Publications

Link to our full publication list on PubMed.

 

2024

Tollenaere A, Ugur E, Deluz C, Leonhardt H, Suter DM. Mechanistic basis of gene regulation by SRCAP and H2A.Z

bioRxiv

Shaban HA, Friman ET, Deluz C, Tollenaere A, Katanayeva N, Suter DM. Individual transcription factors modulate both the micromovement of chromatin and its long-range structure

PNAS

Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM. Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets

Nature Communications

2023

Martin B, Suter DM. Gene expression flux analysis reveals specific regulatory modalities of gene expression

iScience

Placzek S, Vanzan L, Suter DM. Orchestration of pluripotent stem cell genome reactivation during mitotic exit

bioRxiv

Martin B, Suter DM. An out-of-equilibrium definition of protein turnover

BioEssays

2022

Shaban HA, Suter DM.  Individual activator and repressor transcription factors induce global changes in chromatin mobility

bioRxiv

2020

Suter DM. Transcription Factors and DNA Play Hide and Seek Corresponding author.

Trends in Cell Biology

2019

Friman ET, Deluz C, Meireles-Filho A, Govindan A, Gardeux V, Deplancke B, Suter DM. Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle.Corresponding author

eLife

Tidin O, Friman ET, Naef F, Suter DM. Quantitative relationships between SMAD dynamics and target gene activation kinetics in single live cells. Equal contribution and co-corresponding authors

Scientific Reports

Alber AB, Suter DM. Dynamics of Protein Synthesis and Degradation through the Cell Cycle.

Cell Cycle

Strebinger D*, Deluz C*, Friman ET*, Govindan S, Alber AB, Suter DM. Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions. *Equal contribution; Corresponding author

Molecular Systems Biology

Phillips NE*, Mandic A*, Omidi S, Naef F, Suter DM. Memory and relatedness of transcriptional activity in mammalian cell lineages. *Equal contribution; Equal contribution and Corresponding authors

Nature Communications

Raccaud M, Alber AB, Friman ET, Agarwal H, Deluz C, Kuhn T, Gebhardt JCM, Suter DM.Mitotic chromosome binding predicts transcription factor properties in interphase. Corresponding author

Nature Communications

Callegari A, Sieben C, Benke A, Suter DM, Fierz B, Mazza D, Manley SSingle-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation.

PLoS Genetics

2018

Alber AB*, Paquet ER*, Biserni M, Naef F, Suter DM. Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates

Molecular Cell

Link to Alber et al.

Nicolas D, Zoller B, Suter DM, Naef F. Modulation of transcriptional burst frequency by histone acetylation.

PNAS

Alber AB, Suter DM. Single-Cell Quantification of Protein Degradation Rates by Time-Lapse Fluorescence Microscopy in Adherent Cell Culture.

Journal of Visualized Experiments.

2017

Delachat AM, Guidotti N, Bachmann AL, Meireles-Filho ACA, Pick H, Lechner CC, Deluz C, Deplancke B, Suter DM, Fierz B. Engineered Multivalent Sensors to Detect Coexisting Histone Modifications in Living Stem Cells.

Cell Chemical Biology

Raccaud M, Suter DM. Transcription factor retention on mitotic chromosomes: regulatory mechanisms and impact on cell fate decisions.

FEBS letters

Mandic A, Strebinger D, Regali C, Phillips NE, Suter DM. A novel method for quantitative measurements of gene expression in single living cells

Methods  Link to PDF
 
Deluz C, Strebinger D, Friman ET, Suter DM. The elusive role of mitotic bookmarking in transcriptional regulation: insights from Sox2.
Cell Cycle  Link to PDF

2016

Deluz C, Friman ET, Strebinger D, Benke A, Raccaud M, Callegari A, Leleu M, Manley S, Suter DM. A role for mitotic bookmarking of SOX2 in pluripotency and differentiation.          
Genes & Development  Link to PDF

2014

Zhao ZW*, Roy R*, Gebhardt JCM*, Suter DM*, Chapman A, Xie XS. Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy. *Equal contribution
PNAS

2013

Molina N*, Suter DM*†, Zoller B, Gotic I, Naef F†. Stimulus-induced modulation of transcriptional bursting in a single mammalian gene. *Equal contribution; †Corresponding authors
PNAS

Zhao ZW, Gebhardt JC, Suter DM, Xie XS. Reply to “Convergence of chromatin binding estimates in live cells”.
Nature Methods

Gebhardt JCM* Suter DM*, Roy R, Zhao ZW, Chapman A, Basu S, Maniatis T, Xie XS. Probing Transcription Factor DNA Binding at the Single Molecule Level in Live Mammalian Cells. *Equal contribution.
Nature Methods 2013 repository/default/content/sites/suter-lab/files/Gebhardt, Suter et al.pdf

2012

Kern I, Xu R, Julien S, Suter DM, Preynat-Seauve O, Baquié M, Poncet A, Combescure C, Stoppini L, van Thriel C, Krause KH. Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells.
Current Medicinal Chemistry

Stratmann M*, Suter DM*, Molina N, Naef F, Schibler U. Circadian Dbp Transcription Relies on Highly Dynamic BMAL1-CLOCK Interaction with E Boxes and Requires the Proteasome. *Equal contribution.
Molecular Cell

2011

Suter DM, Molina N, Naef F, Schibler U. Origins and consequences of transcriptional discontinuity.
Current Opinion in Cell Biology

Link to full text

Saini C, Suter DM, Liani A, Gos P, Schibler U. The Mammalian Circadian Timing System: Synchronization of Peripheral Clocks.
Cold Spring Harbor Symposia in Quantitative Biology. 2011

Clément S, Peyrou M, Sanchez-Pareja A, Bourgoin L, Ramadori P, Suter D, Vinciguerra M, Guilloux K, Pascarella S, Rubbia-Brandt L, Negro F, Foti M. Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets.
Hepatology

Suter DM*, Molina N*, Gatfield D, Schneider K, Schibler U, Naef F. Mammalian genes are transcribed with widely different bursting kinetics. *Equal contribution
Science

 

2010

Zhang J, Lu JP, Suter DM, Krause KH, Fini ME, Chen B, Lu Q. Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death.
Experimental Cell Research

 

2009

Suter DM, Schibler U. Physiology. Feeding the clock.
Science

Suter DM, Preynat-Seauve O, Tirefort D, Feki A, Krause KH. Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells.
Journal of Cellular and Molecular Medicine

Preynat-Seauve O, Suter DM, Tirefort D, Turchi L, Virolle T, Chneiweiss H, Foti M, Lobrinus JA, Stoppini L, Feki A, Dubois-Dauphin M, Krause KH. Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture.
Stem Cells

Suter DM, Tirefort D, Julien S, Krause KH. A Sox1 to Pax6 switch drives neuroectoderm to radial glia progression during differentiation of mouse embryonic stem cells.
Stem Cells

 

2008

Suter DM, Krause KH. Neural commitment of embryonic stem cells: molecules, pathways and potential for cell therapy.
Journal of Pathology

Link to full text

Aberdam E, Barak E, Rouleau M, de LaForest S, Berrih-Aknin S, Suter DM, Krause KH, Amit M, Itskovitz-Eldor J, Aberdam D. A pure population of ectodermal cells derived from human embryonic stem cells.
Stem Cells

 

2007

Suter DM, Montet X, Tirefort D, Cartier L, Krause KH. A tetracycline-inducible lentivector system based on EF1-α promoter and native tetracycline repressor allows in vivo gene induction in implanted ES cells.
Journal of Stem Cells

Radcliffe CM, Arnold JN, Suter DM, Wormald MR, Harvey DJ, Royle L, Mimura Y, Kimura Y, Sim RB, Inogès S, Rodriguez-Calvillo M, Zabalegui N, de Cerio AL, Potter KN, Mockridge CI, Dwek RA, Bendandi M, Rudd PM, Stevenson FK. Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
Journal of Biological Chemistry

Suter DM, Dubois-Dauphin M, Krause KH. Genetic engineering of embryonic stem cells.
Swiss Medical Weekly

 

2006

Suter DM, Cartier L, Bettiol E, Tirefort D, Jaconi ME, Dubois-Dauphin M, Krause KH. Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors.
Stem Cells

 

2005

Arnold JN, Wormald MR, Suter DM, Radcliffe CM, Harvey DJ, Dwek RA, Rudd PM, Sim RB. Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin.
Journal of Biological Chemistry