 Simulation Neuroscience Circuits |
Armando Romani is a Postdoctoral Fellow and Group Leader of the Circuits team within the Simulation Neuroscience Division.
Armando joined Blue Brain to work on a biophysically detailed model of the hippocampus. The hippocampus plays a key role in memory formation, spatial navigation, and other fundamental cognitive functions. Before moving to Blue Brain, Armando spent two years as a collaborator at the Laboratory of Computational Embodied Neuroscience, group leader Dr. Gianluca Baldassarre, Institute of Cognitive Sciences and Technologies, National Research Council (Rome, Italy). Prior to that, he was a PhD student at the ‘Molecular Mechanisms of Synaptic Plasticity’ laboratory, group leader Dr. Hélène Marie, European Brain Research Institute, Rita Levi-Montalcini Foundation (Rome, Italy). Armando has a degree in Biology from the University ‘Roma Tre’, Italy and a PhD in Neuroscience from the University ‘Tor Vergata’, Rome, Italy. A competitive chess player who plays in national and international competitions, he also enjoys outdoor sports including running, swimming and hiking.
Selected Publications Sáray S, Rössert CA, Appukuttan S, Migliore R, Vitale P, Lupascu CA, Bologna LL, Van Geit W, Romani A et al. (2021) HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data. PLoS Comput Biol. 17(1):e1008114. Ecker A, Romani A et al. (2020) Data-driven integration of hippocampal CA1 synaptic physiology in silico. Hippocampus. 30(11):1129-1145. Migliore R, Lupascu CA, Bologna LL, Romani A, et al. (2018) The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow. PLoS Comput Biol. 14(9):e1006423. Romani A, Marchetti C, Bianchi D, Leinekugel X, Poirazi P, Migliore M, Marie H (2013) Computational modeling of the effects of amyloid-beta on release probability at hippocampal synapses. – Front Comput Neurosci. 7:1-7. The model is available on ModelDB (http://senselab.med.yale.edu/ModelDB/), accession number 147757. Houeland G, Romani A, Marchetti C, Amato G, Capsoni S, Cattaneo A, Marie H. (2010) Transgenic mice with chronic NGF deprivation and Alzheimer’s disease-like pathology display hippocampal region-specific impairments in short- and long-term plasticities. – J Neurosci. 30:13089-94. |
