihydroquinolin-2-ones

T. Piou; L. Neuville; J. Zhu 

Development and Application of Isocyanide-based Multicomponent Reactions

Synthesis of Indoles by Copper-Catalyzed Heteroannulation of o-Aminophenylboronic Acid Pinacol Esters with β-Keto Esters

A. Bunescu; Q. Wang; J. Zhu 

Activation of a C(sp3)H Bond by a Transient s-Alkylpalladium(II) Complex: Synthesis of Spirooxindoles Through a Palladium-Catalyzed Domino Carbopalladation/C(sp3)C(sp3) Bond-Forming Process

T. Piou; L. Neuville; J. Zhu 

Functionalization of microstructured open-porous bio-ceramic scaffolds with human fetal cells

F. Krauss Juillerat; F. Borcard; D. Staedler; C. Scaletta; L. A. Applegate et al. 

Chemical functionalization of bio-ceramics to enhance endothelial cells adhesion for tissue engineering

F. Borcard; D. Staedler; H. Comas; F. Krauss Juillerat; P. N. Sturzenegger et al. 

Surface Functionalisation of Alumina Ceramic Foams with Organic Ligands

H. Comas; V. Laporte; F. Borcard; P. Miéville; F. Krauss Juillerat et al. 

Harmonic Nanocrystals for Bio-Labeling: a Survey of Optical Properties and Biocompatibility

D. Staedler; T. Magouroux; R. Hadji; C. Joulaud; J. Extermann et al. 

Synthetic calibrators for the analysis of sulfoconjugated metanephrines in urine: hydrolysis conditions revisited

J. Simonin; S. Gerber-Lemaire; C. Centeno; C. Seghezzi; K. Iglesias et al. 

Built-in 5-Aminooxazole as an Internal Activator of the Terminal Carboxylic Acid: An Alternative Access to Macrocyclodepsipeptides

J. Zhu 

Cinchona Alkaloid-Amides Catalyzed Enantioselective Formal [2+2] Cycloadditions of Allenoates and Imines: Enantioselective Synthesis of 2,4-Substituted Azetidines

J-B. Denis; G. Masson; P. Retailleau; J. Zhu 

Unexpected C–C Bond Cleavage: Synthesis of 1,2,4-Oxadiazol-5-ones from Amidoximes with Pentafluorophenyl or Trifluoromethyl Anion Acting as Leaving Group

T. Gerfaud; H-L. Wei; L. Neuville; J. Zhu 

Synthesis of Hydroxylated 3,4-Dihydropyridine-2-ones from Intramolecular Nucleophilic Addition Reaction of Oxirane-containing Tertiary Enamides

L. Yang; S. Tong; D-X. Wang; Z-T. Huang; J. Zhu et al. 

Trifluoroacetic Acid-Promoted Synthesis of 3-Hydroxy, 3-Amino and Spirooxindoles from α-Keto-N-Anilides

I. Gorokhovik; L. Neuville; J. Zhu 

Chiral Calcium Organophosphate-Catalyzed Enantioselective Electrophilic Amination of Enamides

F. Drouet; C. Lalli; H. Liu; G. Masson; J. Zhu 

A Practical, One-Pot Multicomponent Synthesis of α-Amidosulfides and Their Application as Latent N-Acylimines in the Friedel-Crafts Reaction

N. George; M. Bekkaye; G. Masson; J. Zhu 

Access to Macrocycles with an endo Aryl ether and an endo Aryl-Aryl Bond, Development and Application

Q. Wang; J. Zhu 

Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation of N-Aryl-ortho-Hydroxybenzophenone Ketimines

T. B. Nguyen; H. Bousserouel; Q. Wang; F. Guéritte 

An Efficient One-Step Synthesis of Piperidin-2-yl and Pyrrolidin-2-yl Flavonoid Alkaloids through Phenolic Mannich Reactions

T. B. Nguyen; Q. Wang; F. Gueritte 

Protecting-Group-Free Total Synthesis of (E) and (Z)-Alstoscholarine

T. Gerfaud; C. Xie; L. Neuville; J. Zhu 

Iodo-Carbocyclization of Electron-Deficient Alkenes: Synthesis of Oxindoles and Spirooxindoles

H-L. Wei; T. Piou; J. Dufour; L. Neuville; J. Zhu 

Asymmetric Synthesis of 2,4,6-Trideoxy-4-(dimethylamino)-3-C-methyl-Llyxohexopyranose (Lemonose)

G. Bernadat; N. George; C. Couturier; G. Masson; T. Schlama et al. 

Chiral Phosphoric Acid-Catalyzed Enantioselective Three-Component Povarov Reaction Using Enecarbamates as Dienophiles: Highly Diastereo- and Enantioselective Synthesis of Substituted 4-Aminotetrahydroquinolines

G. Dagousset; J. Zhu; G. Masson 

Chiral Phosphoric Acid Catalyzed Enantioselective Transfer Hydrogenation of ortho-Hydroxybenzophenone N-H Ketimines and Applications

T. B. Nguyen; Q. Wang; F. Guéritte 

Exploiting the Divergent Reactivity of a-Isocyanoacetate: Multicomponent Synthesis of 5-Alkoxyoxazoles and Related Heterocycles

C. Lalli; M. J. Bouma; D. Bonne; G. Masson; J. Zhu 

A spinning thermometer to monitor microwave heating and glass transitions in dynamic nuclear polarization

P. Miéville; V. Vitzthum; M. A. Caporini; S. Jannin; S. Gerber-Lemaire et al. 

Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers

G. Coste; T. Horlacher; L. Molina; A. J. Moreno-Vargas; A. T. Carmona et al. 

Chemical Developments in DNP-NMR

Covalent cell surface functionalization of human fetal osteoblasts for tissue engineering

F. Borcard; A. Godinat; D. Städler; H. Comas Blanco; A-L. Dumont et al. 

Fractional Spin-Labeling of Polymers for Enhancing NMR Sensitivity by Solvent-Free Dynamic Nuclear Polarization

V. Vitzthum; F. Borcard; S. Jannin; M. Morin; P. Miéville et al. 

Asymmetric Morita–Baylis–Hillman Reaction and Its Aza Analogue

Total synthesis of complestatin (Chloropeptin II)

Z. Wang; M. Bois-Choussy; Y. Jia; J. Zhu 

1-Isocyano-2-nitrobenzene

1-(2,2-Dimethoxyethyl)-2-isocyanobenzene

Efficient Synthesis of alpha -Ketoamides via 2-Acyl-5-aminooxazoles by Reacting Acyl Chlorides and alpha -Isocyanoacetamides

R. Mossetti; T. Pirali; G. C. Tron; J. Zhu 

Intramolecular Suzuki-Miyaura reaction for the total synthesis of signal peptidase inhibitors, arylomycins A2 and B2

J. Dufour; L. Neuville; J. Zhu 

Palladium-Catalyzed Carbo-Heterofunctionalization of Alkenes for the Synthesis of Oxindoles and Spirooxindoles

S. Jaegli; J. Dufour; H-l. Wei; T. Piou; X-H. Duan et al. 

Zinc Chloride Promoted Formal Oxidative Coupling of Aromatic Aldehydes and Isocyanides to alpha -Ketoamides

M. Bouma; G. Masson; J. Zhu 

Palladium-catalyzed domino Heck/cyanation: synthesis of 3-cyanomethyloxindoles and their conversion to spirooxoindoles

S. Jaegli; J-P. Vors; L. Neuville; J. Zhu 

Passerini Three-Component Reaction of Alcohols under Catalytic Aerobic Oxidative Conditions

J. Brioche; G. Masson; J. Zhu 

Multicomponent Syntheses of Macrocycles

Copper-promoted N-cyclopropylation of anilines and amines by cyclopropylboronic acid

S. Benard; L. Neuville; J. Zhu 

Chiral Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation of ortho-Hydroxyaryl Alkyl N-H Ketimines

T. B. Nguyen; H. Bousserouel; Q. Wang; F. Guéritte 

1-Isocyanocyclohex-1-ene

Enantioselective Aza-Morita-Baylis-Hillman Reaction Using Aliphatic alpha -Amidosulfones as Imine Surrogates

N. Abermil; G. Masson; J. Zhu 

Palladium-Catalyzed Domino Process to Spirooxindoles: Ligand Effect on Aminopalladation versus Carbopalladation

S. Jaegli; W. Erb; P. Retailleau; J-P. Vors; L. Neuville et al. 

Studies toward new anti-cancer strategies based on alpha-mannosidase inhibition

S. Gerber-Lemaire; L. Juillerat-Jeanneret 

Inhibitors of prolyl-oligopeptidases for the therapy of human diseases: defining diseases and inhibitors

J. Lawandi; S. Gerber-Lemaire; L. Juillerat-Jeanneret; N. Moitessier 

Scavenging Free Radicals To Preserve Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear Polarization

P. Miéville; P. Ahuja; R. Sarkar; S. Jannin; P. R. Vasos et al. 

Chiral Bronsted Acid-Catalyzed Enantioselective Three-Component Povarov Reaction

H. Liu; G. Dagousset; G. Masson; P. Retailleau; J. Zhu 

Chiral Bronsted Acid-Catalyzed Enantioselective Multicomponent Mannich Reaction: Synthesis of anti-1,3-Diamines Using Enecarbamates as Nucleophiles

G. Dagousset; F. Drouet; G. Masson; J. Zhu 

Synthetic Studies on (-)-Lemonomycin: An Efficient Asymmetric Synthesis of Lemonomycinone Amide

Y-C. Wu; G. Bernadat; G. Masson; C. Couturier; T. Schlama et al. 

IBX/TBAB-mediated oxidation of primary amines to nitriles

F. Drouet; P. Fontaine; G. Masson; J. Zhu 

Invertible Enantioselectivity in 6′-Deoxy-6′-acylamino-beta -isocupreidine-Catalyzed Asymmetric Aza-Morita-Baylis-Hillman Reaction: Key Role of Achiral Additive

N. Abermil; G. Masson; J. Zhu 

Asymmetric Total Syntheses of (-)-Renieramycin M and G and (-)-Jorumycin Using Aziridine as a Lynchpin

Y-C. Wu; J. Zhu 

Synthesis of Pyrroles by Consecutive Multicomponent Reaction/[4 + 1] Cycloaddition of alpha -Iminonitriles with Isocyanides

P. Fontaine; G. Masson; J. Zhu 

Palladium-catalyzed annulation of acyloximes with arynes (or alkynes): synthesis of phenanthridines and isoquinolines

T. Gerfaud; L. Neuville; J. Zhu 

Ugi-post functionalization, from a single set of Ugi-adducts to two distinct heterocycles by microwave-assisted palladium-catalyzed cyclizations: tuning the reaction pathways by ligand switch

W. Erb; L. Neuville; J. Zhu 

Catalytic Asymmetric Passerini-Type Reaction: Chiral Aluminum-Organophosphate-Catalyzed Enantioselective alpha -Addition of Isocyanides to Aldehydes

T. Yue; M-X. Wang; D-X. Wang; G. Masson; J. Zhu 

Palladium-catalyzed domino N-arylation/carbopalladation/C-H functionalization: three-component synthesis of 3-(diarylmethylene)oxindoles

A. Pinto; L. Neuville; J. Zhu 

Combination of lithium chloride and hexafluoroisopropanol for Friedel-Crafts reactions

M. Willot; J. C. Chen; J. Zhu 

Total synthesis of horsfiline: a palladium-catalyzed domino Heck-cyanation strategy

S. Jaegli; J-P. Vors; L. Neuville; J. Zhu 

Synthesis of L-3-hydroxy-4-methoxy-5-methylphenylalanol

N. Demoulin; J. Zhu 

Bronsted Acid Catalyzed Enantioselective Three-Component Reaction Involving the alpha Addition of Isocyanides to Imines

T. Yue; M-X. Wang; D-X. Wang; G. Masson; J. Zhu 

Palladium-Catalyzed Intramolecular C-Arylation of Benzylic Carbon: Synthesis of 3-Benzoxazolylisoindolinones by a Sequence of Ugi-4CR/Postfunctionalization

A. Salcedo; L. Neuville; J. Zhu 

Copper-Mediated N-Cyclopropylation of Azoles, Amides, and Sulfonamides by Cyclopropylboronic Acid

S. Benard; L. Neuville; J. Zhu 

Asymmetric Total Synthesis of (-)-Quinocarcin

Y-C. Wu; M. Liron; J. Zhu 

Asymmetric synthesis of 5-(1-hydroxyalkyl)tetrazoles by catalytic enantioselective Passerini-type reactions

T. Yue; M-X. Wang; D-X. Wang; J. Zhu 

Highly Enantioselective Aza Morita-Baylis-Hillman Reaction Catalyzed by Bifunctional beta -Isocupreidine Derivatives

N. Abermil; G. Masson; J. Zhu 

Synthesis of diastereomers of complestatin and chloropeptin I: substrate-dependent atropstereoselectivity of the intramolecular Suzuki-Miyaura reaction

Y. Jia; M. Bois-Choussy; J. Zhu 

Hafnium Trifluoromethanesulfonate (Hafnium Triflate) as a Highly Efficient Catalyst for Chemoselective Thioacetalization and Transthioacetalization of Carbonyl Compounds

Y-C. Wu; J. Zhu 

Catalytic enantioselective Passerini three-component reaction

S-X. Wang; M-X. Wang; D-X. Wang; J. Zhu 

One-Pot Three-Component Synthesis of alpha -Iminonitriles by IBX/TBAB-Mediated Oxidative Strecker Reaction

P. Fontaine; A. Chiaroni; G. Masson; J. Zhu 

Total synthesis of arylomycin A2, a signal peptidase I (SPase I) inhibitor

J. Dufour; L. Neuville; J. Zhu 

Synthesis of dihydrophenanthridines by a sequence of Ugi-4CR and palladium-catalyzed intramolecular C-H functionalization

F. Bonnaterre; M. Bois-Choussy; J. Zhu 

Palladium-Catalyzed Domino Intramolecular N-Arylation/Intermolecular C-C Bond Formation for the Synthesis of Functionalized Benzodiazepinediones

A. Salcedo; L. Neuville; C. Rondot; P. Retailleau; J. Zhu 

Synthesis of alpha -keto amides by a molecular-sieves-promoted formal oxidative coupling of aliphatic aldehydes with isocyanides

J-M. Grassot; G. Masson; J. Zhu 

Development of multicomponent and domino reactions based on alpha -isocyanoacetamide and 5-aminooxazole

G. Masson; L. Neuville; J. Zhu 

Bicyclic 5-5 Systems with One Bridgehead (Ring Junction) Nitrogen Atom: Four Extra Heteroatoms 2:2

Chiral Salen-Aluminum Complex as a Catalyst for Enantioselective alpha -Addition of Isocyanides to Aldehydes: Asymmetric Synthesis of 2-(1-Hydroxyalkyl)-5-aminooxazoles

S-X. Wang; M-X. Wang; D-X. Wang; J. Zhu 

Preparation of ecteinascidin alkaloids, such as ecteinascidins 583 and 597

J. Zhu; M. Bois-Choussy; J. Chen; X. Chen 

Highly Efficient and Stereoselective N-Vinylation of Oxiranecarboxamides and Unprecedented 8-endo-Epoxy-arene Cyclization: Expedient and Biomimetic Synthesis of Some Clausena Alkaloids

L. Yang; G. Deng; D-X. Wang; Z-T. Huang; J-P. Zhu et al. 

New Frontiers in Asymmetric Catalysis edited by Koichi Mikami and Mark Lautens

J. Zhu 

Palladium-catalyzed enantioselective domino Heck-cyanation sequence: development and application to the total synthesis of esermethole and physostigmine

A. Pinto; Y. Jia; L. Neuville; J. Zhu 

The enantioselective Morita-Baylis-Hillman reaction and its aza counterpart

G. Masson; C. Housseman; J. Zhu 

Modulating the reactivity of alpha -isocyanoacetates: multicomponent synthesis of 5-methoxyoxazoles and furopyrrolones

D. Bonne; M. Dekhane; J. Zhu 

Palladium-catalyzed three-component synthesis of 3-(diarylmethylene)oxindoles through a domino Sonogashira/carbopalladation/C-H activation/C-C bond-forming sequence

A. Pinto; L. Neuville; J. Zhu 

Rapid synthesis of cyclodepsipeptides containing a sugar amino acid or a sugar amino alcohol by a sequence of a multicomponent reaction and acid-mediated macrocyclization

C. Bughin; G. Masson; J. Zhu 

Synthesis of DEFG ring of complestatin and chloropeptin I: highly atropdiastereoselective macrocyclization by intramolecular Suzuki-Miyaura reaction

Y. Jia; M. Bois-Choussy; J. Zhu 

Total synthesis of the marine natural product (-)-cribrostatin 4 (renieramycin H)

X. Chen; J. Zhu 

Asymmetric Lewis acid catalyzed addition of isocyanides to aldehydes. Synthesis of 5-amino-2-(1-hydroxyalkyl)oxazoles

S. Wang; M-X. Wang; D-X. Wang; J. Zhu 

Lithium bromide-promoted three-component synthesis of oxa-bridged tetracyclic tetrahydroisoquinoline derivatives

A. Fayol; E. Gonzalez-Zamora; M. Bois-Choussy; J. Zhu 

Synthesis of Protected Chiral Vicinal Diaminoalcohols by Diastereoselective Intramolecular Benzylic Substitution from Bistrichloroacetimidates

C. Rondot; P. Retailleau; J. Zhu 

Ammonium Chloride Promoted Three-Component Synthesis of 5-Iminooxazoline and Its Subsequent Transformation to Macrocyclodepsipeptide

T. Pirali; G. C. Tron; G. Masson; J. Zhu 

IBX-mediated oxidative Ugi-type multicomponent reactions: application to the N and C1 functionalization of tetrahydroisoquinoline

T. Ngouansavanh; J. Zhu 

Synthetic studies on ecteinascidin 743 (Et 743): asymmetric synthesis of a highly oxygenated tetrahydroisoquinoline via a key phenolic Mannich reaction

X. Chen; J. Chen; J. Zhu 

5-aminooxazole as an internal traceless activator of C-terminal carboxylic acid: rapid access to diversely functionalized cyclodepsipeptides

C. Bughin; G. Zhao; H. Bienayme; J. Zhu 

Importance of the structure of vancomycin binding pocket in designing compounds active against vancomycin-resistant enterococci (VRE)

Y. Jia; M. Bois-Choussy; A. Malabarba; C. Brunati; J. Zhu 

Synthesis of 4-nitrophenyl sulfones and application in the modified Julia olefination

D. Mirk; J-M. Grassot; J. Zhu 

Preparation of beta-amino or alpha ,beta-diamino esters derived from serine

J. Zhu; C. Couturier; J. Blanchet 

Asymmetric total syntheses of ecteinascidin 597 and ecteinascidin 583

J. Chen; X. Chen; M. Willot; J. Zhu 

One-pot synthesis of macrocycles by a tandem three-component reaction and intramolecular [3+2] cycloaddition

T. Pirali; G. C. Tron; J. Zhu 

Rapid synthesis of cyclopeptide alkaloid-like para-cyclophanes by combined use of Ugi-4CR and intramolecular SNAr reaction

P. Cristau; J-P. Vors; J. Zhu 

Rapid access to oxindoles by the combined use of an Ugi four-component reaction and a microwave-assisted intramolecular Buchwald-Hartwig amidation reaction

F. Bonnaterre; M. Bois-Choussy; J. Zhu 

Aziridinium from N,N-dibenzyl serine methyl ester: Synthesis of enantiomerically pure beta -amino and alpha ,beta -diamino esters

C. Couturier; J. Blanchet; T. Schlama; J. Zhu 

Design and synthesis of simple macrocycles active against vancomycin-resistant Enterococci (VRE)

Y. Jia; N. Ma; Z. Liu; M. Bois-Choussy; E. Gonzalez-Zamora et al. 

Synthetic studies towards (-)-lemonomycin, synthesis of fused tetracycles

C. Couturier; T. Schlama; J. Zhu 

Mono alkylation of alpha -isocyano acetamide to its higher homologues

C. Housseman; J. Zhu 

Palladium-Catalyzed, Modular Synthesis of Highly Functionalized Indoles and Tryptophans by Direct Annulation of Substituted o-Haloanilines and Aldehydes

Y. Jia; J. Zhu