PUBLICATIONS

Rescue of myocytes and locomotion through AAV2/9-2YF intracisternal gene therapy in a rat model of creatine transporter deficiency

G. Fernandes-Pires; M. D. Azevedo; M. Lanzillo; C. Roux-Petronelli; P-A. Binz et al. 

Molecular Therapy Methods & Clinical Development. 2024-06-13. Vol. 32, num. 2, p. 101251. DOI : 10.1016/j.omtm.2024.101251.

Diffusion of brain metabolites highlights altered brain microstructure in type C hepatic encephalopathy: a 9.4 T preliminary study

J. Mosso; G. Briand; K. Pierzchala; D. Simicic; A. Sierra et al. 

Frontiers In Neuroscience. 2024-03-20. Vol. 18, p. 1344076. DOI : 10.3389/fnins.2024.1344076.

Inhibition of urease-mediated ammonia production by 2-octynohydroxamic acid in hepatic encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

Nature Communications. 2024-03-12. Vol. 15, num. 1, p. 2226. DOI : 10.1038/s41467-024-46481-8.

Diffusion-weighted SPECIAL improves the detection of J-coupled metabolites at ultrahigh magnetic field

J. Mosso; D. Simicic; B. Lanz; R. Gruetter; C. Cudalbu 

Magnetic Resonance In Medicine. 2023-09-28. DOI : 10.1002/mrm.29805.

New Insights Into Brain Energy Metabolism in Type C Hepatic Encephalopathy: A Dual 18F-FDG PET and 9.4T 1H MRS Preclinical Study

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

2023-09-01. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S12-S12. DOI : 10.14309/01.ajg.0000948348.20966.21.

Automated segmentation and labeling of subcutaneous mouse implants at 14.1T

J. Adda; G. Bioley; D. van de Ville; C. Cudalbu; M. G. Preti et al. 

Frontiers In Signal Processing. 2023-08-21. Vol. 3, p. 1155618. DOI : 10.3389/frsip.2023.1155618.

Neurometabolic profiles of bile duct ligated rats after the treatment with an urease inhibitor – 1H MRS dataset

D. Evstafeva; J-C. Leroux; C. R. Cudalbu; D. Simicic 

2023.

Diffusion-weighted MR spectroscopy: Consensus, recommendations, and resources from acquisition to modeling

C. Ligneul; C. Najac; A. Doring; C. Beaulieu; F. Branzoli et al. 

Magnetic Resonance In Medicine. 2023-11-09. Vol. 91, num. 3, p. 860-885. DOI : 10.1002/mrm.29877.

Evaluation of a Hydroxamate-Based Urease Inhibitor in a Rodent Model of Hepatic Encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

2023-09-01. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S30-S31. DOI : 10.14309/01.ajg.0000948468.55577.45.

Brain Regional Differences in the Developing Brain Using an Animal Model of Type C Hepatic Encephalopathy

D. Simicic; K. Pierzchala; O. Braissant; C. Toso; G. Oldani et al. 

2023-09-01. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S24-S25. DOI : 10.14309/01.ajg.0000948428.52697.c3.

Age Dependence of Neurometabolic Changes in a Rat Pup Model of Type C Hepatic Encephalopathy

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

2023-09-01. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S24-S24. DOI : 10.14309/01.ajg.0000948424.84976.19.

The Beneficial Effect of Oral Cr Supplementation in an Early Childhood Rat Model of Chronic Hepatic Encephalopathy: In Vivo Longitudinal 1H and 31P Magnetic Resonance Spectroscopy Study

D. Simicic; O. Braissant; K. Pierzchala; S. Mitrea; D. Sessa et al. 

2023-09-01. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S12-S13. DOI : 10.14309/01.ajg.0000948352.71525.d3.

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

J. J. Mosso / R. Gruetter; C. R. Cudalbu (Dir.)  

Lausanne, EPFL, 2023. 

Lessons on brain edema in HE: from cellular to animal models and clinical studies

K. Pierzchala; A. Hadjihambi; J. Mosso; R. Jalan; C. F. F. Rose et al. 

Metabolic Brain Disease. 2023-08-22. DOI : 10.1007/s11011-023-01269-5.

Editorial for the special issue on Brain Biochemistry in Liver Disease

C. Cudalbu; A. J. L. Cooper 

Analytical Biochemistry. 2023-09-15. Vol. 677, p. 115248. DOI : 10.1016/j.ab.2023.115248.

High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study

C. Cudalbu; L. Xin; B. Marechal; S. Lachat; F. Zangas-Gheri et al. 

Analytical Biochemistry. 2023-07-04. Vol. 675, p. 115212. DOI : 10.1016/j.ab.2023.115212.

Central Nervous System Oxidative Stress interplay with inflammation in a rat model of Type C Hepatic Encephalopathy – brothers in arms?

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

2023-03-01. 1st international conference on the Future of Redox Biology, ITALY, Jun 17-19, 2022. p. S15-S15. DOI : 10.1016/j.freeradbiomed.2022.12.056.

Neurometabolic changes in a rat pup model of type C hepatic encephalopathy depend on age at liver disease onset

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

Metabolic Brain Disease. 2023-05-06. DOI : 10.1007/s11011-023-01210-w.

Harmonization of multi-scanner in vivo magnetic resonance spectroscopy: ENIGMA consortium task group considerations

A. D. Harris; H. Amiri; M. Bento; R. Cohen; C. R. K. Ching et al. 

Frontiers In Neurology. 2023-01-04. Vol. 13, p. 1045678. DOI : 10.3389/fneur.2022.1045678.

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy (vol 178, pg 295, 2022)

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Free Radical Biology And Medicine. 2022-03-01. Vol. 182, p. 289-289. DOI : 10.1016/j.freeradbiomed.2022.01.016.

MP-PCA denoising for diffusion MRS data: promises and pitfalls

J. Mosso; D. Simicic; K. Simsek; R. Kreis; C. Cudalbu et al. 

Neuroimage. 2022-11-01. Vol. 263, p. 119634. DOI : 10.1016/j.neuroimage.2022.119634.

Overview of oxidative stress findings in hepatic encephalopathy: From cellular and ammonium-based animal models to human data

D. Simicic; C. Cudalbu; K. Pierzchala 

Analytical Biochemistry. 2022-10-01. Vol. 654, p. 114795. DOI : 10.1016/j.ab.2022.114795.

Central Nervous System Oxidative Stress Interplay With Inflammation In A Rat Model Of Type C Hepatic Encephalopathy – Brothers In Arms?

P. Katarzyna; S. Dunja; S. Dario; M. Stefanita; B. Olivier et al. 

2022-08-20.  p. 40-40.

Advanced metabolite mapping at ultra-high field using 1H-MRS, 1H-MRSI and macromolecules: applications in a rat model of type C hepatic encephalopathy

D. Simicic / R. Gruetter; C. R. Cudalbu (Dir.)  

Lausanne, EPFL, 2022. 

Abnormal brain oxygen homeostasis in an animal model of liver disease

A. Hadjihambi; C. Cudalbu; K. Pierzchala; D. Simicic; C. Donnelly et al. 

Jhep Reports. 2022-08-01. Vol. 4, num. 8, p. 100509. DOI : 10.1016/j.jhepr.2022.100509.

PET CMRglc mapping and H-1-MRS show altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Analytical Biochemistry. 2022-06-15. Vol. 647, p. 114606. DOI : 10.1016/j.ab.2022.114606.

Quantitative FDG-PET and 1H-MRS reveal altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

2022-06-01.  p. 57-58.

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Free Radical Biology And Medicine. 2022-01-01. Vol. 178, p. 295-307. DOI : 10.1016/j.freeradbiomed.2021.12.011.

Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy

L. Duran-Trio; G. Fernandes-Pires; J. Grosse; I. Soro-Arnaiz; C. Roux-Petronelli et al. 

Journal Of Inherited Metabolic Disease. 2022. Vol. 45, num. 2, p. 278-291. DOI : 10.1002/jimd.12470.

Probiotics combined with rifaximin influence the neurometabolic changes in a rat model of type C HE

E. Flatt; V. A. McLin; O. Braissant; K. Pierzchala; P. Mastromarino et al. 

Scientific Reports. 2021-09-09. Vol. 11, num. 1, p. 17988. DOI : 10.1038/s41598-021-97018-8.

Hyperpolarized C-13-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

M. Mishkovsky; O. Gusyatiner; B. Lanz; C. Cudalbu; I. Vassallo et al. 

Scientific Reports. 2021-03-11. Vol. 11, num. 1, p. 5771. DOI : 10.1038/s41598-021-85339-7.

Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease

V. Rackayova; E. Flatt; O. Braissant; J. Grosse; D. Capobianco et al. 

Scientific Reports. 2021-01-26. Vol. 11, num. 1, p. 2269. DOI : 10.1038/s41598-021-81871-8.

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

C. Cudalbu; P. Bady; M. Lai; L. Xin; O. Gusyatiner et al. 

Acta Neuropathologica Communications. 2021-08-04. Vol. 9, num. 1, p. 133. DOI : 10.1186/s40478-021-01232-4.

In vivo macromolecule signals in rat brain 1 H‐MR spectra at 9.4T: Parametrization, spline baseline estimation, and T 2 relaxation times

D. Simicic; V. Rackayová; L. Xin; I. Tkáč; T. Borbath et al. 

Magnetic Resonance in Medicine. 2021-07-15. Vol. 86, num. 5, p. 2384-2401. DOI : 10.1002/mrm.28910.

The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery

M. G. Melo; N. Remacle; H-P. Cudre-Cung; C. Roux; M. Poms et al. 

Molecular Genetics And Metabolism. 2021-06-01. Vol. 133, num. 2, p. 157-181. DOI : 10.1016/j.ymgme.2021.03.017.

2021 ISHEN guidelines on animal models of hepatic encephalopathy

S. DeMorrow; C. Cudalbu; N. Davies; A. R. Jayakumar; C. F. Rose 

Liver International. 2021-05-11. Vol. 41, num. 7, p. 1474-1488. DOI : 10.1111/liv.14911.

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts’ consensus recommendations

A. Lin; O. Andronesi; W. Bogner; I-Y. Choi; E. Coello et al. 

Nmr In Biomedicine. 2021-02-09.  p. e4484. DOI : 10.1002/nbm.4484.

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

L. Duran-Trio; G. Fernandes-Pires; D. Simicic; J. Grosse; C. Roux-Petronelli et al. 

Scientific Reports. 2021. Vol. 11, num. 1, p. 1636. DOI : 10.1038/s41598-020-80824-x.

Late post‐natal neurometabolic development in healthy male rats using 1 H and 31 P Magnetic Resonance Spectroscopy

V. Račkayová; D. Simicic; G. Donati; O. Braissant; R. Gruetter et al. 

Journal of Neurochemistry. 2021. Vol. 157, num. 3, p. 508-519. DOI : 10.1111/jnc.15294.

Contribution of macromolecules to brain H-1 MR spectra: Experts’ consensus recommendations

C. Cudalbu; K. L. Behar; P. K. Bhattacharyya; W. Bogner; T. Borbath et al. 

Nmr In Biomedicine. 2020-11-25.  p. e4393. DOI : 10.1002/nbm.4393.

Magnetic resonance spectroscopy in the rodent brain: Experts’ consensus recommendations

B. Lanz; A. Abaei; O. Braissant; I-Y. Choi; C. Cudalbu et al. 

Nmr In Biomedicine. 2020-08-26.  p. e4325. DOI : 10.1002/nbm.4325.

B(0)shimming for in vivo magnetic resonance spectroscopy: Experts’ consensus recommendations

C. Juchem; C. Cudalbu; R. A. de Graaf; R. Gruetter; A. Henning et al. 

Nmr In Biomedicine. 2020-06-28.  p. e4350. DOI : 10.1002/nbm.4350.

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts’ consensus recommendations

R. Kreis; V. Boer; I-Y. Choi; C. Cudalbu; R. A. de Graaf et al. 

Nmr In Biomedicine. 2020-08-17.  p. e4347. DOI : 10.1002/nbm.4347.

Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease

V. Rackayova; O. Braissant; A-L. Rougemont; C. Cudalbu; V. A. McLin 

Scientific Reports. 2020. Vol. 10, num. 1, p. 7536. DOI : 10.1038/s41598-020-64416-3.

MP-PCA denoising dramatically improves SNR in large-sized MRS data: an illustration in diffusion-weighted MRS

I. Jelescu; J. Veraart; C. R. Cudalbu 

ISMRM 28th Annual Meeting & Exhibition, Paris, France, August 8-13, 2020.

Probiotics Combined With Rifaximin for the Treatment of Chronic Hepatic Encephalopathy: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism Using BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; P. Mastromarino et al. 

2019-09-01. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S19-S19. DOI : 10.14309/01.ajg.0000582124.67482.93.

Brain Regional Susceptibility to Oxidative Stress in a Rat Model of Chronic Hepatic Encephalopathy: In-Vivo 1H MRS, Ex-Vivo ESR Spectroscopy and Histology Findings

K. Pierzchala; D. Simicic; V. Rackayova; D. Sessa; A. Sienkiewicz et al. 

2019-09-01. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S33-S36. DOI : 10.14309/01.ajg.0000582248.03815.eb.

Antibiotic Rifaximin for Treatment of Chronic Liver Disease-Induced HE: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism on BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; R. Gruetter et al. 

2019-09-01. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S18-S19. DOI : 10.14309/01.ajg.0000582120.59858.08.

In Vivo Longitudinal 1H MRS Study of Hippocampal, Cereberal and Striatal Metabolic Changes in the Adult Brain Using an Animal Model of Chronic Hepatic Encephalopathy

D. Simicic; K. Pierzchala; V. Rackayova; O. Braissant; S-O. Mitrea et al. 

2019-09-01. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S17-S17. DOI : 10.14309/01.ajg.0000582108.29364.13.

Cholestasis Decreases Dendritic Spine Density in a Rat Hippocampal Organotypic Culture

L. Giovannoni; M. De Roo; O. Braissant; H. Henry; C. Cudalbu et al. 

2019-09-01. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S37-S38. DOI : 10.14309/01.ajg.0000582272.41932.fe.

Hippocampal and Cerebellar Astrocytes Morphological Alterations in a Rat Model of Chronic Hepatic Encephalopathy

K. Pierzchala; D. Simicic; O. Braissant; V. A. McLin; C. Cudalbu 

2019-09-01. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S33-S33.

Neurometabolism in Grey Matter of Children With Chronic Liver Disease or Portosystemic Shunting: A 1H-MRS Study at 7T

C. Cudalbu; L. Xin; S. Lachat; N. Valenza; F. Zangas-Gehri et al. 

2019-09-01. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S31-S32. DOI : 10.14309/01.ajg.0000582224.88567.2a.

Reply to: “Magnetic resonance spectroscopy: A surrogate marker of hepatic encephalopathy?”

V. A. Mclin; O. Braissant; C. Cudalbu 

Journal of Hepatology. 2019-11-01. Vol. 71, num. 5, p. 1057-1057. DOI : 10.1016/j.jhep.2019.08.003.

Bile Acids And Ammonium Contribute To Changes In Dendritic Spine Distribution In An Organotypic Culture Of Rat Hippocampus

L. Giovannoni; M. Deroo; O. Braissant; H. Henry; C. R. Cudalbu et al. 

2019-10-01. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Boston, MA, Nov 08-12, 2019. p. 471A-472A.

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

O. Braissant; V. Rackayova; K. Pierzchala; J. Grosse; V. A. McLin et al. 

Journal Of Hepatology. 2019-09-01. Vol. 71, num. 3, p. 505-515. DOI : 10.1016/j.jhep.2019.05.022.

Brain Edema in Chronic Hepatic Encephalopathy

C. Cudalbu; S. D. Taylor-Robinson 

Journal Of Clinical And Experimental Hepatology. 2019-05-01. Vol. 9, num. 3, p. 362-382. DOI : 10.1016/j.jceh.2019.02.003.

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M. Wilson; O. Andronesi; P. B. Barker; R. Bartha; A. Bizzi et al. 

Magnetic Resonance in Medicine. 2019. Vol. 82, num. 2, p. 527-550. DOI : 10.1002/mrm.27742.

Metabolic And Transcriptional Profiles Of Gbm Invasion: Comparison Of Patients And Paired Patient Derived Xenografts Using1H Magnetic Resonance Spectroscopy And Imaging (7T And 14T) And Rna-Sequencing

M. Hegi; C. Cudalbu; P. Bady; M. Lai; L. Xin et al. 

2018-11-01. 23rd Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd CNS Anticancer Drug Discovery and Development Conference, New Orleans, LA, Nov 14-18, 2018. p. 35-35.

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

H. A. I. Yoshihara; D. Firsov; C. R. Cudalbu; R. Gruetter 

ISMRM 2018, Paris, France, June16-21, 2018.

Brain metabolism during Chronic Hepatic Encephalopathy studied by in vivo 1H and 31P MRS

V. Rackayová / R. Gruetter; C. R. Cudalbu (Dir.)  

Lausanne, EPFL, 2018. 

In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

M. Lai; I. Vassallo; B. Lanz; C. Poitry-Yamate; M-F. Hamou et al. 

International Journal of Cancer. 2018. Vol. 143, num. 1, p. 127-138. DOI : 10.1002/ijc.31299.

In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

M. Lai; B. Lanz; C. Poitry-Yamate; J. F. Romero; C. M. Berset et al. 

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2018. Vol. 38, num. 10, p. 1701-1714. DOI : 10.1177/0271678X17734101.

Editorial for the special issue on introduction to in vivo Magnetic Resonance Spectroscopy (MRS): A method to non-invasively study metabolism

C. Cudalbu; A. J. L. Cooper 

Analytical Biochemistry. 2017. Vol. 529, p. 1-3. DOI : 10.1016/j.ab.2017.05.014.

Metabolic changes in developing brain due to chronic liver disease: an in vivo longitudinal and multiparametric study using P-31-MRS (magnetic resonance spectroscopy), P-31-Magnetization transfer and H-1-MRS

V. Rackayova; V. Mlynarik; C. Cudalbu 

2017. 28th International Symposium on Cerebral Blood Flow, Metabolism and Function / 13th International Conference on Quantification of Brain Function with PET, Int Soc Cerebral Blood Flow & Metab, Berlin, GERMANY, APR 01-04, 2017. p. 496-497.

MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models

B. Lanz; V. Rackayova; O. Braissant; C. Cudalbu 

Analytical biochemistry. 2017. Vol. 529, p. 245-269. DOI : 10.1016/j.ab.2016.11.021.

Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies

V. Rackayova; C. Cudalbu; P. J. W. Pouwels; O. Braissant 

Analytical biochemistry. 2017. Vol. 529, p. 144-157. DOI : 10.1016/j.ab.2016.11.007.

Brain edema: a valid endpoint for measuring hepatic encephalopathy?

C. Bémeur; C. Cudalbu; G. Dam; A. S. Thrane; A. J. L. Cooper et al. 

Metabolic brain disease. 2016. Vol. 31, num. 6, p. 1249-1258. DOI : 10.1007/s11011-016-9843-9.

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

V. Rackayova; O. Braissant; V. A. McLin; C. Berset; B. Lanz et al. 

Metabolic brain disease. 2016. Vol. 31, num. 6, p. 1303-1314. DOI : 10.1007/s11011-015-9715-8.

In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T

C. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al. 

Neurochemical research. 2015. Vol. 40, num. 12, p. 2639-2646. DOI : 10.1007/s11064-015-1643-9.

Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T

M. Lai; C. R. Cudalbu; B. Lanz; I. Vassallo; M-F. Hamou et al. 

2014. International Society for Magnetic Resonance in Medicine, Milan, May 10-16, 2014.

In vivo 13C MRS in the mouse brain at 14.1 T and metabolic flux quantification during infusion of [1,6-13C2] Glucose

M. Lai; B. Lanz; C. J. d. C. Romero; C. R. Cudalbu; R. Gruetter 

2014. International Society for Magnetic Resonance in Medicine, Milan, May 10-16, 2014.

Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

M. Craveiro; C. Cudalbu; V. Mlynárik; R. Gruetter 

NMR in Biomedicine. 2014. Vol. 27, num. 10, p. 1151-1158. DOI : 10.1002/nbm.3168.

Studying glioblastoma progression in a rat model of human glioma initiating cells using 1H MRS and DTI

M. Mishkovsky; C. R. Cudalbu; E. Can; D. Mario; I. Radovanovic et al. 

2014. International Society for Magnetic Resonance in Medicine, Milano, Italy, 2014.

Clinical Proton MR Spectroscopy in Central Nervous System Disorders

G. Öz; J. R. Alger; P. B. Barker; R. Bartha; A. Bizzi et al. 

Radiology. 2014. Vol. 270, num. 3, p. 658-679. DOI : 10.1148/radiol.13130531.

In vivo brain macromolecule signals in healthy and glioblastoma mouse models: 1H magnetic resonance spectroscopy, post-processing and metabolite quantification at 14.1 T

M. Craveiro; V. Clément-Schatlo; D. Marino; R. Gruetter; C. Cudalbu 

Journal of Neurochemistry. 2014. Vol. 129, num. 5, p. 806-815. DOI : 10.1111/jnc.12673.

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

2013. 64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases. p. 803A-803A.

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. Mclin 

2013. 64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases’, u’64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases’. p. 393A-393A.

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. McLin 

2013. The 64th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2013, Washington, DC, November 1 – 5, 2013. p. 379.

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

2013. The 64th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2013, Washington, DC, November 1 – 5, 2013. p. 1219.

The C57BL/6J Mouse Exhibits Sporadic Congenital Portosystemic Shunts

C. Cudalbu; V. A. Mclin; H. Lei; J. M. N. Duarte; A-L. Rougemont et al. 

PLoS ONE. 2013. Vol. 8, num. 7, p. e69782. DOI : 10.1371/journal.pone.0069782.

Brain metabolism in rat model of human glioma initiating cells

M. Mishkovsky; C. R. Cudalbu; A. Comment; D. Mario; I. Radovanovic et al. 

2013. International Society for Magnetic Resonance in Medicine, Salt Lake City, USA, April 2013.

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. R. Cudalbu; V. McLin; H. Lei; J. das Neves Duarte; A-L. Rougemont et al. 

ISMRM.

In vivo and longitudinal assessment of brain metabolism in Hepatic Encephalopathy using 1H MRS

C. R. Cudalbu; V. McLin; O. Braissant; R. Gruetter 

ISMRM.

Hepatic encephalopathy and brain metabolism: a longitudinal in vivo study

C. Cudalbu; V. McLin; O. Braissant 

2013. 24th Biennial Meeting of the International-Society-for-Neurochemistry and the American-Society-for-Neurochemistry, Cancun, MEXICO, APR 20-24, 2013. p. 178-179.

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. Cudalbu; V. McLin; H. Lei; J. Duarte; A. Rougemont et al. 

2013. 24th Biennial Meeting of the International-Society-for-Neurochemistry and the American-Society-for-Neurochemistry, Cancun, MEXICO, APR 20-24, 2013. p. 107-108.

In vivo studies of brain metabolism in animal models of Hepatic Encephalopathy using (1)H Magnetic Resonance Spectroscopy

C. Cudalbu 

Metabolic brain disease. 2013. Vol. 28, num. 2, p. 167-174. DOI : 10.1007/s11011-012-9368-9.

Ammonia toxicity to the brain

O. Braissant; V. A. McLin; C. Cudalbu 

Journal of inherited metabolic disease. 2013. Vol. 36, num. 4, p. 595-612. DOI : 10.1007/s10545-012-9546-2.

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

L. Xin; G. Gambarota; C. Cudalbu; V. Mlynárik; R. Gruetter 

Magma (New York, N.Y.). 2013. Vol. 26, num. 6, p. 549-554. DOI : 10.1007/s10334-013-0378-3.

Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

B. Schaller; L. Xin; C. Cudalbu; R. Gruetter 

NMR in biomedicine. 2013. Vol. 26, num. 5, p. 593-599. DOI : 10.1002/nbm.2896.

Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARES

B. Lanz; J. M. N. Duarte; N. Kunz; V. Mlynárik; R. Gruetter et al. 

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2013. Vol. 69, num. 6, p. 1512-1522. DOI : 10.1002/mrm.24406.

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. Van de Looij et al. 

ISMRM 20th Annual Scientific Meeting, 5-11 May 2012, Melbourne, Australia.

Brain osmolytes and brain edema in a rat model of chronic liver failure: in vivo longitudinal 1H Spectroscopic imaging and Diffusion tensor imaging studies at 9.4T

C. R. Cudalbu; O. Braissant; M. Lepore; R. Gruetter; V. McLin 

The 15th International Society of Hepatic Encephalopathy and Nitrogen Metabolism, Symposium May 29 – June 2, 2012, Denmark.

Handling macromolecule signals in the quantification of the neurochemical profile

C. Cudalbu; V. Mlynárik; R. Gruetter 

Journal of Alzheimer’s disease : JAD. 2012. Vol. 31, p. S101-15. DOI : 10.3233/JAD-2012-120100.

Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer’s disease

V. Mlynárik; M. Cacquevel; L. Sun-Reimer; S. Janssens; C. Cudalbu et al. 

Journal of Alzheimer’s disease : JAD. 2012. Vol. 31, p. S87-99. DOI : 10.3233/JAD-2012-112072.

Phosphorus MRS Study of a Murine Model of Peripheral Arterial Disease

V. Mlynárik; M. Pellegrin; C. R. Cudalbu; L. Mazzolai; R. Gruetter 

2012. ISMRM 20th Annual Scientific Meeting, Melbourne, Australia, 5-11 May 2012.

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. van de Looij et al. 

2012. ISMRM 20th Annual Scientific Meeting, Melbourne, Australia, 5-11 May 2012.

Assessment Of Cerebral Osmotic Regulation In A Rat Model Of Biliary Cirrhosis Using MR Spectroscopy

V. A. McLin; O. Braissant; Y. van de Looij; N. Kunz; R. Gruetter et al. 

2012. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona, SPAIN, Apr 18-22, 2012. p. S231-S232.

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy

C. R. Cudalbu; B. Lanz; J. M. N. Duarte; F. D. Morgenthaler; Y. Pilloud et al. 

Journal Of Cerebral Blood Flow And Metabolism. 2012. Vol. 32, p. 696-708. DOI : 10.1038/jcbfm.2011.173.

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Mlynarik; C. R. Cudalbu; V. Clement; D. Marino; I. Radovanovic et al. 

Nmr In Biomedicine. 2012. Vol. 25, p. 506-513. DOI : 10.1002/nbm.1763.

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Clement-Schatlo; V. Mlynarik; C. Cudalbu; D. Marino; I. Radovanovic et al. 

2011.  p. S15-S15.