For the majority of the following PhD thesis, having an important component of the technologies we provide, the PhD students were trained and supervised in our platform for their projects. Concretely, these students were educated, guided and supported in assay design, assay development, screening, data analysis, hits assignments and hits expansion. These projects aimed at investigating and understanding biological systems with bioactive molecules or probes detected using the designed assays and experiments.
2019
M. Bardyn, J.-D. Tissot (Dir.) – New routes in additive solution formulations to improve the quality of stored red blood cells. Université de Lausanne
V. Campos, O. Naveiras (Dir.) – Metabolic and microenvironmental strategies to accelerate hematopoietic recovery post-aplasia. EPFL, n° 9395
S. Haag, A. Ablasser (Dir.) – Identification and characterisation of small-molecule inhibitors targeting STING. EPFL, n° 9257
2018
A. Bazhin, E. Goun (Dir.) – Novel probes for the non-invasive bioluminescence imaging of mitochondrial membrane potential and dipeptidylpeptidase-4 activity in living animals. EPFL, n° 8061
A. Figuerola Conchas, M. Gotta (Dir.), R. Loewith (Dir.) – The AAA ATPase p97: from the use of genetics to the development of new chemical tools to study its functions. Université de Genève
2017
N. Brandenberg, M. Lutolf (Dir.) – Advanced technologies to control stem-cell based organogenesis. EPFL, n° 7461
2016
A. J. Lamontanara, O. Hantschel (Dir.) – Allosteric regulation and targeting of Abl SH2-kinase interface and other cytoplasmic tyrosine kinases. EPFL, n° 6987
A. Zaffalon, Y. Barrandon (Dir.) – Capturing epidermal stemness. EPFL, n° 6975
2015
C. Varenne, C. Heinis (Dir.), F. Radtke (Dir.) – Phage Selection of Bicyclic Peptides and High-Throughput Screening of Chemical Compounds for the Identification of Novel Inhibitors of the Notch Pathway. EPFL, n° 6635
2013
A. Ranga, M. Lutolf (Dir.) – Systems Biology of 3D Stem Cell-Niche Interactions. EPFL, n° 5685
P. Andreux, J. Auwerx (Dir.) – Identification of genetic determinants and pharmacological modulators of mitochondrial function. EPFL, n° 5795
2012
S. Kobel, M. Lutolf (Dir.), P. Renaud (Dir.) – Microtechnologies to Map the Fate of Single Stem Cells and their Progeny. EPFL, n° 5322
2011
R. Lehal, F. Radtke (Dir.) – Identification and Preclinical Validation of Inhibitors of the Notch Pathway. EPFL, n° 5254
2010
H. Ouertatani-Sakouhi, H. Lashuel (Dir.) – Small Molecule Based Approaches to Inhibit Macrophage Migration Inhibitory Factor (MIF) Activities and Elucidate its Role in Health and Disease. EPFL, n° 4633