Publications

The full list of publications can be downloaded here.

2024

  • Mombelli E, Osypenko D, Palchaudhuri S, Sourmpis C, Brea J, Kochubey O and Schneggenburger R (2024). Auditory stimuli suppress contextual fear responses in safety learning independent of a possible safety meaning. Front Behav Neurosci 18:1415047 [Link to Journal] (PDF)

2023

  • Kintscher M, Kochubey O, Schneggenburger R (2023). A striatal circuit balances learned fear in the presence and absence of sensory cues. eLife 12:e75703 [Link to Journal] (PDF)

2022

  • Palchaudhuri S, Osypenko D, Schneggenburger R (2022). Fear Learning: An Evolving Picture for Plasticity at Synaptic Afferents to the Amygdala. The Neuroscientist. July 2022 [Link to Journal] (PDF)
  • Baleisyte A, Schneggenburger R, Kochubey O (2022). Stimulation of medial amygdala GABA neurons with kinetically different channelrhodopsins yields opposite behavioral outcomes. Cell Rep 39(8):110850. [Link to Journal] (PDF)

2021

  • Perino A, Velázquez-Villegas LA, Bresciani N, Sun Y, Huang Q, Fénelon VS, Castellanos-Jankiewicz A, Zizzari P, Bruschetta G, Jin S, Baleisyte A, Gioiello A, Pellicciari R, Ivanisevic J, Schneider BL, Diano S, Cota D and Schoonjans K  (2021). Central anorexigenic actions of bile acids are mediated by TGR5. Nat Metab; 3:595–603. [Link to Journal]

2020

  • Lozano-Montes L, Dimanico M, Mazloum R, Li W, Nair J,  Kintscher M, Schneggenburger R, Harvey M, Rainer G (2020). Optogenetic Stimulation of Basal Forebrain Parvalbumin Neurons Activates the Default Mode Network and Associated Behaviors. Cell Rep 33(6): 108359. [Link to Journal] (PDF)
  • Vickers ED, Osypenko D, Clark C, Okur Z, Scheiffele P, Schneggenburger R (2020). LTP of inhibition at PV interneuron output synapses requires developmental BMP signaling. Sci Rep 10: 10047. [Link to Journal] [Link to dataset] (PDF)
  • Tang W, Kochubey O, Kintscher M, Schneggenburger R (2020). A VTA to basal amygdala dopamine projection contributes to signal salient somatosensory events during fear learning. J Neurosci; 40(20):3969-3980. [Link to Journal] [Link to dataset] (PDF)

2019

  • Retraction: Berret E, Kintscher M, Palchaudhuri S, Tang W, Osypenko D, Kochubey O, Schneggenburger R (2019). Insular cortex processes aversive somatosensory information and is crucial for threat learning. Science 366(6472):1460. [Link to Journal]      
  • Kronander E, Clark C, Schneggenburger R (2019). Role of BMP signaling for the formation of auditory brainstem nuclei and large auditory relay synapses. Dev. Neurobiol; 79(2):155-174. [Link to Journal] [Full text]

2018

  • Bacq A, Astori S, Gebara E, Tang W, Silva BA, Sanchez-Mut J, Grosse J, Guillot de Suduiraut I, Zanoletti O, Maclachlan C, Knott GW, Gräff J, Sandi C (2018). Amygdala GluN2B-NMDAR dysfunction is critical in abnormal aggression of neurodevelopmental origin induced by St8sia2 deficiency. Mol Psychiatry [Link to Journal] [Full text]
  • Vickers ED, Clark C, Osypenko D, Fratzl A, Kochubey O, Bettler B, Schneggenburger R. (2018). Parvalbumin-Interneuron Output Synapses Show Spike-Timing-Dependent Plasticity that Contributes to Auditory Map Remodeling. Neuron; 99(4):720-735.e6. [Link to journal]
  • Gjoni E, Aguet C, Sahlender DA, Knott G, Schneggenburger R. (2018). Ultrastructural basis of strong unitary inhibition in a binaural neuron. J Physiol; 596(20):4969-4982. [Link to journal] [Full text]
  • Gjoni E, Zenke F, Bouhours B, Schneggenburger R. (2018). Specific synaptic input strengths determine the computational properties of excitation – inhibition integration in a sound localization circuit. J Physiol; 596(20):4945-4967. [Link to journal][Full text]

2017

  • Kronander E, Michalski N, Lebrand C, Hornung J-P & Schneggenburger R. (2017). An organotypic slice culture to study the formation of calyx of Held synapses in-vitro. PLoS One;12(4): e0175964 [Link to journal] (PDF)
  • Bouhours B, Gjoni E, Kochubey O & Schneggenburger R. (2017). Synaptotagmin2 (Syt2) drives fast release redundantly with Syt1 at the output synapses of Parvalbumin-expressing inhibitory neurons. J Neurosci; 37(17): 4604-4617 [Link to journal] (PDF)

2016

  • Kochubey O, Babai N, Schneggenburger R. (2016). A Synaptotagmin Isoform Switch during the Development of an Identified CNS Synapse. Neuron 90(5):984-999. [Link to journal] (PDF)

2015

  • Keller D., Babai N., Kochubey O., Han Y., Markram H., Schürmann F. and Schneggenburger R. (2015). An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse. PLoS Comput Biol 11, e1004253 [Link to journal] [Full text]
  • Schneggenburger R. and Rosenmund C. (2015). Molecular mechanisms governing Ca2+ regulation of evoked and spontaneous release. Nat Neurosci 18, 935-941 [Link to journal] (PDF)
  • Han Y., Babai N., Kaeser P., Südhof T., Schneggenburger R. (2015). RIM1 and RIM2 redundantly determine Ca2+ channel density and readily-releasable pool size at a large hindbrain synapse. J Neurophysiol., 2015 Jan 1;113(1):255-63 [Link to journal] [Full text]

2014

  • Babai N., Kochubey O., Keller D., Schneggenburger R. (2014). An alien divalent ion reveals a major role for Ca2+ buffering in controlling slow transmitter release. J Neurosci;34(38):12622-35. [Link to journal] (PDF)
  • Genç O, Kochubey O, Toonen RF, Verhage M, Schneggenburger R. (2014) Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release. eLife;3:e01715 [Link to journal] [Full text]

2013

  • Xiao L., Michalski N., Kronander E., Gjoni E., Genoud C., Knott G., Schneggenburger R. (2013) BMP-signaling specifies the development of a large and fast CNS synapse. Nat Neurosci.16(7): 856-64 [Link to journal]
  • Michalski N., Babai N., Renier N., Perkel D.J., Chédotal A., Schneggenburger R. (2013) Robo3-Driven Axon Midline Crossing Conditions Functional Maturation of a Large Commissural Synapse. Neuron 78(5): 855-68 [Link to journal]

2012

  • Schneggenburger R., Han Y., Kochubey O. (2012) Ca2+ channels and transmitter release at the active zone. Cell Calcium 52(3-4):199-207 [Link to journal]
  • Gaugler M.N., Genc O., et al. (2012) Nigrostriatal overabundance of alpha-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity. Acta Neuropathol. 123(5):653-69 [Link to journal]

2011

  • Kochubey O., Lou X., Schneggenburger R. (2011) Regulation of transmitter release by Ca2+ and synaptotagmin: insights form a large CNS synapse. Trends Neurosci. 34(5): 237-246 [Link to journal]
  • Kochubey O., Schneggenburger R. (2011) Synaptotagmin increases the dynamic range of synapses by driving Ca2+-evoked release and by clamping a near-linear remaining Ca2+ sensor. Neuron 69(4):736-48 [Link to journal] (PDF)
  • Han Y., Kaeser P.S., Südhof T.C., Schneggenburger R. (2011) RIM determines Ca2+ channel density and vesicle docking at the presynaptic active zone. Neuron 69(2):304-16 [Link to journal] [Full text]
  • Dusonchet J., Kochubey O., Stafa K., Young S.M. Jr, Zufferey R., Moore D.J., Schneider B.L., Aebischer P. (2011) A rat model of progressive nigral neurodegeneration induced by the parkinson’s disease-associated G2019S mutation in LRRK2. J Neurosci. 31(3):907-12 [Link to journal] (PDF)

2010

  • Müller M., Goutman J.D., Kochubey O., Schneggenburger R. (2010) Interaction between facilitation and depression at a large CNS synapse reveals mechanisms of short-term plasticity. J Neurosci. 30(6): 2007-2016. [Link to journal] (PDF)
  • Xiao L., Han Y., Runne H., Murray H., Kochubey O., Lüthi-Carter R. and Schneggenburger R. (2010) Developmental expression of Synaptotagmin isoforms in single calyx of Held-generating neurons. Mol Cell Neurosci. 44(4): 374-85. [Link to journal] (PDF)
  • Beurg M., Michalski N., Safieddine S., Bouleau Y., Schneggenburger R., Chapman E.R., Petit C., Dulon D. (2010) Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells. J Neurosci. 30(40): 13281-90. [Link to journal] (PDF)

2009

  • Kochubey O., Han Y., Schneggenburger R. (2009) Developmental regulation of the intracellular Ca2+sensitivity of vesicle fusion and Ca2+ -secretion coupling at the rat calyx of Held. J Physiol. 587(Pt 12):3009-23. [Link to journal] [Full text]

2008

  • Lou X., Korogod N., Brose N., Schneggenburger R. (2008) Phorbol esters modulate spontaneous and Ca2+ -evoked transmitter release via acting on both Munc13 and protein kinase C. J Neurosci. 28(33):8257-67 [Link to journal] (PDF)
  • Müller M., Felmy F., Schneggenburger R. (2008) A limited contribution of Ca2+ current facilitation to paired-pulse facilitation of transmitter release at the rat calyx of Held. J Physiol. 586(Pt 22):5503-20. [Link to journal] [Full text]
  • Schneggenburger, R. (2008) Exocytosis: Ca2+ sensitivity. The New Encyclopedia of Neuroscience, edited by Larry Squire et al., 2008.

2007

  • Müller M., Felmy F., Schwaller B., Schneggenburger R. (2007) Parvalbumin is a mobile presynaptic Ca2+ buffer in the calyx of held that accelerates the decay of Ca2+ and short-term facilitation. J Neurosci. 27(9):2261-71. [Link to journal] (PDF)
  • Wölfel M., Lou X., Schneggenburger R. (2007) A mechanism intrinsic to the vesicle fusion machinery determines fast and slow transmitter release at a large CNS synapse. J Neurosci. 27(12):3198-210. [Link to journal] (PDF)
  • Korogod N., Lou X., Schneggenburger R. (2007) Posttetanic potentiation critically depends on an enhanced Ca2+sensitivity of vesicle fusion mediated by presynaptic PKC. Proc Natl Acad Sci USA. 104(40):15923-8. [Link to journal] [Full text]

2006

  • Schneggenburger, R. (2006) Short-term plasticity: facilitation and post-tetanic potentiation In: Textbook of Neural repair and rehabilitation , ed. by M.E. Selzer, S. Clarke, L. Cohen, P.W. Duncan and F.H. Gage.
  • Schneggenburger, R. and Forsythe, I.F. (2006) The calyx of Held. Cell Tissue Res. 326: 311-337. [Link to journal]

2005

  • Korogod N., Lou X., Schneggenburger R. (2005) Presynaptic Ca2+requirements and developmental regulation of posttetanic potentiation at the calyx of Held. J Neurosci. 25(21):5127-37. [Link to journal] (PDF)
  • Lou X., Scheuss V., Schneggenburger R. (2005) Allosteric modulation of the presynaptic Ca2+sensor for vesicle fusion. Nature 435(7041):497-501. [Link to journal]
  • Kim M.H., Korogod N., Schneggenburger R., Ho W.K., Lee S.H. (2005) Interplay between Na+/Ca2+ exchangers and mitochondria in Ca2+clearance at the calyx of Held. J Neurosci. 25(26):6057-65. [Link to journal] (PDF)
  • Dulubova I., Lou X., Lu J., Huryeva I., Alam A., Schneggenburger R., Südhof T.C., Rizo J. (2005) A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? EMBO J. 24(16):2839-50. [Link to journal] [Full text]
  • Schneggenburger R. (2005) Ca2+uncaging in nerve terminals. In: Imaging In Neuroscience and Development; ed. by Rafael Yuste and Arthur Konnerth.
  • Schneggenburger R. & Neher E. (2005) Presynaptic calcium and control of vesicle fusion. Curr. Op. Neurobiol. 44: 266 – 274. [Link to journal]