Chemical Biology Seminar Series 3 (CH-637) ‒ ISIC ‐ EPFL

The Chemical Biology Seminars Series is Organized by Prof. Christian Heinis, Prof. Beat Fierz and Prof. Angela Steinauer. It takes place every Tuesday at 16:15 unless otherwise indicated.

ChemBio Seminar by Dr. Takeshi Harayama (Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d’Azur, France)

Title: Connecting lipid tail structures to cellular functions Abstract: Cellular membranes are composed of a diverse set of lipids with tails that vary significantly in chain lengths, the number of double bonds and…

12-11-202412-11-2024

With: Dr. Takeshi Harayama
Place and room: MA A1 10
Category: Conferences – Seminars

Principles of Protein Assembly in Cells – CH637

19-11-202419-11-2024

With: Prof Emmanuel Levy
Place and room: BCH 1113
Category: Conferences – Seminars

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Past seminars

2024

Accelerating protein engineering with viral-based in vivo screening and evolution technologies – CH636

06-09-202406-09-2024

With: Prof. Bryan Dickinson
Place and room: BS 270
Category: Conferences – Seminars

Chemical Biology Seminar by Dr. Denisa Jamecna (Biochemie Zentrum Heidelberg / Osnabrück University, Germany)

28-05-202428-05-2024

Place and room: CO 120
Category: Conferences – Seminars

De novo lanthanide enzymes – from protein dynamics to photoredox catalysis +CH636

14-05-202414-05-2024

With: Cathleen Zeymer
Place and room: MED 0 1418
Category: Conferences – Seminars

From post-translational modification to drug discovery

25-04-202425-04-2024

With: Prof Edward Tate – Imperial Collegue of London
Place and room: CH G1 495
Category: Conferences – Seminars

A chemical biology toolbox for probing A-to-I RNA editing – CH636

16-04-202416-04-2024

With: Prof Jennifer Heemstra
Place and room: CE 1 105
Category: Conferences – Seminars

ChemBio Seminar by Prof. Maja Köhn (University of Freiburg, Germany)

05-03-202405-03-2024

Place and room: CH B3 30
Category: Conferences – Seminars

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2023

ChemBio seminar by Prof. Marco Di Antonio (Imperial College London, UK) – CH-635

28-11-202328-11-2023

With: Prof. Marco Di Antonio, Imperial College London, UK
Place and room: CE 1 1
Category: Conferences – Seminars

Machine learning based peptide design for diverse structures and functions

21-11-202321-11-2023

With: Prof. Dr. Gaurav Bhardwaj
Online: https://epfl.zoom.us/j/62430541332
Category: Conferences – Seminars

ChemBio Seminar by Prof. Randall Peterson (University of Utah)

10-11-202310-11-2023

With: Prof. Randall Peterson, College of Pharmacy, University of Utah, USA
Place and room: SV 1717
Category: Conferences – Seminars

ZOOM – ChemBio Seminar by Prof. Chang Liu (University of California, Irvine) – CH-635

07-11-202307-11-2023

With: Prof Chang Liu
Online: https://epfl.zoom.us/j/64520311798
Category: Conferences – Seminars

Making it stick: how to engineer selective covalent ligands for diverse applications in biology

24-10-202324-10-2023

With: Prof. Dr. Matt Bogyo, Stanford University
Place and room: CH G1 495
Category: Conferences – Seminars

ChemBio Seminar by Prof. Matt Shoulders (Massachusetts Institute of Technology Department of Chemistry) – CH-636

03-10-202303-10-2023

Place and room: CE 1 1
Category: Conferences – Seminars

Schläfli Prize 2023

28-09-202328-09-2023

With: Michelle Frei
Place and room: CO 3
Category: Conferences – Seminars

Chemical approaches to decoding histone epigenetics

26-09-202326-09-2023

With: Prof. David Li, University of Honkg Kong
Place and room: SV 1717
Category: Conferences – Seminars

Swiss Chemical Society (SCS) Lectureship – Prof. Scott Denmark (University of Illinois)

20-09-202320-09-2023

With: Prof. Scott Denmark, University of Illinois at Urbana-Champaign (UIUC), USA
Place and room: BCH 2201
Category: Conferences – Seminars

ChemBio Seminar by Prof. Michael Nash (Uni Basel/ETH Zurich): "Comprehensive Mutational Profiling of Cancer Therapeutic Enzymes by Proximity-Based Sequencing

19-09-202319-09-2023

With: Prof Michael Nash
Place and room: CE 1 4
Category: Conferences – Seminars

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2022

Illuminating the regulation of gene expression at the single‐molecule level

14-12-202214-12-2022

With: Prof. Sebastian Deindl (Uppsala University)
Place and room: CH G1 495
Category: Conferences – Seminars

Mechanism and functions of nascent chromatin assembly during DNA replication

13-12-202213-12-2022

With: Prof. Francesca Mattiroli (Hubrecht Institute)
Place and room: CH G1 495
Category: Conferences – Seminars

ChemBio seminar by Prof. Emily Balskus – CH-635

09-12-202209-12-2022

With: Prof. Emily Balskus
Place and room: CM 1 5
Category: Conferences – Seminars

Protein domain mimics as rationally designed modulators of biomolecular function

06-12-202206-12-2022

With: Prof. Dr. Paramjit Arora, New York University
Online: https://epfl.zoom.us/j/62430541332
Category: Conferences – Seminars

Organic Chemistry Seminar by Prof. Jakub Svenda – CH-635

30-11-202230-11-2022

With: Prof. Jakub Svenda Masaryk University, Czech Republic
Place and room: BCH 2201
Category: Conferences – Seminars

ChemBio e-seminar by Prof. Xiao Wang – CH-635

29-11-202229-11-2022

With: Prof. Xiao Wang Massachussetts Institute of Technology, USA
Online: https://epfl.zoom.us/j/65532538483
Category: Conferences – Seminars

Probing life and death decisions with synthetic protein chemistry

22-11-202222-11-2022

With: Prof. Manuel Müller (King’s College London)
Place and room: CH B3 31
Category: Conferences – Seminars

2022 International Symposium on Chemical Biology

08-11-202210-11-2022

With: 15 international leaders in the field of chemical biology
Place and room: Campus Biotech & online
Category: Conferences – Seminars

ChemBio e-seminar by Prof. Ken Yokoyama

25-10-202225-10-2022

With: Prof. Ken Yokoyama Duke University, North Carolina, USA
Online: https://epfl.zoom.us/j/67321697618
Category: Conferences – Seminars

Towards Covalent Inhibitors Addressing Diverse Amino Acids – Unbiased Profiling of the Proteome-Wide Selectivity of Electrophiles

18-10-202218-10-2022

With: Prof. Stephan Hacker (Leiden University)
Place and room: CH G1 495
Category: Conferences – Seminars

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2021

Understanding and predicting cell permeability of compounds in the beyond rule of 5 space

07-12-202107-12-2021

With: Prof. Jan Kihlberg, Uppsala University
Online: https://epfl.zoom.us/j/62430541332
Category: Conferences – Seminars

Translational chemical biology

29-11-202129-11-2021

With: Prof. Gonçalo Bernardes University of Cambridge, UK
Category: Conferences – Seminars

ChemBio Seminar: Natural Product Diversity in Interacting Microbes

16-11-202116-11-2021

With: Prof. Pierre Stallforth, HKI Jena, Germany
Place and room: Online only!!
Online: https://epfl.zoom.us/j/62300612796
Category: Conferences – Seminars

Flycodes: barcoding designer peptides for mass spectrometry enable in vivo antibody screening

02-11-202102-11-2021

With: Prof. Markus Seeger (IMM – Universität Zürich)
Place and room: CH G1 495
Category: Conferences – Seminars

ChemBio e-seminar by Dr. Jordan Meier (NIH National Cancer Institute): New Insights into Acetylation & Oncometabolites from Chemoproteomics

19-10-202119-10-2021

With: https://ccr.cancer.gov/staff-directory/jordan-l-meier#staff-profile-lab-life-tab-9
Online: https://epfl.zoom.us/j/67855065951
Category: Conferences – Seminars

Joint ChemBio & ChemE e-seminar by Prof. Wenjun Zhang (UC Berkeley): Discovery, Biosynthesis and Functional Study of Natural Products

05-10-202105-10-2021

With: https://chemistry.berkeley.edu/faculty/cbe/zhang
Online: https://epfl.zoom.us/j/66146029243
Category: Conferences – Seminars

ChemBio e-seminar by Prof. Sarah Slavoff (Yale University): Dark Matter of the Human Genome

28-09-202128-09-2021

With: https://chem.yale.edu/people/sarah-slavoff
Online: https://epfl.zoom.us/j/63707358272
Category: Conferences – Seminars

Chemical Evolution of Natural Product Structure

21-09-202121-09-2021

With: Prof. Herbert Waldmann, Max Planck Insitute of Molecular Physiology
Online: https://epfl.zoom.us/j/62430541332
Category: Conferences – Seminars

Circluar Chemistry – On the Magic of Molecular Rings

25-05-202125-05-2021

With: Prof. Dr. Felix Hausch, Technical University of Darmstadt
Online: https://epfl.zoom.us/j/82667214199
Category: Conferences – Seminars

Sliding, Pushing, Crashing: the Treacherous Pathways of Chromosome Replication in a Crowded World

11-05-202111-05-2021

With: Karl Duderstadt (MPI Biochemistry, München)
Online: https://epfl.zoom.us/j/88089196947
Category: Conferences – Seminars

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2020

Unravelling the poly(ADP-ribose) code: How the structural diversity of the post-translational modification poly(ADP-ribose) affects biochemical and biological processes

15-12-202015-12-2020

With: Prof. Aswin Mangerich (Universität Konstanz)
Online: https://epfl.zoom.us/j/83488461124
Category: Conferences – Seminars

Controlling Labile Metal Ions in Biological Systems

08-12-202008-12-2020

With: Prof. Justin Wilson, Department of Chemistry and Chemical Biology, Cornell University, USA.
Place and room: Zoom
Online: https://epfl.zoom.us/j/84558660858
Category: Conferences – Seminars

Chemical control of cellular signaling

01-12-202001-12-2020

With: Prof. Christina Woo, Department of Chemistry and Chemical Biology, Harvard University, USA.
Place and room: Zoom
Online: https://epfl.zoom.us/j/87597493164
Category: Conferences – Seminars

Integrative dynamic structural biology of biomolecular assemblies resolved by multi-scale super-resolution FRET spectroscopy and imaging

24-11-202024-11-2020

With: Claus A.M. Seidel (Heinrich Heine University, Germany)
Online: https://epfl.zoom.us/j/81648589177
Category: Conferences – Seminars

Breaking the rules with natural and non-natural cyclic peptides

17-11-202017-11-2020

With: Prof. Scott Lokey, UC Santa Cruz
Place and room: Zoom
Online: https://epfl.zoom.us/j/87665377407
Category: Conferences – Seminars

Automation + Miniaturization = Acceleration

03-11-202003-11-2020

With: Prof. Alexander Dömling, University of Groningen
Place and room: Zoom
Online: https://epfl.zoom.us/j/87346413083
Category: Conferences – Seminars

'Thiol-based Redox Signaling'

13-10-202013-10-2020

With: PD Dr. Tobias P. Dick, German Cancer Research Center (DKFZ), Heidelberg.
Category: Conferences – Seminars

Chemical proteome mining to fight multiresistant bacteria

29-09-202029-09-2020

With: Prof. Dr. Stephan Sieber Professor and Chair of Organic Chemistry II Technical University of Munich
Category: Conferences – Seminars

'Mapping biochemical drivers of phenotypic change'

01-07-202001-07-2020

With: Prof. Daniel F. Jarosz, Associate Professor of Chemical and Systems Biology and of Developmental Biology at Stanford University, USA.
Category: Conferences – Seminars

Harnessing massive peptide libraries to explore the inhibition of epigenetic drug targets

30-06-202030-06-2020

With: Prof. Louise Walport
Category: Conferences – Seminars

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2019

Reprogramming the reactivity of iron in cancer

15-10-201915-10-2019

With: Raphaël Rodriguez
Place and room: BCH 2201
Category: Conferences – Seminars

Redox signaling mechanisms under infection conditions and antibiotics in the major pathogen Staphylococcus aureus

01-10-201901-10-2019

With: Prof. Haike Antelmann
Place and room: BCH 2201
Category: Conferences – Seminars

NMR-based tools for structural biology in gels and cells

20-09-201920-09-2019

With: Prof. Galia Debelouchina, UCSD – University of California San Diego
Place and room: BCH 3303
Category: Conferences – Seminars

A cyclic peptide toolkit to modulate PADI4 activity

03-07-201903-07-2019

With: Dr. Louise Walport
Place and room: BCH 5310
Category: Conferences – Seminars

Protein Epitope Mimetics: from Discovery to the Clinic

02-07-201902-07-2019

With: Dr. Daniel Obrecht, CSO Polyphor
Place and room: CH G1 495
Category: Conferences – Seminars

Roles of ZRANB3 in replication stress response

07-05-201907-05-2019

With: Professor Dragana Ahel (University of Oxford)
Place and room: SV 1717
Category: Conferences – Seminars

Adventures in Targeting Protein Lipdation: Breaking Drug Resistance Using Chemical Biology

09-04-201909-04-2019

With: Prof. Edward Tate (Imperial College London)
Place and room: CH G1 495
Category: Conferences – Seminars

Dynamic chaperone–client-interactions characterized at atomic resolution

09-04-201909-04-2019

With: Prof. Sebastian Hiller (University of Basel)
Place and room: CH G1 495
Category: Conferences – Seminars

dNTPs and maintenance of genome stability

26-02-201926-02-2019

With: Professor Andrei Chabes Dept. of Medical Biochemistry and Biophysics Umeå University SE 901 87 Umeå Sweden Phone: +46 73 620 5446
Place and room: BCH 2218
Category: Conferences – Seminars

Developing small molecule catalysts for chemical protein degradation

19-02-201919-02-2019

With: Prof. Dennis Gillingham
Place and room: BCH 3118
Category: Conferences – Seminars

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2018

Inaugural lecture // Membrane Proteins: from Structure Prediction to Designing Novel Functions

06-12-201806-12-2018

With: Prof. Patrick Barth, Institute of Bioengineering, EPFL
Place and room: SV 1717
Category: Inaugural lectures – Honorary Lecture

Activation of transcription factor Nrf2 as a strategy to restore the cellular redox and protein homeostasis

04-12-201804-12-2018

With: Albena T. Dinkova-Kostova
Place and room: BCH 2201
Category: Conferences – Seminars

The CRL4 ubiquitin ligase: at the intersection of genome stability and drug discover

23-10-201823-10-2018

With: Prof. Nicolas Thomä, FMI Basel, Switzerland
Place and room: BCH 2201
Category: Conferences – Seminars

Ubiquitin E3 ligase activity-based profiling: from Parkin to the impalpable

16-10-201816-10-2018

With: Prof. Satpal Virdee (University of Dundee)
Place and room: BCH 2218
Category: Conferences – Seminars

Peptides and Peptidomimetics for Selective Anion Recognition in Aqueous Solution

02-10-201802-10-2018

With: Prof. Kate Jolliffe, (The University of Sydney, Australia)
Place and room: BCH 3118
Category: Conferences – Seminars

Genetic code expansion for temporal controlled labeling of endogenous expressed proteins

05-09-201805-09-2018

With: Prof. Matthias Meier, Helmholtz Zentrum, Muenchen
Place and room: BCH 4310
Category: Conferences – Seminars

Transcriptional control in time and space

10-07-201810-07-2018

With: Nadine L. Vastenhouw (MPI Molecular Cell Biology and Genetics – Germany)
Place and room: SV 1717
Category: Conferences – Seminars

PROTAC-mediated Protein Degradation: The chemical equivalent of siRNA

21-06-201821-06-2018

With: Prof. Craig Crews, Yale University
Place and room: BCH 2218
Category: Conferences – Seminars

"Protein Self-Assembly by Chemical Design"

20-06-201820-06-2018

With: Akif Tezcan, UCSD
Place and room: BCH 3118
Category: Conferences – Seminars

Expanding the Genetic Code – Chemistry in Living Systems

15-05-201815-05-2018

With: Prof. Kathrin Lang (TU Munich)
Place and room: BCH 2218
Category: Conferences – Seminars

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2017

Decoding chromatin modification states using chemical biology and proteomic approaches

12-12-201712-12-2017

With: Prof. Till Bartke, Institute of Functional Epigenetics Helmholtz Zentrum München
Place and room: BCH 5310
Category: Conferences – Seminars

Selective chemical intervention on protein-protein interactions: from inhibitors to degraders

17-10-201717-10-2017

With: Prof. Alessio Ciulli, University of Dundee
Place and room: BCH 2218
Category: Conferences – Seminars

Peptide‐based probes for lysine deacetylases

20-09-201720-09-2017

With: Prof. Dirk Schwarzer, Universität Tübingen
Place and room: BCH 2218
Category: Conferences – Seminars

Molecular mechanisms of epigenetic regulation

11-09-201711-09-2017

With: Prof. Tatiana Kutateladze Department of Pharmacology University of Colorado School of Medicine, Aurora, Colorado, USA
Place and room: SV1717.A
Category: Conferences – Seminars

X-Ray Crystal Structure of a Chromatosome—the Fundamental Nucleosome-Linker Histone Assembly of Chromatin

22-06-201722-06-2017

With: Prof. Curtis Davey (NTU – Singapore)
Place and room: CH G1 495
Category: Conferences – Seminars

An iron hand over cancer stem cells

27-04-201727-04-2017

With: Prof. Raphael Rodriguez, Institut Curie, Paris
Place and room: BCH 2218
Category: Conferences – Seminars

Probing unfolded and intrinsically disordered proteins with single-molecule spectroscopy

06-04-201706-04-2017

With: Prof. Ben Schuler, University of Zurich
Place and room: BCH 2218
Category: Conferences – Seminars

EPIGENETIC REGULATION OF CHROMATIN DYNAMICS

20-01-201720-01-2017

With: Prof. Michael Poirier, Ohio Stat University
Place and room: CH G1 495
Category: Conferences – Seminars

The power of chemoselectivity: Functional protein-conjugates for proteomic and pharmaceutical research

19-01-201719-01-2017

With: Prof. Christian Hackenberger, Humboldt Universität zu Berlin and Leibniz-Institut für Molekulare Pharmakologie (FMP) – Berlin
Place and room: CH G1 495
Category: Conferences – Seminars

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