Understanding biological responses to toxic substances is important for pollution assessment and monitoring exposure to existing environmental contamination. Our research on linking effects across biological levels focuses on the toxic mechanisms at a molecular level and how these molecular changes relate to functional changes at the organism and population level. The approaches used are:
Systems biology
This is a biology-based inter-disciplinary study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective to study them. One of the goals of systems biology is to discover new emergent properties that may arise from the systemic view used by this discipline in order to understand better the entirety of processes that happen in a biological system. We analyze the response of a mouse cell line Hepa1c1c-7 upon exposure to Benzo(a) pyrene.
This project is closely related to the project Phenotypic anchoring.
