Basic and Translational Cancer Research

EPFL research groups

Cathrin Brisken

Breast cancer, mouse genetic, mammary gland development, mouse models, patient derived xenografts, estrogen and progesterone, endocrine disruptors

Michele De Palma

Tumor-associated macrophages, tumor angiogenesis and antiangiogenic therapy Immunotherapy, microRNAs, exosomes and extracellular vesicles, mouse models of cancer, immune cell engineering, lentiviral vector technologies

Douglas Hanahan

Cancer, translational oncology, genetically engineered mouse models of human cancer, tumor microenvironment, angiogenesis, invasion, metastasis, pre-clinical trials

Joerg Huelsken

Tumor heterogeneity and stemness in cancer

Freddy Radtke

Notch, stem and progenitor cells, self-renewing tissues, differentiation, cancer, genetic mouse models

Elisa Oricchio

Cancer genetic, mouse models, therapy, stem cells, lymphoma

Wouter Karthaus

Endocrine cancers, endocrine therapy resistance, stem cell biology, organoid technology

Sebastian Waszak

Computational neuro-oncology, biomedical data science, clinical cancer genomics, diffuse midline glioma, diffuse intrinsic pontine glioma, medulloblastoma, genetic tumour syndromes

Nicolas Thomä – Paternot Chair

Chemical biology, structural Biology, gene expression, oncogenic fusion proteins DNA-bound macromolecular machines, molecular glues, expanding the druggable space in cancer

Sara Gallini

Skin tumor suppression and progression; wound-repair; 2-photon imaging and stem cell biology

Charlotte Bunne

Artificial intelligence, personalized oncology, computer vision, computational biomedicine

Affiliated research groups

Giovanni Ciriello

Cancer genomics & evolution, cell plasticity, chromatin 3D architecture, computational biology

Christoph Merten

Microfluidic technology develpment, single cell analysis, antibody discovery, personalized cancer therapy

Andrea Ablasser

DNA sensing, inflammation, antitumor immunity, cGAS-STING pathway

George Coukos

Tumor immunology, T-cell therapies, cancer vaccines, bioinformatics and engineering, clinical trials

Tatiana Petrova

Transcription, differentiation, cancer stem cells, intestinal and vascular development, lymphedema, cancer

Olivier Michielin

Digital biomarker discovery for precision oncology, digital pathology, radiology, genomics, clinical and molecular data, immuno-oncological treatments