Lentiviral vectors can effectively transduce a broad range of dividing and post-mitotic cells. Therefore, they are used for in vitro and in vivo gene delivery, including for the development of gene therapies.
For production of lentiviral vector particles, we use classical packaging techniques for vector pseudotyping with the vesicular stomatitis virus G protein (VSV-G) envelope.
Production of lentiviral vectors can be tailored for various in vitro applications. Vectors can also be produced at high titer for in vivo projects, in particular for CNS applications.