PUBLICATIONS

Rescue of myocytes and locomotion through AAV2/9-2YF intracisternal gene therapy in a rat model of creatine transporter deficiency

G. Fernandes-Pires; M. D. Azevedo; M. Lanzillo; C. Roux-Petronelli; P-A. Binz et al. 

Diffusion of brain metabolites highlights altered brain microstructure in type C hepatic encephalopathy: a 9.4 T preliminary study

J. Mosso; G. Briand; K. Pierzchala; D. Simicic; A. Sierra et al. 

Inhibition of urease-mediated ammonia production by 2-octynohydroxamic acid in hepatic encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

Diffusion-weighted SPECIAL improves the detection of J-coupled metabolites at ultrahigh magnetic field

J. Mosso; D. Simicic; B. Lanz; R. Gruetter; C. Cudalbu 

New Insights Into Brain Energy Metabolism in Type C Hepatic Encephalopathy: A Dual ¹⁸F-FDG PET and 9.4T ¹H MRS Preclinical Study

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Automated segmentation and labeling of subcutaneous mouse implants at 14.1T

J. Adda; G. Bioley; D. van de Ville; C. Cudalbu; M. G. Preti et al. 

Neurometabolic profiles of bile duct ligated rats after the treatment with an urease inhibitor – 1H MRS dataset

D. Evstafeva; J-C. Leroux; C. R. Cudalbu; D. Simicic 

Diffusion-weighted MR spectroscopy: Consensus, recommendations, and resources from acquisition to modeling

C. Ligneul; C. Najac; A. Doring; C. Beaulieu; F. Branzoli et al. 

Evaluation of a Hydroxamate-Based Urease Inhibitor in a Rodent Model of Hepatic Encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

Brain Regional Differences in the Developing Brain Using an Animal Model of Type C Hepatic Encephalopathy

D. Simicic; K. Pierzchala; O. Braissant; C. Toso; G. Oldani et al. 

Age Dependence of Neurometabolic Changes in a Rat Pup Model of Type C Hepatic Encephalopathy

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

The Beneficial Effect of Oral Cr Supplementation in an Early Childhood Rat Model of Chronic Hepatic Encephalopathy: In Vivo Longitudinal ¹H and ³¹P Magnetic Resonance Spectroscopy Study

D. Simicic; O. Braissant; K. Pierzchala; S. Mitrea; D. Sessa et al. 

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Lessons on brain edema in HE: from cellular to animal models and clinical studies

K. Pierzchala; A. Hadjihambi; J. Mosso; R. Jalan; C. F. F. Rose et al. 

Editorial for the special issue on Brain Biochemistry in Liver Disease

C. Cudalbu; A. J. L. Cooper 

High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study

C. Cudalbu; L. Xin; B. Marechal; S. Lachat; F. Zangas-Gheri et al. 

Central Nervous System Oxidative Stress interplay with inflammation in a rat model of Type C Hepatic Encephalopathy – brothers in arms?

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Neurometabolic changes in a rat pup model of type C hepatic encephalopathy depend on age at liver disease onset

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

Harmonization of multi-scanner in vivo magnetic resonance spectroscopy: ENIGMA consortium task group considerations

A. D. Harris; H. Amiri; M. Bento; R. Cohen; C. R. K. Ching et al. 

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy (vol 178, pg 295, 2022)

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

MP-PCA denoising for diffusion MRS data: promises and pitfalls

J. Mosso; D. Simicic; K. Simsek; R. Kreis; C. Cudalbu et al. 

Overview of oxidative stress findings in hepatic encephalopathy: From cellular and ammonium-based animal models to human data

D. Simicic; C. Cudalbu; K. Pierzchala 

Central Nervous System Oxidative Stress Interplay With Inflammation In A Rat Model Of Type C Hepatic Encephalopathy – Brothers In Arms?

P. Katarzyna; S. Dunja; S. Dario; M. Stefanita; B. Olivier et al. 

Advanced metabolite mapping at ultra-high field using 1H-MRS, 1H-MRSI and macromolecules: applications in a rat model of type C hepatic encephalopathy

Abnormal brain oxygen homeostasis in an animal model of liver disease

A. Hadjihambi; C. Cudalbu; K. Pierzchala; D. Simicic; C. Donnelly et al. 

PET CMRglc mapping and H-1-MRS show altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Quantitative FDG-PET and 1H-MRS reveal altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy

L. Duran-Trio; G. Fernandes-Pires; J. Grosse; I. Soro-Arnaiz; C. Roux-Petronelli et al. 

Probiotics combined with rifaximin influence the neurometabolic changes in a rat model of type C HE

E. Flatt; V. A. McLin; O. Braissant; K. Pierzchala; P. Mastromarino et al. 

Hyperpolarized C-13-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

M. Mishkovsky; O. Gusyatiner; B. Lanz; C. Cudalbu; I. Vassallo et al. 

Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease

V. Rackayova; E. Flatt; O. Braissant; J. Grosse; D. Capobianco et al. 

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

C. Cudalbu; P. Bady; M. Lai; L. Xin; O. Gusyatiner et al. 

In vivo macromolecule signals in rat brain 1 H‐MR spectra at 9.4T: Parametrization, spline baseline estimation, and T 2 relaxation times

D. Simicic; V. Rackayová; L. Xin; I. Tkáč; T. Borbath et al. 

The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery

M. G. Melo; N. Remacle; H-P. Cudre-Cung; C. Roux; M. Poms et al. 

2021 ISHEN guidelines on animal models of hepatic encephalopathy

S. DeMorrow; C. Cudalbu; N. Davies; A. R. Jayakumar; C. F. Rose 

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts’ consensus recommendations

A. Lin; O. Andronesi; W. Bogner; I-Y. Choi; E. Coello et al. 

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

L. Duran-Trio; G. Fernandes-Pires; D. Simicic; J. Grosse; C. Roux-Petronelli et al. 

Late post‐natal neurometabolic development in healthy male rats using 1 H and 31 P Magnetic Resonance Spectroscopy

V. Račkayová; D. Simicic; G. Donati; O. Braissant; R. Gruetter et al. 

Contribution of macromolecules to brain H-1 MR spectra: Experts’ consensus recommendations

C. Cudalbu; K. L. Behar; P. K. Bhattacharyya; W. Bogner; T. Borbath et al. 

Magnetic resonance spectroscopy in the rodent brain: Experts’ consensus recommendations

B. Lanz; A. Abaei; O. Braissant; I-Y. Choi; C. Cudalbu et al. 

B(0)shimming for in vivo magnetic resonance spectroscopy: Experts’ consensus recommendations

C. Juchem; C. Cudalbu; R. A. de Graaf; R. Gruetter; A. Henning et al. 

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts’ consensus recommendations

R. Kreis; V. Boer; I-Y. Choi; C. Cudalbu; R. A. de Graaf et al. 

Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease

V. Rackayova; O. Braissant; A-L. Rougemont; C. Cudalbu; V. A. McLin 

MP-PCA denoising dramatically improves SNR in large-sized MRS data: an illustration in diffusion-weighted MRS

I. Jelescu; J. Veraart; C. R. Cudalbu 

Probiotics Combined With Rifaximin for the Treatment of Chronic Hepatic Encephalopathy: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism Using BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; P. Mastromarino et al. 

Brain Regional Susceptibility to Oxidative Stress in a Rat Model of Chronic Hepatic Encephalopathy: In-Vivo 1H MRS, Ex-Vivo ESR Spectroscopy and Histology Findings

K. Pierzchala; D. Simicic; V. Rackayova; D. Sessa; A. Sienkiewicz et al. 

Antibiotic Rifaximin for Treatment of Chronic Liver Disease-Induced HE: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism on BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; R. Gruetter et al. 

In Vivo Longitudinal 1H MRS Study of Hippocampal, Cereberal and Striatal Metabolic Changes in the Adult Brain Using an Animal Model of Chronic Hepatic Encephalopathy

D. Simicic; K. Pierzchala; V. Rackayova; O. Braissant; S-O. Mitrea et al. 

Cholestasis Decreases Dendritic Spine Density in a Rat Hippocampal Organotypic Culture

L. Giovannoni; M. De Roo; O. Braissant; H. Henry; C. Cudalbu et al. 

Hippocampal and Cerebellar Astrocytes Morphological Alterations in a Rat Model of Chronic Hepatic Encephalopathy

K. Pierzchala; D. Simicic; O. Braissant; V. A. McLin; C. Cudalbu 

Neurometabolism in Grey Matter of Children With Chronic Liver Disease or Portosystemic Shunting: A 1H-MRS Study at 7T

C. Cudalbu; L. Xin; S. Lachat; N. Valenza; F. Zangas-Gehri et al. 

Reply to: “Magnetic resonance spectroscopy: A surrogate marker of hepatic encephalopathy?”

V. A. Mclin; O. Braissant; C. Cudalbu 

Bile Acids And Ammonium Contribute To Changes In Dendritic Spine Distribution In An Organotypic Culture Of Rat Hippocampus

L. Giovannoni; M. Deroo; O. Braissant; H. Henry; C. R. Cudalbu et al. 

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

O. Braissant; V. Rackayova; K. Pierzchala; J. Grosse; V. A. McLin et al. 

Brain Edema in Chronic Hepatic Encephalopathy

C. Cudalbu; S. D. Taylor-Robinson 

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M. Wilson; O. Andronesi; P. B. Barker; R. Bartha; A. Bizzi et al. 

Metabolic And Transcriptional Profiles Of Gbm Invasion: Comparison Of Patients And Paired Patient Derived Xenografts Using1H Magnetic Resonance Spectroscopy And Imaging (7T And 14T) And Rna-Sequencing

M. Hegi; C. Cudalbu; P. Bady; M. Lai; L. Xin et al. 

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

H. A. I. Yoshihara; D. Firsov; C. R. Cudalbu; R. Gruetter 

Brain metabolism during Chronic Hepatic Encephalopathy studied by in vivo 1H and 31P MRS

In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

M. Lai; I. Vassallo; B. Lanz; C. Poitry-Yamate; M-F. Hamou et al. 

In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

M. Lai; B. Lanz; C. Poitry-Yamate; J. F. Romero; C. M. Berset et al. 

Editorial for the special issue on introduction to in vivo Magnetic Resonance Spectroscopy (MRS): A method to non-invasively study metabolism

C. Cudalbu; A. J. L. Cooper 

Metabolic changes in developing brain due to chronic liver disease: an in vivo longitudinal and multiparametric study using P-31-MRS (magnetic resonance spectroscopy), P-31-Magnetization transfer and H-1-MRS

V. Rackayova; V. Mlynarik; C. Cudalbu 

MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models

B. Lanz; V. Rackayova; O. Braissant; C. Cudalbu 

Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies

V. Rackayova; C. Cudalbu; P. J. W. Pouwels; O. Braissant 

Brain edema: a valid endpoint for measuring hepatic encephalopathy?

C. Bémeur; C. Cudalbu; G. Dam; A. S. Thrane; A. J. L. Cooper et al. 

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

V. Rackayova; O. Braissant; V. A. McLin; C. Berset; B. Lanz et al. 

In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T

C. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al. 

Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T

M. Lai; C. R. Cudalbu; B. Lanz; I. Vassallo; M-F. Hamou et al. 

In vivo 13C MRS in the mouse brain at 14.1 T and metabolic flux quantification during infusion of [1,6-13C2] Glucose

M. Lai; B. Lanz; C. J. d. C. Romero; C. R. Cudalbu; R. Gruetter 

Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

M. Craveiro; C. Cudalbu; V. Mlynárik; R. Gruetter 

Studying glioblastoma progression in a rat model of human glioma initiating cells using 1H MRS and DTI

M. Mishkovsky; C. R. Cudalbu; E. Can; D. Mario; I. Radovanovic et al. 

Clinical Proton MR Spectroscopy in Central Nervous System Disorders

G. Öz; J. R. Alger; P. B. Barker; R. Bartha; A. Bizzi et al. 

In vivo brain macromolecule signals in healthy and glioblastoma mouse models: 1H magnetic resonance spectroscopy, post-processing and metabolite quantification at 14.1 T

M. Craveiro; V. Clément-Schatlo; D. Marino; R. Gruetter; C. Cudalbu 

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. Mclin 

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. McLin 

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

The C57BL/6J Mouse Exhibits Sporadic Congenital Portosystemic Shunts

C. Cudalbu; V. A. Mclin; H. Lei; J. M. N. Duarte; A-L. Rougemont et al. 

Brain metabolism in rat model of human glioma initiating cells

M. Mishkovsky; C. R. Cudalbu; A. Comment; D. Mario; I. Radovanovic et al. 

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. R. Cudalbu; V. McLin; H. Lei; J. das Neves Duarte; A-L. Rougemont et al. 

In vivo and longitudinal assessment of brain metabolism in Hepatic Encephalopathy using 1H MRS

C. R. Cudalbu; V. McLin; O. Braissant; R. Gruetter 

Hepatic encephalopathy and brain metabolism: a longitudinal in vivo study

C. Cudalbu; V. McLin; O. Braissant 

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. Cudalbu; V. McLin; H. Lei; J. Duarte; A. Rougemont et al. 

In vivo studies of brain metabolism in animal models of Hepatic Encephalopathy using (1)H Magnetic Resonance Spectroscopy

C. Cudalbu 

Ammonia toxicity to the brain

O. Braissant; V. A. McLin; C. Cudalbu 

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

L. Xin; G. Gambarota; C. Cudalbu; V. Mlynárik; R. Gruetter 

Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

B. Schaller; L. Xin; C. Cudalbu; R. Gruetter 

Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARES

B. Lanz; J. M. N. Duarte; N. Kunz; V. Mlynárik; R. Gruetter et al. 

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. Van de Looij et al. 

Brain osmolytes and brain edema in a rat model of chronic liver failure: in vivo longitudinal 1H Spectroscopic imaging and Diffusion tensor imaging studies at 9.4T

C. R. Cudalbu; O. Braissant; M. Lepore; R. Gruetter; V. McLin 

Handling macromolecule signals in the quantification of the neurochemical profile

C. Cudalbu; V. Mlynárik; R. Gruetter 

Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer’s disease

V. Mlynárik; M. Cacquevel; L. Sun-Reimer; S. Janssens; C. Cudalbu et al. 

Phosphorus MRS Study of a Murine Model of Peripheral Arterial Disease

V. Mlynárik; M. Pellegrin; C. R. Cudalbu; L. Mazzolai; R. Gruetter 

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. van de Looij et al. 

Assessment Of Cerebral Osmotic Regulation In A Rat Model Of Biliary Cirrhosis Using MR Spectroscopy

V. A. McLin; O. Braissant; Y. van de Looij; N. Kunz; R. Gruetter et al. 

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy

C. R. Cudalbu; B. Lanz; J. M. N. Duarte; F. D. Morgenthaler; Y. Pilloud et al. 

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Mlynarik; C. R. Cudalbu; V. Clement; D. Marino; I. Radovanovic et al. 

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Clement-Schatlo; V. Mlynarik; C. Cudalbu; D. Marino; I. Radovanovic et al.